Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9PJ8

C. acnes 70S ribosome bound to Sarecycline

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0005737	cellular_component	cytoplasm
0	0006412	biological_process	translation
0	0008270	molecular_function	zinc ion binding
0	0019843	molecular_function	rRNA binding
1	0006412	biological_process	translation
2	0003735	molecular_function	structural constituent of ribosome
2	0006412	biological_process	translation
2	0015934	cellular_component	large ribosomal subunit
2	0022625	cellular_component	cytosolic large ribosomal subunit
3	0005737	cellular_component	cytoplasm
3	0006412	biological_process	translation
3	0008270	molecular_function	zinc ion binding
3	0019843	molecular_function	rRNA binding
4	0006412	biological_process	translation
B	0003735	molecular_function	structural constituent of ribosome
B	0006412	biological_process	translation
B	0022627	cellular_component	cytosolic small ribosomal subunit
c	0002181	biological_process	cytoplasmic translation
c	0003723	molecular_function	RNA binding
c	0003735	molecular_function	structural constituent of ribosome
c	0006412	biological_process	translation
c	0015934	cellular_component	large ribosomal subunit
c	0019843	molecular_function	rRNA binding
d	0003735	molecular_function	structural constituent of ribosome
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
d	0019843	molecular_function	rRNA binding
d	0022625	cellular_component	cytosolic large ribosomal subunit
D	0003735	molecular_function	structural constituent of ribosome
D	0006412	biological_process	translation
D	0015935	cellular_component	small ribosomal subunit
D	0019843	molecular_function	rRNA binding
D	0042274	biological_process	ribosomal small subunit biogenesis
e	0003735	molecular_function	structural constituent of ribosome
e	0006412	biological_process	translation
e	0019843	molecular_function	rRNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005737	cellular_component	cytoplasm
E	0006412	biological_process	translation
E	0019843	molecular_function	rRNA binding
E	0042254	biological_process	ribosome biogenesis
E	1990904	cellular_component	ribonucleoprotein complex
f	0000049	molecular_function	tRNA binding
f	0006412	biological_process	translation
f	0019843	molecular_function	rRNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005737	cellular_component	cytoplasm
F	0006412	biological_process	translation
F	0019843	molecular_function	rRNA binding
F	0070181	molecular_function	small ribosomal subunit rRNA binding
g	0002181	biological_process	cytoplasmic translation
g	0003723	molecular_function	RNA binding
g	0003735	molecular_function	structural constituent of ribosome
g	0006412	biological_process	translation
g	0019843	molecular_function	rRNA binding
g	0022625	cellular_component	cytosolic large ribosomal subunit
G	0003723	molecular_function	RNA binding
G	0003729	molecular_function	mRNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0006412	biological_process	translation
G	0019843	molecular_function	rRNA binding
G	0022627	cellular_component	cytosolic small ribosomal subunit
H	0005737	cellular_component	cytoplasm
H	0006412	biological_process	translation
H	0019843	molecular_function	rRNA binding
i	0003729	molecular_function	mRNA binding
i	0003735	molecular_function	structural constituent of ribosome
i	0005840	cellular_component	ribosome
i	0006412	biological_process	translation
i	0017148	biological_process	negative regulation of translation
i	0022625	cellular_component	cytosolic large ribosomal subunit
I	0000049	molecular_function	tRNA binding
I	0006412	biological_process	translation
I	0019843	molecular_function	rRNA binding
j	0003735	molecular_function	structural constituent of ribosome
j	0006412	biological_process	translation
j	0019843	molecular_function	rRNA binding
j	0022625	cellular_component	cytosolic large ribosomal subunit
j	0070180	molecular_function	large ribosomal subunit rRNA binding
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005737	cellular_component	cytoplasm
J	0006412	biological_process	translation
J	0015935	cellular_component	small ribosomal subunit
k	0003735	molecular_function	structural constituent of ribosome
k	0006412	biological_process	translation
k	0019843	molecular_function	rRNA binding
k	0022625	cellular_component	cytosolic large ribosomal subunit
K	0006412	biological_process	translation
