9Q41
Crystal Structure of Human Apo Spermidine Synthase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004766 | molecular_function | spermidine synthase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006595 | biological_process | polyamine metabolic process |
| A | 0006596 | biological_process | polyamine biosynthetic process |
| A | 0006597 | biological_process | spermine biosynthetic process |
| A | 0008295 | biological_process | spermidine biosynthetic process |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| B | 0004766 | molecular_function | spermidine synthase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006595 | biological_process | polyamine metabolic process |
| B | 0006596 | biological_process | polyamine biosynthetic process |
| B | 0006597 | biological_process | spermine biosynthetic process |
| B | 0008295 | biological_process | spermidine biosynthetic process |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PROSITE/UniProt
| site_id | PS01330 |
| Number of Residues | 14 |
| Details | PABS_1 Polyamine biosynthesis (PABS) domain signature. VLIIGGGdGgvLrE |
| Chain | Residue | Details |
| A | VAL97-GLU110 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00354","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17585781","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2O07","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17585781","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2O05","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2O06","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2O07","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RW9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17585781","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2O0L","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17585781","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2O06","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
