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9QYN

Alpha-synuclein K21A fibril type 1A polymorph in the presence of ATP

Functional Information from GO Data
ChainGOidnamespacecontents
G0000122biological_processnegative regulation of transcription by RNA polymerase II
G0000149molecular_functionSNARE binding
G0000287molecular_functionmagnesium ion binding
G0000976molecular_functiontranscription cis-regulatory region binding
G0001774biological_processmicroglial cell activation
G0001921biological_processpositive regulation of receptor recycling
G0001963biological_processsynaptic transmission, dopaminergic
G0003779molecular_functionactin binding
G0004857molecular_functionenzyme inhibitor activity
G0004860molecular_functionprotein kinase inhibitor activity
G0004869molecular_functioncysteine-type endopeptidase inhibitor activity
G0005504molecular_functionfatty acid binding
G0005507molecular_functioncopper ion binding
G0005509molecular_functioncalcium ion binding
G0005515molecular_functionprotein binding
G0005543molecular_functionphospholipid binding
G0005576cellular_componentextracellular region
G0005615cellular_componentextracellular space
G0005634cellular_componentnucleus
G0005640cellular_componentnuclear outer membrane
G0005737cellular_componentcytoplasm
G0005739cellular_componentmitochondrion
G0005741cellular_componentmitochondrial outer membrane
G0005743cellular_componentmitochondrial inner membrane
G0005759cellular_componentmitochondrial matrix
G0005764cellular_componentlysosome
G0005829cellular_componentcytosol
G0005840cellular_componentribosome
G0005856cellular_componentcytoskeleton
G0005886cellular_componentplasma membrane
G0005938cellular_componentcell cortex
G0006749biological_processglutathione metabolic process
G0008017molecular_functionmicrotubule binding
G0008021cellular_componentsynaptic vesicle
G0008047molecular_functionenzyme activator activity
G0008198molecular_functionferrous iron binding
G0008270molecular_functionzinc ion binding
G0008289molecular_functionlipid binding
G0010040biological_processresponse to iron(II) ion
G0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
G0014059biological_processregulation of dopamine secretion
G0015629cellular_componentactin cytoskeleton
G0015631molecular_functiontubulin binding
G0016020cellular_componentmembrane
G0016079biological_processsynaptic vesicle exocytosis
G0016082biological_processsynaptic vesicle priming
G0016234cellular_componentinclusion body
G0016491molecular_functionoxidoreductase activity
G0019894molecular_functionkinesin binding
G0019899molecular_functionenzyme binding
G0019904molecular_functionprotein domain specific binding
G0030424cellular_componentaxon
G0030426cellular_componentgrowth cone
G0030544molecular_functionHsp70 protein binding
G0030659cellular_componentcytoplasmic vesicle membrane
G0030672cellular_componentsynaptic vesicle membrane
G0031092cellular_componentplatelet alpha granule membrane
G0031115biological_processnegative regulation of microtubule polymerization
G0031623biological_processreceptor internalization
G0031648biological_processprotein destabilization
G0032026biological_processresponse to magnesium ion
G0032496biological_processresponse to lipopolysaccharide
G0032991cellular_componentprotein-containing complex
G0034341biological_processresponse to type II interferon
G0034599biological_processcellular response to oxidative stress
G0035493biological_processSNARE complex assembly
G0035543biological_processpositive regulation of SNARE complex assembly
G0042220biological_processresponse to cocaine
G0042393molecular_functionhistone binding
G0042416biological_processdopamine biosynthetic process
G0042802molecular_functionidentical protein binding
G0043014molecular_functionalpha-tubulin binding
G0043025cellular_componentneuronal cell body
G0043065biological_processpositive regulation of apoptotic process
G0043066biological_processnegative regulation of apoptotic process
G0043195cellular_componentterminal bouton
G0043274molecular_functionphospholipase binding
G0043524biological_processnegative regulation of neuron apoptotic process
G0043679cellular_componentaxon terminus
G0044344biological_processcellular response to fibroblast growth factor stimulus
G0045202cellular_componentsynapse
G0045807biological_processpositive regulation of endocytosis
G0045920biological_processnegative regulation of exocytosis
G0045921biological_processpositive regulation of exocytosis
G0045963biological_processnegative regulation of dopamine metabolic process
G0046872molecular_functionmetal ion binding
G0048148biological_processbehavioral response to cocaine
G0048156molecular_functiontau protein binding
G0048471cellular_componentperinuclear region of cytoplasm
G0048487molecular_functionbeta-tubulin binding
G0048488biological_processsynaptic vesicle endocytosis
G0048489biological_processsynaptic vesicle transport
G0050729biological_processpositive regulation of inflammatory response
G0050808biological_processsynapse organization
G0051219molecular_functionphosphoprotein binding
G0051259biological_processprotein complex oligomerization
G0051262biological_processprotein tetramerization
G0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
G0051583biological_processdopamine uptake involved in synaptic transmission
G0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
G0051612biological_processnegative regulation of serotonin uptake
G0051621biological_processregulation of norepinephrine uptake
G0051622biological_processnegative regulation of norepinephrine uptake
G0055074biological_processcalcium ion homeostasis
G0060732biological_processpositive regulation of inositol phosphate biosynthetic process
G0060961molecular_functionphospholipase D inhibitor activity
G0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
G0070507biological_processregulation of microtubule cytoskeleton organization
G0070555biological_processresponse to interleukin-1
G0070840molecular_functiondynein complex binding
G0071280biological_processcellular response to copper ion
G0071872biological_processcellular response to epinephrine stimulus
G0097413cellular_componentLewy body
G0097435biological_processsupramolecular fiber organization
G0098793cellular_componentpresynapse
G0099512cellular_componentsupramolecular fiber
G0140311molecular_functionprotein sequestering activity