K	0019843	molecular_function	rRNA binding
l	0003735	molecular_function	structural constituent of ribosome
l	0006412	biological_process	translation
l	0019843	molecular_function	rRNA binding
l	0022625	cellular_component	cytosolic large ribosomal subunit
L	0000049	molecular_function	tRNA binding
L	0006412	biological_process	translation
L	0019843	molecular_function	rRNA binding
m	0003735	molecular_function	structural constituent of ribosome
m	0006412	biological_process	translation
m	0015934	cellular_component	large ribosomal subunit
m	0022625	cellular_component	cytosolic large ribosomal subunit
M	0000049	molecular_function	tRNA binding
M	0005737	cellular_component	cytoplasm
M	0006412	biological_process	translation
n	0005737	cellular_component	cytoplasm
n	0006412	biological_process	translation
n	0008097	molecular_function	5S rRNA binding
n	0019843	molecular_function	rRNA binding
n	0022625	cellular_component	cytosolic large ribosomal subunit
N	0000049	molecular_function	tRNA binding
N	0005829	cellular_component	cytosol
N	0006412	biological_process	translation
N	0015935	cellular_component	small ribosomal subunit
N	0019843	molecular_function	rRNA binding
o	0003735	molecular_function	structural constituent of ribosome
o	0006412	biological_process	translation
o	0022625	cellular_component	cytosolic large ribosomal subunit
O	0005737	cellular_component	cytoplasm
O	0006412	biological_process	translation
O	0019843	molecular_function	rRNA binding
O	0022627	cellular_component	cytosolic small ribosomal subunit
p	0000027	biological_process	ribosomal large subunit assembly
p	0019843	molecular_function	rRNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005737	cellular_component	cytoplasm
P	0006412	biological_process	translation
P	0015935	cellular_component	small ribosomal subunit
q	0003735	molecular_function	structural constituent of ribosome
q	0005737	cellular_component	cytoplasm
q	0006412	biological_process	translation
q	0019843	molecular_function	rRNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0006412	biological_process	translation
Q	0019843	molecular_function	rRNA binding
Q	0022627	cellular_component	cytosolic small ribosomal subunit
r	0003735	molecular_function	structural constituent of ribosome
r	0006412	biological_process	translation
r	0015934	cellular_component	large ribosomal subunit
r	0019843	molecular_function	rRNA binding
r	0022625	cellular_component	cytosolic large ribosomal subunit
R	0003735	molecular_function	structural constituent of ribosome
R	0006412	biological_process	translation
R	0019843	molecular_function	rRNA binding
R	0022627	cellular_component	cytosolic small ribosomal subunit
R	0070181	molecular_function	small ribosomal subunit rRNA binding
s	0006412	biological_process	translation
s	0019843	molecular_function	rRNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0006412	biological_process	translation
S	0008270	molecular_function	zinc ion binding
S	0015935	cellular_component	small ribosomal subunit
S	0019843	molecular_function	rRNA binding
t	0006412	biological_process	translation
t	0019843	molecular_function	rRNA binding
T	0005829	cellular_component	cytosol
T	0006412	biological_process	translation
T	0015935	cellular_component	small ribosomal subunit
T	0019843	molecular_function	rRNA binding
T	0070181	molecular_function	small ribosomal subunit rRNA binding
u	0003723	molecular_function	RNA binding
u	0006412	biological_process	translation
u	0008097	molecular_function	5S rRNA binding
u	0022625	cellular_component	cytosolic large ribosomal subunit
U	0000028	biological_process	ribosomal small subunit assembly
U	0003735	molecular_function	structural constituent of ribosome
U	0005737	cellular_component	cytoplasm
U	0006412	biological_process	translation
U	0019843	molecular_function	rRNA binding
v	0003735	molecular_function	structural constituent of ribosome
v	0006412	biological_process	translation
v	0022625	cellular_component	cytosolic large ribosomal subunit
w	0006412	biological_process	translation
w	0008270	molecular_function	zinc ion binding
w	0019843	molecular_function	rRNA binding
x	0006412	biological_process	translation
x	0022625	cellular_component	cytosolic large ribosomal subunit
y	0006412	biological_process	translation
y	0022625	cellular_component	cytosolic large ribosomal subunit
z	0006412	biological_process	translation

