9PFF

Min22bin20S complex (NSF-alphaSNAP-2:2 syntaxin-1a H3:SNAP-25 SN1), non-hydrolyzing, class 27

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000149	molecular_function	SNARE binding
A	0000166	molecular_function	nucleotide binding
A	0001921	biological_process	positive regulation of receptor recycling
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005795	cellular_component	Golgi stack
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006886	biological_process	intracellular protein transport
A	0006891	biological_process	intra-Golgi vesicle-mediated transport
A	0015031	biological_process	protein transport
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0017075	molecular_function	syntaxin-1 binding
A	0019901	molecular_function	protein kinase binding
A	0019905	molecular_function	syntaxin binding
A	0030165	molecular_function	PDZ domain binding
A	0030496	cellular_component	midbody
A	0035255	molecular_function	ionotropic glutamate receptor binding
A	0035494	biological_process	SNARE complex disassembly
A	0042802	molecular_function	identical protein binding
A	0043001	biological_process	Golgi to plasma membrane protein transport
A	0044877	molecular_function	protein-containing complex binding
A	0045732	biological_process	positive regulation of protein catabolic process
A	0046872	molecular_function	metal ion binding
A	0140545	molecular_function	ATP-dependent protein disaggregase activity
B	0000149	molecular_function	SNARE binding
B	0000166	molecular_function	nucleotide binding
B	0001921	biological_process	positive regulation of receptor recycling
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005795	cellular_component	Golgi stack
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006886	biological_process	intracellular protein transport
B	0006891	biological_process	intra-Golgi vesicle-mediated transport
B	0015031	biological_process	protein transport
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0017075	molecular_function	syntaxin-1 binding
B	0019901	molecular_function	protein kinase binding
B	0019905	molecular_function	syntaxin binding
B	0030165	molecular_function	PDZ domain binding
B	0030496	cellular_component	midbody
B	0035255	molecular_function	ionotropic glutamate receptor binding
B	0035494	biological_process	SNARE complex disassembly
B	0042802	molecular_function	identical protein binding
B	0043001	biological_process	Golgi to plasma membrane protein transport
B	0044877	molecular_function	protein-containing complex binding
B	0045732	biological_process	positive regulation of protein catabolic process
B	0046872	molecular_function	metal ion binding
B	0140545	molecular_function	ATP-dependent protein disaggregase activity
C	0000149	molecular_function	SNARE binding
C	0000166	molecular_function	nucleotide binding
C	0001921	biological_process	positive regulation of receptor recycling
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005795	cellular_component	Golgi stack
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006886	biological_process	intracellular protein transport
C	0006891	biological_process	intra-Golgi vesicle-mediated transport
C	0015031	biological_process	protein transport
C	0016787	molecular_function	hydrolase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0017075	molecular_function	syntaxin-1 binding
C	0019901	molecular_function	protein kinase binding
C	0019905	molecular_function	syntaxin binding
C	0030165	molecular_function	PDZ domain binding
C	0030496	cellular_component	midbody
C	0035255	molecular_function	ionotropic glutamate receptor binding
C	0035494	biological_process	SNARE complex disassembly
C	0042802	molecular_function	identical protein binding
C	0043001	biological_process	Golgi to plasma membrane protein transport
C	0044877	molecular_function	protein-containing complex binding
C	0045732	biological_process	positive regulation of protein catabolic process
C	0046872	molecular_function	metal ion binding
C	0140545	molecular_function	ATP-dependent protein disaggregase activity
D	0000149	molecular_function	SNARE binding
D	0000166	molecular_function	nucleotide binding
D	0001921	biological_process	positive regulation of receptor recycling
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005795	cellular_component	Golgi stack
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006886	biological_process	intracellular protein transport
D	0006891	biological_process	intra-Golgi vesicle-mediated transport
D	0015031	biological_process	protein transport
D	0016787	molecular_function	hydrolase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0017075	molecular_function	syntaxin-1 binding
D	0019901	molecular_function	protein kinase binding
D	0019905	molecular_function	syntaxin binding
D	0030165	molecular_function	PDZ domain binding
D	0030496	cellular_component	midbody
D	0035255	molecular_function	ionotropic glutamate receptor binding
D	0035494	biological_process	SNARE complex disassembly
D	0042802	molecular_function	identical protein binding
D	0043001	biological_process	Golgi to plasma membrane protein transport
D	0044877	molecular_function	protein-containing complex binding
D	0045732	biological_process	positive regulation of protein catabolic process
D	0046872	molecular_function	metal ion binding
D	0140545	molecular_function	ATP-dependent protein disaggregase activity
E	0000149	molecular_function	SNARE binding
E	0000166	molecular_function	nucleotide binding
E	0001921	biological_process	positive regulation of receptor recycling
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005795	cellular_component	Golgi stack
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006886	biological_process	intracellular protein transport
E	0006891	biological_process	intra-Golgi vesicle-mediated transport
E	0015031	biological_process	protein transport
