9S8K

Structure of glycogen phosphorylase - tetrameric form - in complex with HPr from Escherichia coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004645	molecular_function	1,4-alpha-oligoglucan phosphorylase activity
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0005980	biological_process	glycogen catabolic process
A	0008184	molecular_function	glycogen phosphorylase activity
A	0018106	biological_process	peptidyl-histidine phosphorylation
A	0030170	molecular_function	pyridoxal phosphate binding
A	0042803	molecular_function	protein homodimerization activity
B	0004645	molecular_function	1,4-alpha-oligoglucan phosphorylase activity
B	0005515	molecular_function	protein binding
B	0005829	cellular_component	cytosol
B	0005980	biological_process	glycogen catabolic process
B	0008184	molecular_function	glycogen phosphorylase activity
B	0018106	biological_process	peptidyl-histidine phosphorylation
B	0030170	molecular_function	pyridoxal phosphate binding
B	0042803	molecular_function	protein homodimerization activity
C	0004645	molecular_function	1,4-alpha-oligoglucan phosphorylase activity
C	0005515	molecular_function	protein binding
C	0005829	cellular_component	cytosol
C	0005980	biological_process	glycogen catabolic process
C	0008184	molecular_function	glycogen phosphorylase activity
C	0018106	biological_process	peptidyl-histidine phosphorylation
C	0030170	molecular_function	pyridoxal phosphate binding
C	0042803	molecular_function	protein homodimerization activity
D	0004645	molecular_function	1,4-alpha-oligoglucan phosphorylase activity
D	0005515	molecular_function	protein binding
D	0005829	cellular_component	cytosol
D	0005980	biological_process	glycogen catabolic process
D	0008184	molecular_function	glycogen phosphorylase activity
D	0018106	biological_process	peptidyl-histidine phosphorylation
D	0030170	molecular_function	pyridoxal phosphate binding
D	0042803	molecular_function	protein homodimerization activity
E	0004857	molecular_function	enzyme inhibitor activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0008047	molecular_function	enzyme activator activity
E	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
E	0016775	molecular_function	phosphotransferase activity, nitrogenous group as acceptor
E	0018106	biological_process	peptidyl-histidine phosphorylation
E	0030234	molecular_function	enzyme regulator activity
E	0043609	biological_process	regulation of carbon utilization
E	0045152	molecular_function	antisigma factor binding
E	0045819	biological_process	positive regulation of glycogen catabolic process
F	0004857	molecular_function	enzyme inhibitor activity
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0008047	molecular_function	enzyme activator activity
F	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
F	0016775	molecular_function	phosphotransferase activity, nitrogenous group as acceptor
F	0018106	biological_process	peptidyl-histidine phosphorylation
F	0030234	molecular_function	enzyme regulator activity
F	0043609	biological_process	regulation of carbon utilization
F	0045152	molecular_function	antisigma factor binding
F	0045819	biological_process	positive regulation of glycogen catabolic process
G	0004857	molecular_function	enzyme inhibitor activity
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0008047	molecular_function	enzyme activator activity
G	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
G	0016775	molecular_function	phosphotransferase activity, nitrogenous group as acceptor
G	0018106	biological_process	peptidyl-histidine phosphorylation
G	0030234	molecular_function	enzyme regulator activity
G	0043609	biological_process	regulation of carbon utilization
G	0045152	molecular_function	antisigma factor binding
G	0045819	biological_process	positive regulation of glycogen catabolic process
H	0004857	molecular_function	enzyme inhibitor activity
H	0005515	molecular_function	protein binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0008047	molecular_function	enzyme activator activity
H	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
H	0016775	molecular_function	phosphotransferase activity, nitrogenous group as acceptor
H	0018106	biological_process	peptidyl-histidine phosphorylation
H	0030234	molecular_function	enzyme regulator activity
H	0043609	biological_process	regulation of carbon utilization
H	0045152	molecular_function	antisigma factor binding
H	0045819	biological_process	positive regulation of glycogen catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00102
Number of Residues	13
Details	PHOSPHORYLASE Phosphorylase pyridoxal-phosphate attachment site. EASGtSnMKfaLN

Chain	Residue	Details
B	GLU654-ASN666
A	GLU654-ASN666

---

site_id	PS00369
Number of Residues	8
Details	PTS_HPR_HIS PTS HPR domain histidine phosphorylation site signature. GLHTRPAA

Chain	Residue	Details
E	GLY13-ALA20

---

site_id	PS00589
Number of Residues	16
Details	PTS_HPR_SER PTS HPR domain serine phosphorylation site signature. GKsASaKSLFKLQtLG

Chain	Residue	Details
E	GLY39-GLY54

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	168
Details	Domain: {"description":"HPr","evidences":[{"source":"PROSITE-ProRule","id":"PRU00681","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Active site: {"description":"Pros-phosphohistidine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00681","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"2261470","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---