9PFG

Min22bin20S complex (NSF-alphaSNAP-2:2 syntaxin-1a H3:SNAP-25 SN1), 4:2:2 alphaSNAP-syntaxin-1a H3-SNAP-25 SN1 subcomplex local refinement, non-hydrolyzing, class 28

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0000149	molecular_function	SNARE binding
E	0005483	molecular_function	soluble NSF attachment protein activity
E	0005515	molecular_function	protein binding
E	0005739	cellular_component	mitochondrion
E	0005886	cellular_component	plasma membrane
E	0006886	biological_process	intracellular protein transport
E	0007420	biological_process	brain development
E	0008021	cellular_component	synaptic vesicle
E	0010807	biological_process	regulation of synaptic vesicle priming
E	0015031	biological_process	protein transport
E	0016082	biological_process	synaptic vesicle priming
E	0016192	biological_process	vesicle-mediated transport
E	0019905	molecular_function	syntaxin binding
E	0030182	biological_process	neuron differentiation
E	0030425	cellular_component	dendrite
E	0031410	cellular_component	cytoplasmic vesicle
E	0031594	cellular_component	neuromuscular junction
E	0032781	biological_process	positive regulation of ATP-dependent activity
E	0032984	biological_process	protein-containing complex disassembly
E	0035249	biological_process	synaptic transmission, glutamatergic
E	0035494	biological_process	SNARE complex disassembly
E	0042599	cellular_component	lamellar body
E	0042734	cellular_component	presynaptic membrane
E	0043195	cellular_component	terminal bouton
E	0043204	cellular_component	perikaryon
E	0044877	molecular_function	protein-containing complex binding
E	0045176	biological_process	apical protein localization
E	0045211	cellular_component	postsynaptic membrane
E	0048787	cellular_component	presynaptic active zone membrane
E	0055093	biological_process	response to hyperoxia
E	0061025	biological_process	membrane fusion
E	0070044	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a complex
E	0097060	cellular_component	synaptic membrane
E	0098793	cellular_component	presynapse
E	0098794	cellular_component	postsynapse
E	0098978	cellular_component	glutamatergic synapse
F	0000149	molecular_function	SNARE binding
F	0005483	molecular_function	soluble NSF attachment protein activity
F	0005515	molecular_function	protein binding
F	0005739	cellular_component	mitochondrion
F	0005886	cellular_component	plasma membrane
F	0006886	biological_process	intracellular protein transport
F	0007420	biological_process	brain development
F	0008021	cellular_component	synaptic vesicle
F	0010807	biological_process	regulation of synaptic vesicle priming
F	0015031	biological_process	protein transport
F	0016082	biological_process	synaptic vesicle priming
F	0016192	biological_process	vesicle-mediated transport
F	0019905	molecular_function	syntaxin binding
F	0030182	biological_process	neuron differentiation
F	0030425	cellular_component	dendrite
F	0031410	cellular_component	cytoplasmic vesicle
F	0031594	cellular_component	neuromuscular junction
F	0032781	biological_process	positive regulation of ATP-dependent activity
F	0032984	biological_process	protein-containing complex disassembly
F	0035249	biological_process	synaptic transmission, glutamatergic
F	0035494	biological_process	SNARE complex disassembly
F	0042599	cellular_component	lamellar body
F	0042734	cellular_component	presynaptic membrane
F	0043195	cellular_component	terminal bouton
F	0043204	cellular_component	perikaryon
F	0044877	molecular_function	protein-containing complex binding
F	0045176	biological_process	apical protein localization
F	0045211	cellular_component	postsynaptic membrane
F	0048787	cellular_component	presynaptic active zone membrane
F	0055093	biological_process	response to hyperoxia
F	0061025	biological_process	membrane fusion
F	0070044	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a complex
F	0097060	cellular_component	synaptic membrane
F	0098793	cellular_component	presynapse
F	0098794	cellular_component	postsynapse
F	0098978	cellular_component	glutamatergic synapse
G	0000149	molecular_function	SNARE binding
G	0005483	molecular_function	soluble NSF attachment protein activity
G	0005515	molecular_function	protein binding
G	0005739	cellular_component	mitochondrion
G	0005886	cellular_component	plasma membrane
G	0006886	biological_process	intracellular protein transport
G	0007420	biological_process	brain development
G	0008021	cellular_component	synaptic vesicle
G	0010807	biological_process	regulation of synaptic vesicle priming
G	0015031	biological_process	protein transport
G	0016082	biological_process	synaptic vesicle priming
G	0016192	biological_process	vesicle-mediated transport
G	0019905	molecular_function	syntaxin binding
G	0030182	biological_process	neuron differentiation
G	0030425	cellular_component	dendrite
G	0031410	cellular_component	cytoplasmic vesicle
G	0031594	cellular_component	neuromuscular junction
G	0032781	biological_process	positive regulation of ATP-dependent activity
G	0032984	biological_process	protein-containing complex disassembly
G	0035249	biological_process	synaptic transmission, glutamatergic
G	0035494	biological_process	SNARE complex disassembly
G	0042599	cellular_component	lamellar body
G	0042734	cellular_component	presynaptic membrane
G	0043195	cellular_component	terminal bouton
G	0043204	cellular_component	perikaryon
G	0044877	molecular_function	protein-containing complex binding
G	0045176	biological_process	apical protein localization
G	0045211	cellular_component	postsynaptic membrane
G	0048787	cellular_component	presynaptic active zone membrane
G	0055093	biological_process	response to hyperoxia
G	0061025	biological_process	membrane fusion
G	0070044	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a complex
G	0097060	cellular_component	synaptic membrane
G	0098793	cellular_component	presynapse
G	0098794	cellular_component	postsynapse
G	0098978	cellular_component	glutamatergic synapse
H	0000149	molecular_function	SNARE binding
