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9RTN

State 2 MAP 2 SPT6 with SETD2

Functional Information from GO Data
ChainGOidnamespacecontents
G0000428cellular_componentDNA-directed RNA polymerase complex
G0005634cellular_componentnucleus
G0006352biological_processDNA-templated transcription initiation
M0003723molecular_functionRNA binding
M0005515molecular_functionprotein binding
M0005634cellular_componentnucleus
M0005654cellular_componentnucleoplasm
M0006351biological_processDNA-templated transcription
M0006368biological_processtranscription elongation by RNA polymerase II
M0006397biological_processmRNA processing
M0008023cellular_componenttranscription elongation factor complex
M0008380biological_processRNA splicing
M0031491molecular_functionnucleosome binding
M0034728biological_processnucleosome organization
M0042393molecular_functionhistone binding
M0045191biological_processregulation of isotype switching
M0051028biological_processmRNA transport
M0051147biological_processregulation of muscle cell differentiation
M0140673biological_processtranscription elongation-coupled chromatin remodeling
Z0000122biological_processnegative regulation of transcription by RNA polymerase II
Z0003723molecular_functionRNA binding
Z0003729molecular_functionmRNA binding
Z0005515molecular_functionprotein binding
Z0005634cellular_componentnucleus
Z0005654cellular_componentnucleoplasm
Z0006351biological_processDNA-templated transcription
Z0006368biological_processtranscription elongation by RNA polymerase II
Z0016239biological_processpositive regulation of macroautophagy
Z0019899molecular_functionenzyme binding
Z0032044cellular_componentDSIF complex
Z0032785biological_processnegative regulation of DNA-templated transcription, elongation
Z0032786biological_processpositive regulation of DNA-templated transcription, elongation
Z0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
Z0034243biological_processregulation of transcription elongation by RNA polymerase II
Z0045944biological_processpositive regulation of transcription by RNA polymerase II
Z0046982molecular_functionprotein heterodimerization activity
Z0140870molecular_functionRNA polymerase inhibitor activity
Z0160239biological_processtranscription pausing by RNA polymerase II
Functional Information from PROSITE/UniProt
site_idPS01159
Number of Residues26
DetailsWW_DOMAIN_1 WW/rsp5/WWP domain signature. WktardpegkiyYYhvitrq.TQWDPP
ChainResidueDetails
OTRP2395-PRO2420

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI2
Number of Residues31
DetailsDomain: {"description":"KOW 2"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues31
DetailsDomain: {"description":"KOW 3"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues33
DetailsDomain: {"description":"KOW 4"}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues2
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"28892040","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5OIK","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues1
DetailsModified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

246905

PDB entries from 2025-12-31

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