9RTP

Crystal structure of NUDT7 in complex with a novel inhibitor

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005777	cellular_component	peroxisome
A	0005782	cellular_component	peroxisomal matrix
A	0005829	cellular_component	cytosol
A	0010945	molecular_function	coenzyme A diphosphatase activity
A	0015938	biological_process	coenzyme A catabolic process
A	0030515	molecular_function	snoRNA binding
A	0036114	biological_process	medium-chain fatty-acyl-CoA catabolic process
A	0044580	biological_process	butyryl-CoA catabolic process
A	0046356	biological_process	acetyl-CoA catabolic process
A	0140933	molecular_function	5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity
A	1901289	biological_process	succinyl-CoA catabolic process
A	1902858	biological_process	propionyl-CoA metabolic process
A	1902859	biological_process	propionyl-CoA catabolic process
A	2001294	biological_process	malonyl-CoA catabolic process

Functional Information from PROSITE/UniProt

site_id	PS01293
Number of Residues	21
Details	NUDIX_COA Nudix CoA signature. LFTvRSeklRrapGevcFPGG

Chain	Residue	Details
A	LEU57-GLY77

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	21
Details	Motif: {"description":"Nudix box"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q99P30","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"Important for coenzyme A binding","evidences":[{"source":"UniProtKB","id":"Q99P30","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q99P30","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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