9SR3
Structure of stacked allo-activated CBS conformer by allosteric SAM - by Helical approach
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00901 |
| Number of Residues | 19 |
| Details | CYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KcEffn.AGgSVKdRiSlrM |
| Chain | Residue | Details |
| b | LYS108-MET126 | |
| O | LYS108-MET126 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1392 |
| Details | Domain: {"description":"CBS","evidences":[{"source":"PROSITE-ProRule","id":"PRU00703","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 52 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"11483494","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12173932","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 156 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11483494","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12173932","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 26 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"PubMed","id":"11483494","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12173932","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 26 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 52 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"PubMed","id":"17087506","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA10 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA11 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA12 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA13 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA14 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA15 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA16 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA17 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA18 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA19 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA2 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA20 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA21 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA22 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA23 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA24 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA25 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| Y | LLP119 | covalently attached, electron pair acceptor, electron pair donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay |
| site_id | MCSA26 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| Z | LLP119 | covalently attached, electron pair acceptor, electron pair donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay |
| site_id | MCSA3 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA4 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA5 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA6 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA7 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA8 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
| site_id | MCSA9 |
| Number of Residues | 1 |
| Details | M-CSA 713 |
| Chain | Residue | Details |