G0141108molecular_functiontransporter regulator activity
G1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
G1903136molecular_functioncuprous ion binding
G1903285biological_processpositive regulation of hydrogen peroxide catabolic process
G1903421biological_processregulation of synaptic vesicle recycling
G1903426biological_processregulation of reactive oxygen species biosynthetic process
G1904307biological_processresponse to desipramine
G1904377biological_processpositive regulation of protein localization to cell periphery
G1904715biological_processnegative regulation of chaperone-mediated autophagy
G1905606biological_processregulation of presynapse assembly
G1990000biological_processamyloid fibril formation
G2000377biological_processregulation of reactive oxygen species metabolic process
H0000122biological_processnegative regulation of transcription by RNA polymerase II
H0000149molecular_functionSNARE binding
H0000287molecular_functionmagnesium ion binding
H0000976molecular_functiontranscription cis-regulatory region binding
H0001774biological_processmicroglial cell activation
H0001921biological_processpositive regulation of receptor recycling
H0001963biological_processsynaptic transmission, dopaminergic
H0003779molecular_functionactin binding
H0004857molecular_functionenzyme inhibitor activity
H0004860molecular_functionprotein kinase inhibitor activity
H0004869molecular_functioncysteine-type endopeptidase inhibitor activity
H0005504molecular_functionfatty acid binding
H0005507molecular_functioncopper ion binding
H0005509molecular_functioncalcium ion binding
H0005515molecular_functionprotein binding
H0005543molecular_functionphospholipid binding
H0005576cellular_componentextracellular region
H0005615cellular_componentextracellular space
H0005634cellular_componentnucleus
H0005640cellular_componentnuclear outer membrane
H0005737cellular_componentcytoplasm
H0005739cellular_componentmitochondrion
H0005741cellular_componentmitochondrial outer membrane
H0005743cellular_componentmitochondrial inner membrane
H0005759cellular_componentmitochondrial matrix
H0005764cellular_componentlysosome
H0005829cellular_componentcytosol
H0005840cellular_componentribosome
H0005856cellular_componentcytoskeleton
H0005886cellular_componentplasma membrane
H0005938cellular_componentcell cortex
H0006749biological_processglutathione metabolic process
H0008017molecular_functionmicrotubule binding
H0008021cellular_componentsynaptic vesicle
H0008047molecular_functionenzyme activator activity
H0008198molecular_functionferrous iron binding
H0008270molecular_functionzinc ion binding
H0008289molecular_functionlipid binding
H0010040biological_processresponse to iron(II) ion
H0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
H0014059biological_processregulation of dopamine secretion
H0015629cellular_componentactin cytoskeleton
H0015631molecular_functiontubulin binding
H0016020cellular_componentmembrane
H0016079biological_processsynaptic vesicle exocytosis
H0016082biological_processsynaptic vesicle priming
H0016234cellular_componentinclusion body
H0016491molecular_functionoxidoreductase activity
H0019894molecular_functionkinesin binding
H0019899molecular_functionenzyme binding
H0019904molecular_functionprotein domain specific binding
H0030424cellular_componentaxon
H0030426cellular_componentgrowth cone
H0030544molecular_functionHsp70 protein binding
H0030659cellular_componentcytoplasmic vesicle membrane
H0030672cellular_componentsynaptic vesicle membrane
H0031092cellular_componentplatelet alpha granule membrane
H0031115biological_processnegative regulation of microtubule polymerization
H0031623biological_processreceptor internalization
H0031648biological_processprotein destabilization
H0032026biological_processresponse to magnesium ion
H0032496biological_processresponse to lipopolysaccharide
H0032991cellular_componentprotein-containing complex
H0034341biological_processresponse to type II interferon
H0034599biological_processcellular response to oxidative stress
H0035493biological_processSNARE complex assembly
H0035543biological_processpositive regulation of SNARE complex assembly
H0042220biological_processresponse to cocaine
H0042393molecular_functionhistone binding
H0042416biological_processdopamine biosynthetic process
H0042802molecular_functionidentical protein binding
H0043014molecular_functionalpha-tubulin binding
H0043025cellular_componentneuronal cell body
H0043065biological_processpositive regulation of apoptotic process
H0043066biological_processnegative regulation of apoptotic process
H0043195cellular_componentterminal bouton
H0043274molecular_functionphospholipase binding
H0043524biological_processnegative regulation of neuron apoptotic process
H0043679cellular_componentaxon terminus
H0044344biological_processcellular response to fibroblast growth factor stimulus
H0045202cellular_componentsynapse
H0045807biological_processpositive regulation of endocytosis
H0045920biological_processnegative regulation of exocytosis
H0045921biological_processpositive regulation of exocytosis
H0045963biological_processnegative regulation of dopamine metabolic process
H0046872molecular_functionmetal ion binding
H0048148biological_processbehavioral response to cocaine
H0048156molecular_functiontau protein binding
H0048471cellular_componentperinuclear region of cytoplasm
H0048487molecular_functionbeta-tubulin binding
H0048488biological_processsynaptic vesicle endocytosis
H0048489biological_processsynaptic vesicle transport
H0050729biological_processpositive regulation of inflammatory response
H0050808biological_processsynapse organization
H0051219molecular_functionphosphoprotein binding
H0051259biological_processprotein complex oligomerization
H0051262biological_processprotein tetramerization
H0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
H0051583biological_processdopamine uptake involved in synaptic transmission
H0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
H0051612biological_processnegative regulation of serotonin uptake
H0051621biological_processregulation of norepinephrine uptake
H0051622biological_processnegative regulation of norepinephrine uptake
H0055074biological_processcalcium ion homeostasis
H0060732biological_processpositive regulation of inositol phosphate biosynthetic process