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0017075	molecular_function	syntaxin-1 binding
E	0019901	molecular_function	protein kinase binding
E	0019905	molecular_function	syntaxin binding
E	0030165	molecular_function	PDZ domain binding
E	0030496	cellular_component	midbody
E	0035255	molecular_function	ionotropic glutamate receptor binding
E	0035494	biological_process	SNARE complex disassembly
E	0042802	molecular_function	identical protein binding
E	0043001	biological_process	Golgi to plasma membrane protein transport
E	0044877	molecular_function	protein-containing complex binding
E	0045732	biological_process	positive regulation of protein catabolic process
E	0046872	molecular_function	metal ion binding
E	0140545	molecular_function	ATP-dependent protein disaggregase activity
F	0000149	molecular_function	SNARE binding
F	0000166	molecular_function	nucleotide binding
F	0001921	biological_process	positive regulation of receptor recycling
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005795	cellular_component	Golgi stack
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006886	biological_process	intracellular protein transport
F	0006891	biological_process	intra-Golgi vesicle-mediated transport
F	0015031	biological_process	protein transport
F	0016787	molecular_function	hydrolase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0017075	molecular_function	syntaxin-1 binding
F	0019901	molecular_function	protein kinase binding
F	0019905	molecular_function	syntaxin binding
F	0030165	molecular_function	PDZ domain binding
F	0030496	cellular_component	midbody
F	0035255	molecular_function	ionotropic glutamate receptor binding
F	0035494	biological_process	SNARE complex disassembly
F	0042802	molecular_function	identical protein binding
F	0043001	biological_process	Golgi to plasma membrane protein transport
F	0044877	molecular_function	protein-containing complex binding
F	0045732	biological_process	positive regulation of protein catabolic process
F	0046872	molecular_function	metal ion binding
F	0140545	molecular_function	ATP-dependent protein disaggregase activity
L	0000149	molecular_function	SNARE binding
L	0005483	molecular_function	soluble NSF attachment protein activity
L	0005515	molecular_function	protein binding
L	0005739	cellular_component	mitochondrion
L	0005886	cellular_component	plasma membrane
L	0006886	biological_process	intracellular protein transport
L	0007420	biological_process	brain development
L	0008021	cellular_component	synaptic vesicle
L	0010807	biological_process	regulation of synaptic vesicle priming
L	0015031	biological_process	protein transport
L	0016082	biological_process	synaptic vesicle priming
L	0016192	biological_process	vesicle-mediated transport
L	0019905	molecular_function	syntaxin binding
L	0030182	biological_process	neuron differentiation
L	0030425	cellular_component	dendrite
L	0031410	cellular_component	cytoplasmic vesicle
L	0031594	cellular_component	neuromuscular junction
L	0032781	biological_process	positive regulation of ATP-dependent activity
L	0032984	biological_process	protein-containing complex disassembly
L	0035249	biological_process	synaptic transmission, glutamatergic
L	0035494	biological_process	SNARE complex disassembly
L	0042599	cellular_component	lamellar body
L	0042734	cellular_component	presynaptic membrane
L	0043195	cellular_component	terminal bouton
L	0043204	cellular_component	perikaryon
L	0044877	molecular_function	protein-containing complex binding
L	0045176	biological_process	apical protein localization
L	0045211	cellular_component	postsynaptic membrane
L	0048787	cellular_component	presynaptic active zone membrane
L	0055093	biological_process	response to hyperoxia
L	0061025	biological_process	membrane fusion
L	0070044	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a complex
L	0097060	cellular_component	synaptic membrane
L	0098793	cellular_component	presynapse
L	0098794	cellular_component	postsynapse
L	0098978	cellular_component	glutamatergic synapse
M	0000149	molecular_function	SNARE binding
M	0005483	molecular_function	soluble NSF attachment protein activity
M	0005515	molecular_function	protein binding
M	0005739	cellular_component	mitochondrion
M	0005886	cellular_component	plasma membrane
M	0006886	biological_process	intracellular protein transport
M	0007420	biological_process	brain development
M	0008021	cellular_component	synaptic vesicle
M	0010807	biological_process	regulation of synaptic vesicle priming
M	0015031	biological_process	protein transport
M	0016082	biological_process	synaptic vesicle priming
M	0016192	biological_process	vesicle-mediated transport
M	0019905	molecular_function	syntaxin binding
M	0030182	biological_process	neuron differentiation
M	0030425	cellular_component	dendrite
M	0031410	cellular_component	cytoplasmic vesicle
M	0031594	cellular_component	neuromuscular junction
M	0032781	biological_process	positive regulation of ATP-dependent activity
M	0032984	biological_process	protein-containing complex disassembly
M	0035249	biological_process	synaptic transmission, glutamatergic
M	0035494	biological_process	SNARE complex disassembly
M	0042599	cellular_component	lamellar body
M	0042734	cellular_component	presynaptic membrane
M	0043195	cellular_component	terminal bouton
M	0043204	cellular_component	perikaryon
M	0044877	molecular_function	protein-containing complex binding
M	0045176	biological_process	apical protein localization
M	0045211	cellular_component	postsynaptic membrane
M	0048787	cellular_component	presynaptic active zone membrane
M	0055093	biological_process	response to hyperoxia
M	0061025	biological_process	membrane fusion
M	0070044	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a complex
M	0097060	cellular_component	synaptic membrane
M	0098793	cellular_component	presynapse
