9RRQ
Human TRPC5 in complex with (-) englerin A, partial occupancy (2EA:2LIP stoichiometry) state 1
This is a non-PDB format compatible entry.
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 136 |
| Details | Intramembrane: {"description":"Discontinuously helical; Name=Pre-S1","evidences":[{"source":"PubMed","id":"37137991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X6I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 116 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"37137991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X6I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 80 |
| Details | Transmembrane: {"description":"Helical; Name=S1","evidences":[{"source":"PubMed","id":"37137991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X6I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 56 |
| Details | Transmembrane: {"description":"Helical; Name=S2","evidences":[{"source":"PubMed","id":"37137991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X6I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 80 |
| Details | Transmembrane: {"description":"Helical; Name=S3","evidences":[{"source":"PubMed","id":"37137991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X6I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 352 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"37137991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X6I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 80 |
| Details | Transmembrane: {"description":"Helical; Name=S4","evidences":[{"source":"PubMed","id":"37137991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X6I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 88 |
| Details | Transmembrane: {"description":"Helical; Name=S5","evidences":[{"source":"PubMed","id":"37137991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X6I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 80 |
| Details | Transmembrane: {"description":"Helical; Name=S6","evidences":[{"source":"PubMed","id":"37137991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X6I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 120 |
| Details | Repeat: {"description":"ANK 1","evidences":[{"source":"PubMed","id":"37137991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X6I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 112 |
| Details | Repeat: {"description":"ANK 2","evidences":[{"source":"PubMed","id":"37137991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X6I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 116 |
| Details | Repeat: {"description":"ANK 4","evidences":[{"source":"PubMed","id":"37137991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X6I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37137991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X6I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37137991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X6I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8GVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