H0060961molecular_functionphospholipase D inhibitor activity
H0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
H0070507biological_processregulation of microtubule cytoskeleton organization
H0070555biological_processresponse to interleukin-1
H0070840molecular_functiondynein complex binding
H0071280biological_processcellular response to copper ion
H0071872biological_processcellular response to epinephrine stimulus
H0097413cellular_componentLewy body
H0097435biological_processsupramolecular fiber organization
H0098793cellular_componentpresynapse
H0099512cellular_componentsupramolecular fiber
H0140311molecular_functionprotein sequestering activity
H0141108molecular_functiontransporter regulator activity
H1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
H1903136molecular_functioncuprous ion binding
H1903285biological_processpositive regulation of hydrogen peroxide catabolic process
H1903421biological_processregulation of synaptic vesicle recycling
H1903426biological_processregulation of reactive oxygen species biosynthetic process
H1904307biological_processresponse to desipramine
H1904377biological_processpositive regulation of protein localization to cell periphery
H1904715biological_processnegative regulation of chaperone-mediated autophagy
H1905606biological_processregulation of presynapse assembly
H1990000biological_processamyloid fibril formation
H2000377biological_processregulation of reactive oxygen species metabolic process
I0000122biological_processnegative regulation of transcription by RNA polymerase II
I0000149molecular_functionSNARE binding
I0000287molecular_functionmagnesium ion binding
I0000976molecular_functiontranscription cis-regulatory region binding
I0001774biological_processmicroglial cell activation
I0001921biological_processpositive regulation of receptor recycling
I0001963biological_processsynaptic transmission, dopaminergic
I0003779molecular_functionactin binding
I0004857molecular_functionenzyme inhibitor activity
I0004860molecular_functionprotein kinase inhibitor activity
I0004869molecular_functioncysteine-type endopeptidase inhibitor activity
I0005504molecular_functionfatty acid binding
I0005507molecular_functioncopper ion binding
I0005509molecular_functioncalcium ion binding
I0005515molecular_functionprotein binding
I0005543molecular_functionphospholipid binding
I0005576cellular_componentextracellular region
I0005615cellular_componentextracellular space
I0005634cellular_componentnucleus
I0005640cellular_componentnuclear outer membrane
I0005737cellular_componentcytoplasm
I0005739cellular_componentmitochondrion
I0005741cellular_componentmitochondrial outer membrane
I0005743cellular_componentmitochondrial inner membrane
I0005759cellular_componentmitochondrial matrix
I0005764cellular_componentlysosome
I0005829cellular_componentcytosol
I0005840cellular_componentribosome
I0005856cellular_componentcytoskeleton
I0005886cellular_componentplasma membrane
I0005938cellular_componentcell cortex
I0006749biological_processglutathione metabolic process
I0008017molecular_functionmicrotubule binding
I0008021cellular_componentsynaptic vesicle
I0008047molecular_functionenzyme activator activity
I0008198molecular_functionferrous iron binding
I0008270molecular_functionzinc ion binding
I0008289molecular_functionlipid binding
I0010040biological_processresponse to iron(II) ion
I0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
I0014059biological_processregulation of dopamine secretion
I0015629cellular_componentactin cytoskeleton
I0015631molecular_functiontubulin binding
I0016020cellular_componentmembrane
I0016079biological_processsynaptic vesicle exocytosis
I0016082biological_processsynaptic vesicle priming
I0016234cellular_componentinclusion body
I0016491molecular_functionoxidoreductase activity
I0019894molecular_functionkinesin binding
I0019899molecular_functionenzyme binding
I0019904molecular_functionprotein domain specific binding
I0030424cellular_componentaxon
I0030426cellular_componentgrowth cone
I0030544molecular_functionHsp70 protein binding
I0030659cellular_componentcytoplasmic vesicle membrane
I0030672cellular_componentsynaptic vesicle membrane
I0031092cellular_componentplatelet alpha granule membrane
I0031115biological_processnegative regulation of microtubule polymerization
I0031623biological_processreceptor internalization
I0031648biological_processprotein destabilization
I0032026biological_processresponse to magnesium ion
I0032496biological_processresponse to lipopolysaccharide
I0032991cellular_componentprotein-containing complex
I0034341biological_processresponse to type II interferon
I0034599biological_processcellular response to oxidative stress
I0035493biological_processSNARE complex assembly
I0035543biological_processpositive regulation of SNARE complex assembly
I0042220biological_processresponse to cocaine
I0042393molecular_functionhistone binding
I0042416biological_processdopamine biosynthetic process
I0042802molecular_functionidentical protein binding
I0043014molecular_functionalpha-tubulin binding
I0043025cellular_componentneuronal cell body
I0043065biological_processpositive regulation of apoptotic process
I0043066biological_processnegative regulation of apoptotic process
I0043195cellular_componentterminal bouton
I0043274molecular_functionphospholipase binding
I0043524biological_processnegative regulation of neuron apoptotic process
I0043679cellular_componentaxon terminus
I0044344biological_processcellular response to fibroblast growth factor stimulus
I0045202cellular_componentsynapse
I0045807biological_processpositive regulation of endocytosis
I0045920biological_processnegative regulation of exocytosis
I0045921biological_processpositive regulation of exocytosis
I0045963biological_processnegative regulation of dopamine metabolic process
I0046872molecular_functionmetal ion binding
I0048148biological_processbehavioral response to cocaine
I0048156molecular_functiontau protein binding
I0048471cellular_componentperinuclear region of cytoplasm
I0048487molecular_functionbeta-tubulin binding
I0048488biological_processsynaptic vesicle endocytosis
I0048489biological_processsynaptic vesicle transport
I0050729biological_processpositive regulation of inflammatory response
I0050808biological_processsynapse organization
I0051219molecular_functionphosphoprotein binding