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtvkshrrp.DGsyikFdeNaaVL

Chain	Residue	Details
j	ALA60-LEU86

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. SpLvsqLVskilldGKKtvaqnIVytA

Chain	Residue	Details
I	SER20-ALA46

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GiaIISTSqGLLtdkqAH

Chain	Residue	Details
H	GLY105-HIS122

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. IrSLgaV.GLeIgpisDvTPvPHN

Chain	Residue	Details
K	ILE103-ASN125

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR

Chain	Residue	Details
L	LYS43-ARG50

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDrVrImEtRPLS

Chain	Residue	Details
Q	GLY63-SER75

site_id	PS00057
Number of Residues	24
Details	RIBOSOMAL_S18 Ribosomal protein S18 signature. VDYkd.TalLrkFISEr.GKIrarRV

Chain	Residue	Details
R	VAL21-VAL44

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. DGRkhvpvfVtesmVGhkLGEFapT

Chain	Residue	Details
U	ASP53-THR77

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGvtGQagAlrlGiARAL

Chain	Residue	Details
J	GLY111-LEU129

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. VtrtGAkvaGPVpLPT

Chain	Residue	Details
M	VAL29-THR44

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. LteHLkvhKgDhhSrrgLmlMvgqrrrLlnY

Chain	Residue	Details
O	LEU37-TYR67

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RriRpRAkGSasrilkrsAHITVvV

Chain	Residue	Details
r	ARG100-VAL124

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGVVmNPiD

Chain	Residue	Details
c	PRO219-ASP230

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FsesdfvDvtGtSkGKGtaGvmkR

Chain	Residue	Details
d	PHE107-ARG130

site_id	PS00525
Number of Residues	9
Details	RIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PEpYKGKGV

Chain	Residue	Details
g	PRO156-VAL164

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CqrcgrphsvyrkFGLCRiCLR

Chain	Residue	Details
S	ARG23-ARG45

site_id	PS00548
Number of Residues	35
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. SRsegyreGrVplHt..LradIDygffearTtfGriG

Chain	Residue	Details
G	SER162-GLY196

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. NTARLReVRKDIARV

Chain	Residue	Details
x	ASN42-VAL56

site_id	PS00582
Number of Residues	20
Details	RIBOSOMAL_L33 Ribosomal protein L33 signature. YiTkKNrrnnPdrMEmaKFC

Chain	Residue	Details
0	TYR24-CYS43

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRrfsFtAlvVVGDge.GsVGvGygkak.EVpa.AI

Chain	Residue	Details
E	GLY51-ILE83

site_id	PS00586
Number of Residues	12
Details	RIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRgGKVWINVYP

Chain	Residue	Details
l	LYS59-PRO70

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LEsRLdnvVYRaglAaTrrqARqMV

Chain	Residue	Details
D	LEU89-VAL113

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. QGrRHrsGlpVRGQ

Chain	Residue	Details
N	GLN88-GLN101

site_id	PS00701
Number of Residues	12
Details	RIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGsGKGtpewW

Chain	Residue	Details
l	ARG82-TRP93

site_id	PS00732
Number of Residues	10
Details	RIBOSOMAL_S16 Ribosomal protein S16 signature. TkIRLKRLGK

Chain	Residue	Details
P	THR3-LYS12

site_id	PS00784
Number of Residues	20
Details	RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTFQpsnrrRarnh.GFrsR

Chain	Residue	Details
1	LYS2-ARG21

site_id	PS00828
Number of Residues	26
Details	RIBOSOMAL_L36 Ribosomal protein L36 signature. CdkCkvIrRhgrVmViCdnp.RHkQrQ

Chain	Residue	Details
3	CYS11-GLN36

site_id	PS00831
Number of Residues	15
Details	RIBOSOMAL_L27 Ribosomal protein L27 signature. GeIIvRQRGthfhpG

Chain	Residue	Details
v	GLY34-GLY48

site_id	PS00937
Number of Residues	17
Details	RIBOSOMAL_L20 Ribosomal protein L20 signature. KgdfRsLWIQRINaasR

Chain	Residue	Details
p	LYS54-ARG70

site_id	PS01015
Number of Residues	16
Details	RIBOSOMAL_L19 Ribosomal protein L19 signature. VdRhGAVR.RAKLYYLR

Chain	Residue	Details
o	VAL86-ARG101

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. GDrVkVIaGndKGai.GeV

Chain	Residue	Details
t	GLY9-VAL26

site_id	PS01143
Number of Residues	22
Details	RIBOSOMAL_L31 Ribosomal protein L31 signature. DVcskcHPFYTgkqkildag....GR

Chain	Residue	Details
4	ASP36-ARG57

site_id	PS01169
Number of Residues	23
Details	RIBOSOMAL_L21 Ribosomal protein L21 signature. IrilKyknKTgykkrqGHRQkyT

Chain	Residue	Details
q	ILE71-THR93

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)