9PFT

Cryo-EM structure of the respiratory syncytial virus polymerase (L:P) in pre-translocation elongation state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0001172	biological_process	RNA-templated transcription
A	0003824	molecular_function	catalytic activity
A	0003924	molecular_function	GTPase activity
A	0003968	molecular_function	RNA-directed RNA polymerase activity
A	0005524	molecular_function	ATP binding
A	0006370	biological_process	7-methylguanosine mRNA capping
A	0006397	biological_process	mRNA processing
A	0008168	molecular_function	methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0016787	molecular_function	hydrolase activity
A	0030430	cellular_component	host cell cytoplasm
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0039689	biological_process	negative stranded viral RNA replication
A	0046872	molecular_function	metal ion binding
A	0062105	molecular_function	RNA 2'-O-methyltransferase activity
A	0106005	biological_process	RNA 5'-cap (guanine-N7)-methylation
B	0001172	biological_process	RNA-templated transcription
B	0030430	cellular_component	host cell cytoplasm
C	0001172	biological_process	RNA-templated transcription
C	0030430	cellular_component	host cell cytoplasm
D	0001172	biological_process	RNA-templated transcription
D	0030430	cellular_component	host cell cytoplasm
E	0001172	biological_process	RNA-templated transcription
E	0030430	cellular_component	host cell cytoplasm

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	184
Details	Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Nucleophile; for GDP polyribonucleotidyltransferase activity","evidences":[{"source":"UniProtKB","id":"P03523","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details