I0051259biological_processprotein complex oligomerization
I0051262biological_processprotein tetramerization
I0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
I0051583biological_processdopamine uptake involved in synaptic transmission
I0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
I0051612biological_processnegative regulation of serotonin uptake
I0051621biological_processregulation of norepinephrine uptake
I0051622biological_processnegative regulation of norepinephrine uptake
I0055074biological_processcalcium ion homeostasis
I0060732biological_processpositive regulation of inositol phosphate biosynthetic process
I0060961molecular_functionphospholipase D inhibitor activity
I0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
I0070507biological_processregulation of microtubule cytoskeleton organization
I0070555biological_processresponse to interleukin-1
I0070840molecular_functiondynein complex binding
I0071280biological_processcellular response to copper ion
I0071872biological_processcellular response to epinephrine stimulus
I0097413cellular_componentLewy body
I0097435biological_processsupramolecular fiber organization
I0098793cellular_componentpresynapse
I0099512cellular_componentsupramolecular fiber
I0140311molecular_functionprotein sequestering activity
I0141108molecular_functiontransporter regulator activity
I1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
I1903136molecular_functioncuprous ion binding
I1903285biological_processpositive regulation of hydrogen peroxide catabolic process
I1903421biological_processregulation of synaptic vesicle recycling
I1903426biological_processregulation of reactive oxygen species biosynthetic process
I1904307biological_processresponse to desipramine
I1904377biological_processpositive regulation of protein localization to cell periphery
I1904715biological_processnegative regulation of chaperone-mediated autophagy
I1905606biological_processregulation of presynapse assembly
I1990000biological_processamyloid fibril formation
I2000377biological_processregulation of reactive oxygen species metabolic process
J0000122biological_processnegative regulation of transcription by RNA polymerase II
J0000149molecular_functionSNARE binding
J0000287molecular_functionmagnesium ion binding
J0000976molecular_functiontranscription cis-regulatory region binding
J0001774biological_processmicroglial cell activation
J0001921biological_processpositive regulation of receptor recycling
J0001963biological_processsynaptic transmission, dopaminergic
J0003779molecular_functionactin binding
J0004857molecular_functionenzyme inhibitor activity
J0004860molecular_functionprotein kinase inhibitor activity
J0004869molecular_functioncysteine-type endopeptidase inhibitor activity
J0005504molecular_functionfatty acid binding
J0005507molecular_functioncopper ion binding
J0005509molecular_functioncalcium ion binding
J0005515molecular_functionprotein binding
J0005543molecular_functionphospholipid binding
J0005576cellular_componentextracellular region
J0005615cellular_componentextracellular space
J0005634cellular_componentnucleus
J0005640cellular_componentnuclear outer membrane
J0005737cellular_componentcytoplasm
J0005739cellular_componentmitochondrion
J0005741cellular_componentmitochondrial outer membrane
J0005743cellular_componentmitochondrial inner membrane
J0005759cellular_componentmitochondrial matrix
J0005764cellular_componentlysosome
J0005829cellular_componentcytosol
J0005840cellular_componentribosome
J0005856cellular_componentcytoskeleton
J0005886cellular_componentplasma membrane
J0005938cellular_componentcell cortex
J0006749biological_processglutathione metabolic process
J0008017molecular_functionmicrotubule binding
J0008021cellular_componentsynaptic vesicle
J0008047molecular_functionenzyme activator activity
J0008198molecular_functionferrous iron binding
J0008270molecular_functionzinc ion binding
J0008289molecular_functionlipid binding
J0010040biological_processresponse to iron(II) ion
J0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
J0014059biological_processregulation of dopamine secretion
J0015629cellular_componentactin cytoskeleton
J0015631molecular_functiontubulin binding
J0016020cellular_componentmembrane
J0016079biological_processsynaptic vesicle exocytosis
J0016082biological_processsynaptic vesicle priming
J0016234cellular_componentinclusion body
J0016491molecular_functionoxidoreductase activity
J0019894molecular_functionkinesin binding
J0019899molecular_functionenzyme binding
J0019904molecular_functionprotein domain specific binding
J0030424cellular_componentaxon
J0030426cellular_componentgrowth cone
J0030544molecular_functionHsp70 protein binding
J0030659cellular_componentcytoplasmic vesicle membrane
J0030672cellular_componentsynaptic vesicle membrane
J0031092cellular_componentplatelet alpha granule membrane
J0031115biological_processnegative regulation of microtubule polymerization
J0031623biological_processreceptor internalization
J0031648biological_processprotein destabilization
J0032026biological_processresponse to magnesium ion
J0032496biological_processresponse to lipopolysaccharide
J0032991cellular_componentprotein-containing complex
J0034341biological_processresponse to type II interferon
J0034599biological_processcellular response to oxidative stress
J0035493biological_processSNARE complex assembly
J0035543biological_processpositive regulation of SNARE complex assembly
J0042220biological_processresponse to cocaine
J0042393molecular_functionhistone binding
J0042416biological_processdopamine biosynthetic process
J0042802molecular_functionidentical protein binding
J0043014molecular_functionalpha-tubulin binding
J0043025cellular_componentneuronal cell body
J0043065biological_processpositive regulation of apoptotic process
J0043066biological_processnegative regulation of apoptotic process
J0043195cellular_componentterminal bouton
J0043274molecular_functionphospholipase binding
J0043524biological_processnegative regulation of neuron apoptotic process
J0043679cellular_componentaxon terminus
J0044344biological_processcellular response to fibroblast growth factor stimulus
J0045202cellular_componentsynapse
J0045807biological_processpositive regulation of endocytosis
J0045920biological_processnegative regulation of exocytosis
J0045921biological_processpositive regulation of exocytosis
