9R71

Crystal structure of E. coli Adenylate kinase E114A mutant in complex with inhibitor Ap5a.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0004017	molecular_function	AMP kinase activity
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006172	biological_process	ADP biosynthetic process
A	0009123	biological_process	nucleoside monophosphate metabolic process
A	0009132	biological_process	nucleoside diphosphate metabolic process
A	0009165	biological_process	nucleotide biosynthetic process
A	0015951	biological_process	purine ribonucleotide interconversion
A	0016208	molecular_function	AMP binding
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0044209	biological_process	AMP salvage
A	0046083	biological_process	adenine metabolic process
A	0046940	biological_process	nucleoside monophosphate phosphorylation
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0004017	molecular_function	AMP kinase activity
B	0004550	molecular_function	nucleoside diphosphate kinase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006172	biological_process	ADP biosynthetic process
B	0009123	biological_process	nucleoside monophosphate metabolic process
B	0009132	biological_process	nucleoside diphosphate metabolic process
B	0009165	biological_process	nucleotide biosynthetic process
B	0015951	biological_process	purine ribonucleotide interconversion
B	0016208	molecular_function	AMP binding
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0044209	biological_process	AMP salvage
B	0046083	biological_process	adenine metabolic process
B	0046940	biological_process	nucleoside monophosphate phosphorylation

Functional Information from PROSITE/UniProt

site_id	PS00113
Number of Residues	12
Details	ADENYLATE_KINASE Adenylate kinase signature. FLLDGFPRtipQ

Chain	Residue	Details
A	PHE81-GLN92

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	58
Details	Region: {"description":"NMP","evidences":[{"source":"HAMAP-Rule","id":"MF_00235","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	74
Details	Region: {"description":"LID"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00235","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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