9QDQ

Cryo-EM structure of Upf1-Nmd4-Ebs1 in complex with RNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
A	0000956	biological_process	nuclear-transcribed mRNA catabolic process
A	0003678	molecular_function	DNA helicase activity
A	0003697	molecular_function	single-stranded DNA binding
A	0003723	molecular_function	RNA binding
A	0003724	molecular_function	RNA helicase activity
A	0003729	molecular_function	mRNA binding
A	0004386	molecular_function	helicase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006310	biological_process	DNA recombination
A	0006449	biological_process	regulation of translational termination
A	0008270	molecular_function	zinc ion binding
A	0008298	biological_process	intracellular mRNA localization
A	0016567	biological_process	protein ubiquitination
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0030466	biological_process	silent mating-type cassette heterochromatin formation
A	0036121	molecular_function	double-stranded DNA helicase activity
A	0043024	molecular_function	ribosomal small subunit binding
A	0046872	molecular_function	metal ion binding
A	0070478	biological_process	nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
A	0071026	biological_process	cytoplasmic RNA surveillance
B	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
B	0000781	cellular_component	chromosome, telomeric region
B	0000932	cellular_component	P-body
B	0003674	molecular_function	molecular_function
B	0005634	cellular_component	nucleus
B	0005697	cellular_component	telomerase holoenzyme complex
B	0005737	cellular_component	cytoplasm
B	0006310	biological_process	DNA recombination
B	0017148	biological_process	negative regulation of translation
B	0042162	molecular_function	telomeric DNA binding
B	0070034	molecular_function	telomerase RNA binding
C	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
C	0003674	molecular_function	molecular_function
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Region: {"description":"C3H","evidences":[{"source":"PROSITE-ProRule","id":"PRU01341","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	28
Details	Region: {"description":"CC/SHH/C","evidences":[{"source":"PROSITE-ProRule","id":"PRU01341","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	30
Details	Region: {"description":"C4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01341","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01341","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q92900","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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