J0045963biological_processnegative regulation of dopamine metabolic process
J0046872molecular_functionmetal ion binding
J0048148biological_processbehavioral response to cocaine
J0048156molecular_functiontau protein binding
J0048471cellular_componentperinuclear region of cytoplasm
J0048487molecular_functionbeta-tubulin binding
J0048488biological_processsynaptic vesicle endocytosis
J0048489biological_processsynaptic vesicle transport
J0050729biological_processpositive regulation of inflammatory response
J0050808biological_processsynapse organization
J0051219molecular_functionphosphoprotein binding
J0051259biological_processprotein complex oligomerization
J0051262biological_processprotein tetramerization
J0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
J0051583biological_processdopamine uptake involved in synaptic transmission
J0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
J0051612biological_processnegative regulation of serotonin uptake
J0051621biological_processregulation of norepinephrine uptake
J0051622biological_processnegative regulation of norepinephrine uptake
J0055074biological_processcalcium ion homeostasis
J0060732biological_processpositive regulation of inositol phosphate biosynthetic process
J0060961molecular_functionphospholipase D inhibitor activity
J0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
J0070507biological_processregulation of microtubule cytoskeleton organization
J0070555biological_processresponse to interleukin-1
J0070840molecular_functiondynein complex binding
J0071280biological_processcellular response to copper ion
J0071872biological_processcellular response to epinephrine stimulus
J0097413cellular_componentLewy body
J0097435biological_processsupramolecular fiber organization
J0098793cellular_componentpresynapse
J0099512cellular_componentsupramolecular fiber
J0140311molecular_functionprotein sequestering activity
J0141108molecular_functiontransporter regulator activity
J1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
J1903136molecular_functioncuprous ion binding
J1903285biological_processpositive regulation of hydrogen peroxide catabolic process
J1903421biological_processregulation of synaptic vesicle recycling
J1903426biological_processregulation of reactive oxygen species biosynthetic process
J1904307biological_processresponse to desipramine
J1904377biological_processpositive regulation of protein localization to cell periphery
J1904715biological_processnegative regulation of chaperone-mediated autophagy
J1905606biological_processregulation of presynapse assembly
J1990000biological_processamyloid fibril formation
J2000377biological_processregulation of reactive oxygen species metabolic process
K0000122biological_processnegative regulation of transcription by RNA polymerase II
K0000149molecular_functionSNARE binding
K0000287molecular_functionmagnesium ion binding
K0000976molecular_functiontranscription cis-regulatory region binding
K0001774biological_processmicroglial cell activation
K0001921biological_processpositive regulation of receptor recycling
K0001963biological_processsynaptic transmission, dopaminergic
K0003779molecular_functionactin binding
K0004857molecular_functionenzyme inhibitor activity
K0004860molecular_functionprotein kinase inhibitor activity
K0004869molecular_functioncysteine-type endopeptidase inhibitor activity
K0005504molecular_functionfatty acid binding
K0005507molecular_functioncopper ion binding
K0005509molecular_functioncalcium ion binding
K0005515molecular_functionprotein binding
K0005543molecular_functionphospholipid binding
K0005576cellular_componentextracellular region
K0005615cellular_componentextracellular space
K0005634cellular_componentnucleus
K0005640cellular_componentnuclear outer membrane
K0005737cellular_componentcytoplasm
K0005739cellular_componentmitochondrion
K0005741cellular_componentmitochondrial outer membrane
K0005743cellular_componentmitochondrial inner membrane
K0005759cellular_componentmitochondrial matrix
K0005764cellular_componentlysosome
K0005829cellular_componentcytosol
K0005840cellular_componentribosome
K0005856cellular_componentcytoskeleton
K0005886cellular_componentplasma membrane
K0005938cellular_componentcell cortex
K0006749biological_processglutathione metabolic process
K0008017molecular_functionmicrotubule binding
K0008021cellular_componentsynaptic vesicle
K0008047molecular_functionenzyme activator activity
K0008198molecular_functionferrous iron binding
K0008270molecular_functionzinc ion binding
K0008289molecular_functionlipid binding
K0010040biological_processresponse to iron(II) ion
K0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
K0014059biological_processregulation of dopamine secretion
K0015629cellular_componentactin cytoskeleton
K0015631molecular_functiontubulin binding
K0016020cellular_componentmembrane
K0016079biological_processsynaptic vesicle exocytosis
K0016082biological_processsynaptic vesicle priming
K0016234cellular_componentinclusion body
K0016491molecular_functionoxidoreductase activity
K0019894molecular_functionkinesin binding
K0019899molecular_functionenzyme binding
K0019904molecular_functionprotein domain specific binding
K0030424cellular_componentaxon
K0030426cellular_componentgrowth cone
K0030544molecular_functionHsp70 protein binding
K0030659cellular_componentcytoplasmic vesicle membrane
K0030672cellular_componentsynaptic vesicle membrane
K0031092cellular_componentplatelet alpha granule membrane
K0031115biological_processnegative regulation of microtubule polymerization
K0031623biological_processreceptor internalization
K0031648biological_processprotein destabilization
K0032026biological_processresponse to magnesium ion
K0032496biological_processresponse to lipopolysaccharide
K0032991cellular_componentprotein-containing complex
K0034341biological_processresponse to type II interferon
K0034599biological_processcellular response to oxidative stress
K0035493biological_processSNARE complex assembly
K0035543biological_processpositive regulation of SNARE complex assembly
K0042220biological_processresponse to cocaine
K0042393molecular_functionhistone binding
K0042416biological_processdopamine biosynthetic process
K0042802molecular_functionidentical protein binding
K0043014molecular_functionalpha-tubulin binding
K0043025cellular_componentneuronal cell body