H	0005483	molecular_function	soluble NSF attachment protein activity
H	0005515	molecular_function	protein binding
H	0005739	cellular_component	mitochondrion
H	0005886	cellular_component	plasma membrane
H	0006886	biological_process	intracellular protein transport
H	0007420	biological_process	brain development
H	0008021	cellular_component	synaptic vesicle
H	0010807	biological_process	regulation of synaptic vesicle priming
H	0015031	biological_process	protein transport
H	0016082	biological_process	synaptic vesicle priming
H	0016192	biological_process	vesicle-mediated transport
H	0019905	molecular_function	syntaxin binding
H	0030182	biological_process	neuron differentiation
H	0030425	cellular_component	dendrite
H	0031410	cellular_component	cytoplasmic vesicle
H	0031594	cellular_component	neuromuscular junction
H	0032781	biological_process	positive regulation of ATP-dependent activity
H	0032984	biological_process	protein-containing complex disassembly
H	0035249	biological_process	synaptic transmission, glutamatergic
H	0035494	biological_process	SNARE complex disassembly
H	0042599	cellular_component	lamellar body
H	0042734	cellular_component	presynaptic membrane
H	0043195	cellular_component	terminal bouton
H	0043204	cellular_component	perikaryon
H	0044877	molecular_function	protein-containing complex binding
H	0045176	biological_process	apical protein localization
H	0045211	cellular_component	postsynaptic membrane
H	0048787	cellular_component	presynaptic active zone membrane
H	0055093	biological_process	response to hyperoxia
H	0061025	biological_process	membrane fusion
H	0070044	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a complex
H	0097060	cellular_component	synaptic membrane
H	0098793	cellular_component	presynapse
H	0098794	cellular_component	postsynapse
H	0098978	cellular_component	glutamatergic synapse
J	0000149	molecular_function	SNARE binding
J	0000166	molecular_function	nucleotide binding
J	0001921	biological_process	positive regulation of receptor recycling
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0005795	cellular_component	Golgi stack
J	0005829	cellular_component	cytosol
J	0005886	cellular_component	plasma membrane
J	0006886	biological_process	intracellular protein transport
J	0006891	biological_process	intra-Golgi vesicle-mediated transport
J	0015031	biological_process	protein transport
J	0016787	molecular_function	hydrolase activity
J	0016887	molecular_function	ATP hydrolysis activity
J	0017075	molecular_function	syntaxin-1 binding
J	0019901	molecular_function	protein kinase binding
J	0019905	molecular_function	syntaxin binding
J	0030165	molecular_function	PDZ domain binding
J	0030496	cellular_component	midbody
J	0035255	molecular_function	ionotropic glutamate receptor binding
J	0035494	biological_process	SNARE complex disassembly
J	0042802	molecular_function	identical protein binding
J	0043001	biological_process	Golgi to plasma membrane protein transport
J	0044877	molecular_function	protein-containing complex binding
J	0045732	biological_process	positive regulation of protein catabolic process
J	0046872	molecular_function	metal ion binding
J	0140545	molecular_function	ATP-dependent protein disaggregase activity
K	0000149	molecular_function	SNARE binding
K	0000166	molecular_function	nucleotide binding
K	0001921	biological_process	positive regulation of receptor recycling
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005795	cellular_component	Golgi stack
K	0005829	cellular_component	cytosol
K	0005886	cellular_component	plasma membrane
K	0006886	biological_process	intracellular protein transport
K	0006891	biological_process	intra-Golgi vesicle-mediated transport
K	0015031	biological_process	protein transport
K	0016787	molecular_function	hydrolase activity
K	0016887	molecular_function	ATP hydrolysis activity
K	0017075	molecular_function	syntaxin-1 binding
K	0019901	molecular_function	protein kinase binding
K	0019905	molecular_function	syntaxin binding
K	0030165	molecular_function	PDZ domain binding
K	0030496	cellular_component	midbody
K	0035255	molecular_function	ionotropic glutamate receptor binding
K	0035494	biological_process	SNARE complex disassembly
K	0042802	molecular_function	identical protein binding
K	0043001	biological_process	Golgi to plasma membrane protein transport
K	0044877	molecular_function	protein-containing complex binding
K	0045732	biological_process	positive regulation of protein catabolic process
K	0046872	molecular_function	metal ion binding
K	0140545	molecular_function	ATP-dependent protein disaggregase activity

Functional Information from PROSITE/UniProt

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. IlVIgMTNrpdlIDeALl.R

Chain	Residue	Details
J	ILE367-ARG385

---

site_id	PS00914
Number of Residues	40
Details	SYNTAXIN Syntaxin / epimorphin family signature. RhseIikLEnsIrELhdMFmdMamlVesQGemIDrIEyn.V

Chain	Residue	Details
B	ARG198-VAL237

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	124
Details	Domain: {"description":"t-SNARE coiled-coil homology 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00202","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	124
Details	Domain: {"description":"t-SNARE coiled-coil homology","evidences":[{"source":"PROSITE-ProRule","id":"PRU00202","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Site: {"description":"(Microbial infection) Cleavage; by C.botulinum neurotoxin type C (BoNT/C)","evidences":[{"source":"PubMed","id":"7737992","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"UniProtKB","id":"Q16623","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"UniProtKB","id":"P54920","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9DB05","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P54920","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P46460","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues
Details	M-CSA 642

Chain

Residue

Details

---

site_id	MCSA2
Number of Residues
Details	M-CSA 642

Chain

Residue

Details

---