9SMS

BRCA1-A complex: Ubiquitin bound to BRE at the wrist site (focused 3D class)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0006282	biological_process	regulation of DNA repair
A	0006302	biological_process	double-strand break repair
A	0007095	biological_process	mitotic G2 DNA damage checkpoint signaling
A	0008017	molecular_function	microtubule binding
A	0008608	biological_process	attachment of spindle microtubules to kinetochore
A	0010212	biological_process	response to ionizing radiation
A	0016604	cellular_component	nuclear body
A	0031593	molecular_function	polyubiquitin modification-dependent protein binding
A	0044818	biological_process	mitotic G2/M transition checkpoint
A	0045739	biological_process	positive regulation of DNA repair
A	0070531	cellular_component	BRCA1-A complex
A	0090307	biological_process	mitotic spindle assembly
C	0000152	cellular_component	nuclear ubiquitin ligase complex
C	0000268	molecular_function	peroxisome signal sequence receptor activity
C	0005164	molecular_function	tumor necrosis factor receptor binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006282	biological_process	regulation of DNA repair
C	0006302	biological_process	double-strand break repair
C	0006974	biological_process	DNA damage response
C	0007095	biological_process	mitotic G2 DNA damage checkpoint signaling
C	0007165	biological_process	signal transduction
C	0010212	biological_process	response to ionizing radiation
C	0031593	molecular_function	polyubiquitin modification-dependent protein binding
C	0034516	biological_process	response to vitamin B6
C	0043066	biological_process	negative regulation of apoptotic process
C	0044818	biological_process	mitotic G2/M transition checkpoint
C	0045739	biological_process	positive regulation of DNA repair
C	0070531	cellular_component	BRCA1-A complex
C	0070536	biological_process	protein K63-linked deubiquitination
C	0070552	cellular_component	BRISC complex
C	0071479	biological_process	cellular response to ionizing radiation
C	2000001	biological_process	regulation of DNA damage checkpoint
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006282	biological_process	regulation of DNA repair
D	0006302	biological_process	double-strand break repair
D	0007095	biological_process	mitotic G2 DNA damage checkpoint signaling
D	0010212	biological_process	response to ionizing radiation
D	0016604	cellular_component	nuclear body
D	0034516	biological_process	response to vitamin B6
D	0042802	molecular_function	identical protein binding
D	0044818	biological_process	mitotic G2/M transition checkpoint
D	0045739	biological_process	positive regulation of DNA repair
D	0070531	cellular_component	BRCA1-A complex
D	0070552	cellular_component	BRISC complex
D	0140861	biological_process	DNA repair-dependent chromatin remodeling

Functional Information from PROSITE/UniProt

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
S	LYS27-ASP52

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	117
Details	Region: {"description":"UEV-like 1"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	89
Details	Region: {"description":"UEV-like 2"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	203
Details	Region: {"description":"VWFA-like"}

Chain

Residue

Details

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