K0043065biological_processpositive regulation of apoptotic process
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K0043195cellular_componentterminal bouton
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K0043679cellular_componentaxon terminus
K0044344biological_processcellular response to fibroblast growth factor stimulus
K0045202cellular_componentsynapse
K0045807biological_processpositive regulation of endocytosis
K0045920biological_processnegative regulation of exocytosis
K0045921biological_processpositive regulation of exocytosis
K0045963biological_processnegative regulation of dopamine metabolic process
K0046872molecular_functionmetal ion binding
K0048148biological_processbehavioral response to cocaine
K0048156molecular_functiontau protein binding
K0048471cellular_componentperinuclear region of cytoplasm
K0048487molecular_functionbeta-tubulin binding
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K0048489biological_processsynaptic vesicle transport
K0050729biological_processpositive regulation of inflammatory response
K0050808biological_processsynapse organization
K0051219molecular_functionphosphoprotein binding
K0051259biological_processprotein complex oligomerization
K0051262biological_processprotein tetramerization
K0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
K0051583biological_processdopamine uptake involved in synaptic transmission
K0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
K0051612biological_processnegative regulation of serotonin uptake
K0051621biological_processregulation of norepinephrine uptake
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K0055074biological_processcalcium ion homeostasis
K0060732biological_processpositive regulation of inositol phosphate biosynthetic process
K0060961molecular_functionphospholipase D inhibitor activity
K0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
K0070507biological_processregulation of microtubule cytoskeleton organization
K0070555biological_processresponse to interleukin-1
K0070840molecular_functiondynein complex binding
K0071280biological_processcellular response to copper ion
K0071872biological_processcellular response to epinephrine stimulus
K0097413cellular_componentLewy body
K0097435biological_processsupramolecular fiber organization
K0098793cellular_componentpresynapse
K0099512cellular_componentsupramolecular fiber
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K0141108molecular_functiontransporter regulator activity
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K1903426biological_processregulation of reactive oxygen species biosynthetic process
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K1904377biological_processpositive regulation of protein localization to cell periphery
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L0005615cellular_componentextracellular space
L0005634cellular_componentnucleus
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L0005737cellular_componentcytoplasm
L0005739cellular_componentmitochondrion
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L0005759cellular_componentmitochondrial matrix
L0005764cellular_componentlysosome
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L0005840cellular_componentribosome
L0005856cellular_componentcytoskeleton
L0005886cellular_componentplasma membrane
L0005938cellular_componentcell cortex
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L0030426cellular_componentgrowth cone
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L0030659cellular_componentcytoplasmic vesicle membrane
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L0031092cellular_componentplatelet alpha granule membrane
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L0031623biological_processreceptor internalization
L0031648biological_processprotein destabilization
L0032026biological_processresponse to magnesium ion
L0032496biological_processresponse to lipopolysaccharide
L0032991cellular_componentprotein-containing complex
L0034341biological_processresponse to type II interferon
L0034599biological_processcellular response to oxidative stress
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L0043195cellular_componentterminal bouton
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L0043679cellular_componentaxon terminus
L0044344biological_processcellular response to fibroblast growth factor stimulus
L0045202cellular_componentsynapse
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L0045920biological_processnegative regulation of exocytosis
L0045921biological_processpositive regulation of exocytosis
L0045963biological_processnegative regulation of dopamine metabolic process
L0046872molecular_functionmetal ion binding
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L0048156molecular_functiontau protein binding
L0048471cellular_componentperinuclear region of cytoplasm
L0048487molecular_functionbeta-tubulin binding
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L0048489biological_processsynaptic vesicle transport
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L0050808biological_processsynapse organization
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L0051259biological_processprotein complex oligomerization
L0051262biological_processprotein tetramerization
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L0051583biological_processdopamine uptake involved in synaptic transmission
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L0051612biological_processnegative regulation of serotonin uptake
L0051621biological_processregulation of norepinephrine uptake
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L0071872biological_processcellular response to epinephrine stimulus
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M0005615cellular_componentextracellular space
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M0005640cellular_componentnuclear outer membrane
M0005737cellular_componentcytoplasm
M0005739cellular_componentmitochondrion
M0005741cellular_componentmitochondrial outer membrane
M0005743cellular_componentmitochondrial inner membrane
M0005759cellular_componentmitochondrial matrix
M0005764cellular_componentlysosome
M0005829cellular_componentcytosol
M0005840cellular_componentribosome
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M0016020cellular_componentmembrane
