9PKZ

Alpha1/Beta Heteromeric Glycine receptor in the presence of 0.200 mM strychnine and 0.02 mM ivermectin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0006821	biological_process	chloride transport
A	0016020	cellular_component	membrane
A	0016594	molecular_function	glycine binding
A	0016934	molecular_function	extracellularly glycine-gated chloride channel activity
A	0022824	molecular_function	transmitter-gated monoatomic ion channel activity
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0045211	cellular_component	postsynaptic membrane
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0006821	biological_process	chloride transport
B	0016020	cellular_component	membrane
B	0016594	molecular_function	glycine binding
B	0016934	molecular_function	extracellularly glycine-gated chloride channel activity
B	0022824	molecular_function	transmitter-gated monoatomic ion channel activity
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0045211	cellular_component	postsynaptic membrane
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0005886	cellular_component	plasma membrane
C	0006811	biological_process	monoatomic ion transport
C	0006821	biological_process	chloride transport
C	0016020	cellular_component	membrane
C	0016594	molecular_function	glycine binding
C	0016934	molecular_function	extracellularly glycine-gated chloride channel activity
C	0022824	molecular_function	transmitter-gated monoatomic ion channel activity
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0045211	cellular_component	postsynaptic membrane
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0005886	cellular_component	plasma membrane
D	0006811	biological_process	monoatomic ion transport
D	0006821	biological_process	chloride transport
D	0016020	cellular_component	membrane
D	0016594	molecular_function	glycine binding
D	0016934	molecular_function	extracellularly glycine-gated chloride channel activity
D	0022824	molecular_function	transmitter-gated monoatomic ion channel activity
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0045211	cellular_component	postsynaptic membrane
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0005737	cellular_component	cytoplasm
E	0006811	biological_process	monoatomic ion transport
E	0006821	biological_process	chloride transport
E	0008104	biological_process	intracellular protein localization
E	0016020	cellular_component	membrane
E	0016933	molecular_function	extracellularly glycine-gated ion channel activity
E	0016934	molecular_function	extracellularly glycine-gated chloride channel activity
E	0030425	cellular_component	dendrite
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0045211	cellular_component	postsynaptic membrane
E	0060079	biological_process	excitatory postsynaptic potential
E	1902476	biological_process	chloride transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00236
Number of Residues	15
Details	NEUROTR_ION_CHANNEL Neurotransmitter-gated ion-channels signature. CpLdLtlFPmDtqrC

Chain	Residue	Details
E	CYS182-CYS196
A	CYS162-CYS176

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