9PR5

Cryo-EM structure of the human inward-rectifier potassium 7.1 channel (Kir7.1) extended state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005242	molecular_function	inward rectifier potassium channel activity
A	0005267	molecular_function	potassium channel activity
A	0005886	cellular_component	plasma membrane
A	0006813	biological_process	potassium ion transport
A	0016020	cellular_component	membrane
A	0030007	biological_process	intracellular potassium ion homeostasis
A	0034702	cellular_component	monoatomic ion channel complex
A	0042391	biological_process	regulation of membrane potential
A	1990573	biological_process	potassium ion import across plasma membrane
B	0005242	molecular_function	inward rectifier potassium channel activity
B	0005267	molecular_function	potassium channel activity
B	0005886	cellular_component	plasma membrane
B	0006813	biological_process	potassium ion transport
B	0016020	cellular_component	membrane
B	0030007	biological_process	intracellular potassium ion homeostasis
B	0034702	cellular_component	monoatomic ion channel complex
B	0042391	biological_process	regulation of membrane potential
B	1990573	biological_process	potassium ion import across plasma membrane
C	0005242	molecular_function	inward rectifier potassium channel activity
C	0005267	molecular_function	potassium channel activity
C	0005886	cellular_component	plasma membrane
C	0006813	biological_process	potassium ion transport
C	0016020	cellular_component	membrane
C	0030007	biological_process	intracellular potassium ion homeostasis
C	0034702	cellular_component	monoatomic ion channel complex
C	0042391	biological_process	regulation of membrane potential
C	1990573	biological_process	potassium ion import across plasma membrane
D	0005242	molecular_function	inward rectifier potassium channel activity
D	0005267	molecular_function	potassium channel activity
D	0005886	cellular_component	plasma membrane
D	0006813	biological_process	potassium ion transport
D	0016020	cellular_component	membrane
D	0030007	biological_process	intracellular potassium ion homeostasis
D	0034702	cellular_component	monoatomic ion channel complex
D	0042391	biological_process	regulation of membrane potential
D	1990573	biological_process	potassium ion import across plasma membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	104
Details	Transmembrane: {"description":"Helical; Name=M1","evidences":[{"source":"UniProtKB","id":"P49655","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	140
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"UniProtKB","id":"P49655","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	64
Details	Intramembrane: {"description":"Helical; Pore-forming","evidences":[{"source":"UniProtKB","id":"P49655","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	100
Details	Transmembrane: {"description":"Helical; Name=M2","evidences":[{"source":"UniProtKB","id":"P49655","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	20
Details	Motif: {"description":"Selectivity filter","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Site: {"description":"Role in the control of polyamine-mediated channel gating and in the blocking by intracellular magnesium","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine; by PKC","evidences":[{"source":"PubMed","id":"18976636","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine; by PKA","evidences":[{"source":"PubMed","id":"18976636","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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