9R2S

Structure of the S.aureus ClpP degradation chamber in the context of the MecA/ClpC/CLpC complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
Pa	0004176	molecular_function	ATP-dependent peptidase activity
Pa	0004252	molecular_function	serine-type endopeptidase activity
Pa	0005737	cellular_component	cytoplasm
Pa	0006508	biological_process	proteolysis
Pa	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pa	0008233	molecular_function	peptidase activity
Pa	0008236	molecular_function	serine-type peptidase activity
Pa	0009368	cellular_component	endopeptidase Clp complex
Pa	0016787	molecular_function	hydrolase activity
Pa	0042802	molecular_function	identical protein binding
Pa	0051117	molecular_function	ATPase binding
Pb	0004176	molecular_function	ATP-dependent peptidase activity
Pb	0004252	molecular_function	serine-type endopeptidase activity
Pb	0005737	cellular_component	cytoplasm
Pb	0006508	biological_process	proteolysis
Pb	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pb	0008233	molecular_function	peptidase activity
Pb	0008236	molecular_function	serine-type peptidase activity
Pb	0009368	cellular_component	endopeptidase Clp complex
Pb	0016787	molecular_function	hydrolase activity
Pb	0042802	molecular_function	identical protein binding
Pb	0051117	molecular_function	ATPase binding
Pc	0004176	molecular_function	ATP-dependent peptidase activity
Pc	0004252	molecular_function	serine-type endopeptidase activity
Pc	0005737	cellular_component	cytoplasm
Pc	0006508	biological_process	proteolysis
Pc	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pc	0008233	molecular_function	peptidase activity
Pc	0008236	molecular_function	serine-type peptidase activity
Pc	0009368	cellular_component	endopeptidase Clp complex
Pc	0016787	molecular_function	hydrolase activity
Pc	0042802	molecular_function	identical protein binding
Pc	0051117	molecular_function	ATPase binding
Pd	0004176	molecular_function	ATP-dependent peptidase activity
Pd	0004252	molecular_function	serine-type endopeptidase activity
Pd	0005737	cellular_component	cytoplasm
Pd	0006508	biological_process	proteolysis
Pd	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pd	0008233	molecular_function	peptidase activity
Pd	0008236	molecular_function	serine-type peptidase activity
Pd	0009368	cellular_component	endopeptidase Clp complex
Pd	0016787	molecular_function	hydrolase activity
Pd	0042802	molecular_function	identical protein binding
Pd	0051117	molecular_function	ATPase binding
Pe	0004176	molecular_function	ATP-dependent peptidase activity
Pe	0004252	molecular_function	serine-type endopeptidase activity
Pe	0005737	cellular_component	cytoplasm
Pe	0006508	biological_process	proteolysis
Pe	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pe	0008233	molecular_function	peptidase activity
Pe	0008236	molecular_function	serine-type peptidase activity
Pe	0009368	cellular_component	endopeptidase Clp complex
Pe	0016787	molecular_function	hydrolase activity
Pe	0042802	molecular_function	identical protein binding
Pe	0051117	molecular_function	ATPase binding
Pf	0004176	molecular_function	ATP-dependent peptidase activity
Pf	0004252	molecular_function	serine-type endopeptidase activity
Pf	0005737	cellular_component	cytoplasm
Pf	0006508	biological_process	proteolysis
Pf	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pf	0008233	molecular_function	peptidase activity
Pf	0008236	molecular_function	serine-type peptidase activity
Pf	0009368	cellular_component	endopeptidase Clp complex
Pf	0016787	molecular_function	hydrolase activity
Pf	0042802	molecular_function	identical protein binding
Pf	0051117	molecular_function	ATPase binding
Pg	0004176	molecular_function	ATP-dependent peptidase activity
Pg	0004252	molecular_function	serine-type endopeptidase activity
Pg	0005737	cellular_component	cytoplasm
Pg	0006508	biological_process	proteolysis
Pg	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pg	0008233	molecular_function	peptidase activity
Pg	0008236	molecular_function	serine-type peptidase activity
Pg	0009368	cellular_component	endopeptidase Clp complex
Pg	0016787	molecular_function	hydrolase activity
Pg	0042802	molecular_function	identical protein binding
Pg	0051117	molecular_function	ATPase binding
Ph	0004176	molecular_function	ATP-dependent peptidase activity
Ph	0004252	molecular_function	serine-type endopeptidase activity
Ph	0005737	cellular_component	cytoplasm
Ph	0006508	biological_process	proteolysis
