9SHP
Cryo-EM structure of the endogeneous MIWI in complex with pachytene piRNA at 3.3A
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Region: {"description":"Required for binding 2'-O-methylated 3'-end of piRNAs","evidences":[{"source":"PubMed","id":"21237665","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 136 |
| Details | Region: {"description":"MID region","evidences":[{"source":"PubMed","id":"24757166","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Motif: {"description":"D-box","evidences":[{"source":"PubMed","id":"23328397","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"22121019","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Active site: {"evidences":[{"source":"UniProtKB","id":"A8D8P8","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