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M0016234cellular_componentinclusion body
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M0019899molecular_functionenzyme binding
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M0030426cellular_componentgrowth cone
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M0030659cellular_componentcytoplasmic vesicle membrane
M0030672cellular_componentsynaptic vesicle membrane
M0031092cellular_componentplatelet alpha granule membrane
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M0031623biological_processreceptor internalization
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M0032026biological_processresponse to magnesium ion
M0032496biological_processresponse to lipopolysaccharide
M0032991cellular_componentprotein-containing complex
M0034341biological_processresponse to type II interferon
M0034599biological_processcellular response to oxidative stress
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M0043195cellular_componentterminal bouton
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M0043679cellular_componentaxon terminus
M0044344biological_processcellular response to fibroblast growth factor stimulus
M0045202cellular_componentsynapse
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M0045921biological_processpositive regulation of exocytosis
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M0051262biological_processprotein tetramerization
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M0071872biological_processcellular response to epinephrine stimulus
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N0005615cellular_componentextracellular space
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N0005737cellular_componentcytoplasm
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N0030426cellular_componentgrowth cone
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N0030659cellular_componentcytoplasmic vesicle membrane
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N0031092cellular_componentplatelet alpha granule membrane
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N0031623biological_processreceptor internalization
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N0032026biological_processresponse to magnesium ion
N0032496biological_processresponse to lipopolysaccharide
N0032991cellular_componentprotein-containing complex
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N0034599biological_processcellular response to oxidative stress
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N0043195cellular_componentterminal bouton
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N0043679cellular_componentaxon terminus
N0044344biological_processcellular response to fibroblast growth factor stimulus
N0045202cellular_componentsynapse
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N0051612biological_processnegative regulation of serotonin uptake
N0051621biological_processregulation of norepinephrine uptake
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O0005615cellular_componentextracellular space
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O0005737cellular_componentcytoplasm
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O0005743cellular_componentmitochondrial inner membrane
O0005759cellular_componentmitochondrial matrix
O0005764cellular_componentlysosome
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O0005840cellular_componentribosome
O0005856cellular_componentcytoskeleton
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O0030426cellular_componentgrowth cone
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O0031092cellular_componentplatelet alpha granule membrane
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O0032496biological_processresponse to lipopolysaccharide
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O0043195cellular_componentterminal bouton
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O0043679cellular_componentaxon terminus
O0044344biological_processcellular response to fibroblast growth factor stimulus
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O0051262biological_processprotein tetramerization
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O0051612biological_processnegative regulation of serotonin uptake
O0051621biological_processregulation of norepinephrine uptake
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O0055074biological_processcalcium ion homeostasis
O0060732biological_processpositive regulation of inositol phosphate biosynthetic process
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O0070555biological_processresponse to interleukin-1
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O0071872biological_processcellular response to epinephrine stimulus
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O0098793cellular_componentpresynapse
O0099512cellular_componentsupramolecular fiber
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O1905606biological_processregulation of presynapse assembly
O1990000biological_processamyloid fibril formation
O2000377biological_processregulation of reactive oxygen species metabolic process
P0000122biological_processnegative regulation of transcription by RNA polymerase II
P0000149molecular_functionSNARE binding
P0000287molecular_functionmagnesium ion binding
P0000976molecular_functiontranscription cis-regulatory region binding
P0001774biological_processmicroglial cell activation
P0001921biological_processpositive regulation of receptor recycling
P0001963biological_processsynaptic transmission, dopaminergic
P0003779molecular_functionactin binding
P0004857molecular_functionenzyme inhibitor activity
P0004860molecular_functionprotein kinase inhibitor activity
P0004869molecular_functioncysteine-type endopeptidase inhibitor activity
P0005504molecular_functionfatty acid binding
P0005507molecular_functioncopper ion binding
P0005509molecular_functioncalcium ion binding
P0005515molecular_functionprotein binding
P0005543molecular_functionphospholipid binding
P0005576cellular_componentextracellular region
P0005615cellular_componentextracellular space
P0005634cellular_componentnucleus
P0005640cellular_componentnuclear outer membrane
P0005737cellular_componentcytoplasm
P0005739cellular_componentmitochondrion
