9QNO

Ternary complex of the human 20S proteasome in complex with Importin-9 and two homodimers of Akirin-2 - focussed refinement on Importin-9 and Akirin-2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005635	cellular_component	nuclear envelope
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006606	biological_process	protein import into nucleus
A	0016020	cellular_component	membrane
A	0031144	biological_process	proteasome localization
A	0042393	molecular_function	histone binding
A	0061608	molecular_function	nuclear import signal receptor activity
A	0140713	molecular_function	histone chaperone activity
D	0000785	cellular_component	chromatin
D	0002821	biological_process	positive regulation of adaptive immune response
D	0003712	molecular_function	transcription coregulator activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0006606	biological_process	protein import into nucleus
D	0009792	biological_process	embryo development ending in birth or egg hatching
D	0016020	cellular_component	membrane
D	0017053	cellular_component	transcription repressor complex
D	0019899	molecular_function	enzyme binding
D	0021987	biological_process	cerebral cortex development
D	0030674	molecular_function	protein-macromolecule adaptor activity
D	0031144	biological_process	proteasome localization
D	0032755	biological_process	positive regulation of interleukin-6 production
D	0042742	biological_process	defense response to bacterium
D	0042802	molecular_function	identical protein binding
D	0045089	biological_process	positive regulation of innate immune response
D	0045944	biological_process	positive regulation of transcription by RNA polymerase II
D	0050871	biological_process	positive regulation of B cell activation
D	0051147	biological_process	regulation of muscle cell differentiation
D	0071630	biological_process	nuclear protein quality control by the ubiquitin-proteasome system
E	0000785	cellular_component	chromatin
E	0002821	biological_process	positive regulation of adaptive immune response
E	0003712	molecular_function	transcription coregulator activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0006606	biological_process	protein import into nucleus
E	0009792	biological_process	embryo development ending in birth or egg hatching
E	0016020	cellular_component	membrane
E	0017053	cellular_component	transcription repressor complex
E	0019899	molecular_function	enzyme binding
E	0021987	biological_process	cerebral cortex development
E	0030674	molecular_function	protein-macromolecule adaptor activity
E	0031144	biological_process	proteasome localization
E	0032755	biological_process	positive regulation of interleukin-6 production
E	0042742	biological_process	defense response to bacterium
E	0042802	molecular_function	identical protein binding
E	0045089	biological_process	positive regulation of innate immune response
E	0045944	biological_process	positive regulation of transcription by RNA polymerase II
E	0050871	biological_process	positive regulation of B cell activation
E	0051147	biological_process	regulation of muscle cell differentiation
E	0071630	biological_process	nuclear protein quality control by the ubiquitin-proteasome system

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	76
Details	Domain: {"description":"Importin N-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00115","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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