9RM4

Crystal Structure of ZIKV NS2B-NS3 protease in complex with ASAP-0015373

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0003723	molecular_function	RNA binding
AAA	0003724	molecular_function	RNA helicase activity
AAA	0004252	molecular_function	serine-type endopeptidase activity
AAA	0005524	molecular_function	ATP binding
AAA	0044423	cellular_component	virion component
BBB	0003723	molecular_function	RNA binding
BBB	0003724	molecular_function	RNA helicase activity
BBB	0004252	molecular_function	serine-type endopeptidase activity
BBB	0005524	molecular_function	ATP binding
BBB	0044423	cellular_component	virion component

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	Region: {"description":"Disordered","evidences":[{"source":"PubMed","id":"29080786","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Charge relay system; for serine protease NS3 activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00860","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"description":"Charge relay system; for serine protease NS3 activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00860","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"29526431","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---