9RBD
Cryo-EM structure of ANP amyloids from left atrial appendage of atrial fibrillation patient - polymorph A
Functional Information from PROSITE/UniProt
| site_id | PS00263 |
| Number of Residues | 17 |
| Details | NATRIURETIC_PEPTIDE Natriuretic peptides signature. CFGgrmDRIgaqSglGC |
| Chain | Residue | Details |
| J | CYS105-CYS121 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 460 |
| Details | Peptide: {"description":"Atriopeptin-3","featureId":"PRO_0000449732","evidences":[{"source":"UniProtKB","id":"P01161","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 440 |
| Details | Peptide: {"description":"Atriopeptin-2","featureId":"PRO_0000449733","evidences":[{"source":"UniProtKB","id":"P01161","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 400 |
| Details | Peptide: {"description":"Atriopeptin-1","featureId":"PRO_0000449734","evidences":[{"source":"UniProtKB","id":"P01161","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 80 |
| Details | Region: {"description":"Important for degradation of atrial natriuretic peptide by IDE","evidences":[{"source":"PubMed","id":"21098034","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | Site: {"description":"Cleavage; by MME","evidences":[{"source":"PubMed","id":"2972276","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"2528951","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
