9SCV

Human bisphosphoglycerate mutase (hBPGM) complexed with citrate.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004082	molecular_function	bisphosphoglycerate mutase activity
A	0004619	molecular_function	phosphoglycerate mutase activity
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0006096	biological_process	glycolytic process
A	0007585	biological_process	respiratory gaseous exchange by respiratory system
A	0016868	molecular_function	intramolecular phosphotransferase activity
A	0070062	cellular_component	extracellular exosome
A	1901136	biological_process	carbohydrate derivative catabolic process
B	0003824	molecular_function	catalytic activity
B	0004082	molecular_function	bisphosphoglycerate mutase activity
B	0004619	molecular_function	phosphoglycerate mutase activity
B	0005515	molecular_function	protein binding
B	0005829	cellular_component	cytosol
B	0005975	biological_process	carbohydrate metabolic process
B	0006096	biological_process	glycolytic process
B	0007585	biological_process	respiratory gaseous exchange by respiratory system
B	0016868	molecular_function	intramolecular phosphotransferase activity
B	0070062	cellular_component	extracellular exosome
B	1901136	biological_process	carbohydrate derivative catabolic process
C	0003824	molecular_function	catalytic activity
C	0004082	molecular_function	bisphosphoglycerate mutase activity
C	0004619	molecular_function	phosphoglycerate mutase activity
C	0005515	molecular_function	protein binding
C	0005829	cellular_component	cytosol
C	0005975	biological_process	carbohydrate metabolic process
C	0006096	biological_process	glycolytic process
C	0007585	biological_process	respiratory gaseous exchange by respiratory system
C	0016868	molecular_function	intramolecular phosphotransferase activity
C	0070062	cellular_component	extracellular exosome
C	1901136	biological_process	carbohydrate derivative catabolic process
D	0003824	molecular_function	catalytic activity
D	0004082	molecular_function	bisphosphoglycerate mutase activity
D	0004619	molecular_function	phosphoglycerate mutase activity
D	0005515	molecular_function	protein binding
D	0005829	cellular_component	cytosol
D	0005975	biological_process	carbohydrate metabolic process
D	0006096	biological_process	glycolytic process
D	0007585	biological_process	respiratory gaseous exchange by respiratory system
D	0016868	molecular_function	intramolecular phosphotransferase activity
D	0070062	cellular_component	extracellular exosome
D	1901136	biological_process	carbohydrate derivative catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00175
Number of Residues	10
Details	PG_MUTASE Phosphoglycerate mutase family phosphohistidine signature. MlRHGEgAwN

Chain	Residue	Details
A	MET8-ASN17

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Tele-phosphohistidine intermediate","evidences":[{"source":"PubMed","id":"17052986","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"17052986","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17052986","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	24
Details	Site: {"description":"Not glycated","evidences":[{"source":"PubMed","id":"9832630","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"PubMed","id":"17052986","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	20
Details	Glycosylation: {"description":"N-linked (Glc) (glycation) lysine; in vitro","evidences":[{"source":"PubMed","id":"9832630","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (Glc) (glycation) lysine","evidences":[{"source":"PubMed","id":"9832630","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---