P0005741cellular_componentmitochondrial outer membrane
P0005743cellular_componentmitochondrial inner membrane
P0005759cellular_componentmitochondrial matrix
P0005764cellular_componentlysosome
P0005829cellular_componentcytosol
P0005840cellular_componentribosome
P0005856cellular_componentcytoskeleton
P0005886cellular_componentplasma membrane
P0005938cellular_componentcell cortex
P0006749biological_processglutathione metabolic process
P0008017molecular_functionmicrotubule binding
P0008021cellular_componentsynaptic vesicle
P0008047molecular_functionenzyme activator activity
P0008198molecular_functionferrous iron binding
P0008270molecular_functionzinc ion binding
P0008289molecular_functionlipid binding
P0010040biological_processresponse to iron(II) ion
P0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
P0014059biological_processregulation of dopamine secretion
P0015629cellular_componentactin cytoskeleton
P0015631molecular_functiontubulin binding
P0016020cellular_componentmembrane
P0016079biological_processsynaptic vesicle exocytosis
P0016082biological_processsynaptic vesicle priming
P0016234cellular_componentinclusion body
P0016491molecular_functionoxidoreductase activity
P0019894molecular_functionkinesin binding
P0019899molecular_functionenzyme binding
P0019904molecular_functionprotein domain specific binding
P0030424cellular_componentaxon
P0030426cellular_componentgrowth cone
P0030544molecular_functionHsp70 protein binding
P0030659cellular_componentcytoplasmic vesicle membrane
P0030672cellular_componentsynaptic vesicle membrane
P0031092cellular_componentplatelet alpha granule membrane
P0031115biological_processnegative regulation of microtubule polymerization
P0031623biological_processreceptor internalization
P0031648biological_processprotein destabilization
P0032026biological_processresponse to magnesium ion
P0032496biological_processresponse to lipopolysaccharide
P0032991cellular_componentprotein-containing complex
P0034341biological_processresponse to type II interferon
P0034599biological_processcellular response to oxidative stress
P0035493biological_processSNARE complex assembly
P0035543biological_processpositive regulation of SNARE complex assembly
P0042220biological_processresponse to cocaine
P0042393molecular_functionhistone binding
P0042416biological_processdopamine biosynthetic process
P0042802molecular_functionidentical protein binding
P0043014molecular_functionalpha-tubulin binding
P0043025cellular_componentneuronal cell body
P0043065biological_processpositive regulation of apoptotic process
P0043066biological_processnegative regulation of apoptotic process
P0043195cellular_componentterminal bouton
P0043274molecular_functionphospholipase binding
P0043524biological_processnegative regulation of neuron apoptotic process
P0043679cellular_componentaxon terminus
P0044344biological_processcellular response to fibroblast growth factor stimulus
P0045202cellular_componentsynapse
P0045807biological_processpositive regulation of endocytosis
P0045920biological_processnegative regulation of exocytosis
P0045921biological_processpositive regulation of exocytosis
P0045963biological_processnegative regulation of dopamine metabolic process
P0046872molecular_functionmetal ion binding
P0048148biological_processbehavioral response to cocaine
P0048156molecular_functiontau protein binding
P0048471cellular_componentperinuclear region of cytoplasm
P0048487molecular_functionbeta-tubulin binding
P0048488biological_processsynaptic vesicle endocytosis
P0048489biological_processsynaptic vesicle transport
P0050729biological_processpositive regulation of inflammatory response
P0050808biological_processsynapse organization
P0051219molecular_functionphosphoprotein binding
P0051259biological_processprotein complex oligomerization
P0051262biological_processprotein tetramerization
P0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
P0051583biological_processdopamine uptake involved in synaptic transmission
P0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
P0051612biological_processnegative regulation of serotonin uptake
P0051621biological_processregulation of norepinephrine uptake
P0051622biological_processnegative regulation of norepinephrine uptake
P0055074biological_processcalcium ion homeostasis
P0060732biological_processpositive regulation of inositol phosphate biosynthetic process
P0060961molecular_functionphospholipase D inhibitor activity
P0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
P0070507biological_processregulation of microtubule cytoskeleton organization
P0070555biological_processresponse to interleukin-1
P0070840molecular_functiondynein complex binding
P0071280biological_processcellular response to copper ion
P0071872biological_processcellular response to epinephrine stimulus
P0097413cellular_componentLewy body
P0097435biological_processsupramolecular fiber organization
P0098793cellular_componentpresynapse
P0099512cellular_componentsupramolecular fiber
P0140311molecular_functionprotein sequestering activity
P0141108molecular_functiontransporter regulator activity
P1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
P1903136molecular_functioncuprous ion binding
P1903285biological_processpositive regulation of hydrogen peroxide catabolic process
P1903421biological_processregulation of synaptic vesicle recycling
P1903426biological_processregulation of reactive oxygen species biosynthetic process
P1904307biological_processresponse to desipramine
P1904377biological_processpositive regulation of protein localization to cell periphery
P1904715biological_processnegative regulation of chaperone-mediated autophagy
P1905606biological_processregulation of presynapse assembly
P1990000biological_processamyloid fibril formation
P2000377biological_processregulation of reactive oxygen species metabolic process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues140
DetailsRepeat: {"description":"3; approximate"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues100
DetailsRepeat: {"description":"4"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues10
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues10
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"10617630","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

246704

PDB entries from 2025-12-24

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