Ph	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Ph	0008233	molecular_function	peptidase activity
Ph	0008236	molecular_function	serine-type peptidase activity
Ph	0009368	cellular_component	endopeptidase Clp complex
Ph	0016787	molecular_function	hydrolase activity
Ph	0042802	molecular_function	identical protein binding
Ph	0051117	molecular_function	ATPase binding
Pi	0004176	molecular_function	ATP-dependent peptidase activity
Pi	0004252	molecular_function	serine-type endopeptidase activity
Pi	0005737	cellular_component	cytoplasm
Pi	0006508	biological_process	proteolysis
Pi	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pi	0008233	molecular_function	peptidase activity
Pi	0008236	molecular_function	serine-type peptidase activity
Pi	0009368	cellular_component	endopeptidase Clp complex
Pi	0016787	molecular_function	hydrolase activity
Pi	0042802	molecular_function	identical protein binding
Pi	0051117	molecular_function	ATPase binding
Pl	0004176	molecular_function	ATP-dependent peptidase activity
Pl	0004252	molecular_function	serine-type endopeptidase activity
Pl	0005737	cellular_component	cytoplasm
Pl	0006508	biological_process	proteolysis
Pl	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pl	0008233	molecular_function	peptidase activity
Pl	0008236	molecular_function	serine-type peptidase activity
Pl	0009368	cellular_component	endopeptidase Clp complex
Pl	0016787	molecular_function	hydrolase activity
Pl	0042802	molecular_function	identical protein binding
Pl	0051117	molecular_function	ATPase binding
Pm	0004176	molecular_function	ATP-dependent peptidase activity
Pm	0004252	molecular_function	serine-type endopeptidase activity
Pm	0005737	cellular_component	cytoplasm
Pm	0006508	biological_process	proteolysis
Pm	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pm	0008233	molecular_function	peptidase activity
Pm	0008236	molecular_function	serine-type peptidase activity
Pm	0009368	cellular_component	endopeptidase Clp complex
Pm	0016787	molecular_function	hydrolase activity
Pm	0042802	molecular_function	identical protein binding
Pm	0051117	molecular_function	ATPase binding
Pn	0004176	molecular_function	ATP-dependent peptidase activity
Pn	0004252	molecular_function	serine-type endopeptidase activity
Pn	0005737	cellular_component	cytoplasm
Pn	0006508	biological_process	proteolysis
Pn	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pn	0008233	molecular_function	peptidase activity
Pn	0008236	molecular_function	serine-type peptidase activity
Pn	0009368	cellular_component	endopeptidase Clp complex
Pn	0016787	molecular_function	hydrolase activity
Pn	0042802	molecular_function	identical protein binding
Pn	0051117	molecular_function	ATPase binding
Po	0004176	molecular_function	ATP-dependent peptidase activity
Po	0004252	molecular_function	serine-type endopeptidase activity
Po	0005737	cellular_component	cytoplasm
Po	0006508	biological_process	proteolysis
Po	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Po	0008233	molecular_function	peptidase activity
Po	0008236	molecular_function	serine-type peptidase activity
Po	0009368	cellular_component	endopeptidase Clp complex
Po	0016787	molecular_function	hydrolase activity
Po	0042802	molecular_function	identical protein binding
Po	0051117	molecular_function	ATPase binding
Pq	0004176	molecular_function	ATP-dependent peptidase activity
Pq	0004252	molecular_function	serine-type endopeptidase activity
Pq	0005737	cellular_component	cytoplasm
Pq	0006508	biological_process	proteolysis
Pq	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
Pq	0008233	molecular_function	peptidase activity
Pq	0008236	molecular_function	serine-type peptidase activity
Pq	0009368	cellular_component	endopeptidase Clp complex
Pq	0016787	molecular_function	hydrolase activity
Pq	0042802	molecular_function	identical protein binding
Pq	0051117	molecular_function	ATPase binding

Functional Information from PROSITE/UniProt

site_id	PS00381
Number of Residues	12
Details	CLP_PROTEASE_SER Endopeptidase Clp serine active site. TicIGmAASMGS

Chain	Residue	Details
Pb	THR90-SER101

---

site_id	PS00382
Number of Residues	14
Details	CLP_PROTEASE_HIS Endopeptidase Clp histidine active site. RfalPnaeVMIHQP

Chain	Residue	Details
Pb	ARG112-PRO125

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_00444","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00444","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---