9QPK
E.coli TalB mutant E96Q, F178Y, R300E
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Schiff-base intermediate with substrate","evidences":[{"source":"PubMed","id":"11298760","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 148 |
| Chain | Residue | Details |
| A | ASP17 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | GLN96 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | LYS132 | covalently attached, electron pair acceptor, electron pair donor, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| A | THR156 | electrostatic stabiliser, hydrogen bond donor |
| A | TYR178 | steric role |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 148 |
| Chain | Residue | Details |
| B | ASP17 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | GLN96 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | LYS132 | covalently attached, electron pair acceptor, electron pair donor, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| B | THR156 | electrostatic stabiliser, hydrogen bond donor |
| B | TYR178 | steric role |
| site_id | MCSA3 |
| Number of Residues | 5 |
| Details | M-CSA 148 |
| Chain | Residue | Details |
| C | ASP17 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| C | GLN96 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| C | LYS132 | covalently attached, electron pair acceptor, electron pair donor, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| C | THR156 | electrostatic stabiliser, hydrogen bond donor |
| C | TYR178 | steric role |
| site_id | MCSA4 |
| Number of Residues | 5 |
| Details | M-CSA 148 |
| Chain | Residue | Details |
| D | ASP17 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| D | GLN96 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| D | LYS132 | covalently attached, electron pair acceptor, electron pair donor, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| D | THR156 | electrostatic stabiliser, hydrogen bond donor |
| D | TYR178 | steric role |