M	0098794	cellular_component	postsynapse
M	0098978	cellular_component	glutamatergic synapse
N	0000149	molecular_function	SNARE binding
N	0005483	molecular_function	soluble NSF attachment protein activity
N	0005515	molecular_function	protein binding
N	0005739	cellular_component	mitochondrion
N	0005886	cellular_component	plasma membrane
N	0006886	biological_process	intracellular protein transport
N	0007420	biological_process	brain development
N	0008021	cellular_component	synaptic vesicle
N	0010807	biological_process	regulation of synaptic vesicle priming
N	0015031	biological_process	protein transport
N	0016082	biological_process	synaptic vesicle priming
N	0016192	biological_process	vesicle-mediated transport
N	0019905	molecular_function	syntaxin binding
N	0030182	biological_process	neuron differentiation
N	0030425	cellular_component	dendrite
N	0031410	cellular_component	cytoplasmic vesicle
N	0031594	cellular_component	neuromuscular junction
N	0032781	biological_process	positive regulation of ATP-dependent activity
N	0032984	biological_process	protein-containing complex disassembly
N	0035249	biological_process	synaptic transmission, glutamatergic
N	0035494	biological_process	SNARE complex disassembly
N	0042599	cellular_component	lamellar body
N	0042734	cellular_component	presynaptic membrane
N	0043195	cellular_component	terminal bouton
N	0043204	cellular_component	perikaryon
N	0044877	molecular_function	protein-containing complex binding
N	0045176	biological_process	apical protein localization
N	0045211	cellular_component	postsynaptic membrane
N	0048787	cellular_component	presynaptic active zone membrane
N	0055093	biological_process	response to hyperoxia
N	0061025	biological_process	membrane fusion
N	0070044	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a complex
N	0097060	cellular_component	synaptic membrane
N	0098793	cellular_component	presynapse
N	0098794	cellular_component	postsynapse
N	0098978	cellular_component	glutamatergic synapse
O	0000149	molecular_function	SNARE binding
O	0005483	molecular_function	soluble NSF attachment protein activity
O	0005515	molecular_function	protein binding
O	0005739	cellular_component	mitochondrion
O	0005886	cellular_component	plasma membrane
O	0006886	biological_process	intracellular protein transport
O	0007420	biological_process	brain development
O	0008021	cellular_component	synaptic vesicle
O	0010807	biological_process	regulation of synaptic vesicle priming
O	0015031	biological_process	protein transport
O	0016082	biological_process	synaptic vesicle priming
O	0016192	biological_process	vesicle-mediated transport
O	0019905	molecular_function	syntaxin binding
O	0030182	biological_process	neuron differentiation
O	0030425	cellular_component	dendrite
O	0031410	cellular_component	cytoplasmic vesicle
O	0031594	cellular_component	neuromuscular junction
O	0032781	biological_process	positive regulation of ATP-dependent activity
O	0032984	biological_process	protein-containing complex disassembly
O	0035249	biological_process	synaptic transmission, glutamatergic
O	0035494	biological_process	SNARE complex disassembly
O	0042599	cellular_component	lamellar body
O	0042734	cellular_component	presynaptic membrane
O	0043195	cellular_component	terminal bouton
O	0043204	cellular_component	perikaryon
O	0044877	molecular_function	protein-containing complex binding
O	0045176	biological_process	apical protein localization
O	0045211	cellular_component	postsynaptic membrane
O	0048787	cellular_component	presynaptic active zone membrane
O	0055093	biological_process	response to hyperoxia
O	0061025	biological_process	membrane fusion
O	0070044	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a complex
O	0097060	cellular_component	synaptic membrane
O	0098793	cellular_component	presynapse
O	0098794	cellular_component	postsynapse
O	0098978	cellular_component	glutamatergic synapse

Functional Information from PROSITE/UniProt

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. IlVIgMTNrpdlIDeALl.R

Chain	Residue	Details
A	ILE367-ARG385

---

site_id	PS00914
Number of Residues	40
Details	SYNTAXIN Syntaxin / epimorphin family signature. RhseIikLEnsIrELhdMFmdMamlVesQGemIDrIEyn.V

Chain	Residue	Details
H	ARG198-VAL237

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	62
Details	Domain: {"description":"t-SNARE coiled-coil homology 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00202","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	124
Details	Domain: {"description":"t-SNARE coiled-coil homology","evidences":[{"source":"PROSITE-ProRule","id":"PRU00202","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Site: {"description":"(Microbial infection) Cleavage; by C.botulinum neurotoxin type C (BoNT/C)","evidences":[{"source":"PubMed","id":"7737992","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"UniProtKB","id":"Q16623","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"UniProtKB","id":"P54920","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9DB05","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P54920","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	72
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9731775","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9727495","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9731775","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	6
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P46460","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	6
Details	Modified residue: {"description":"Phosphoserine; by CDK16","evidences":[{"source":"UniProtKB","id":"P46460","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P46460","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P46459","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	6
Details	M-CSA 642

Chain

Residue

Details

---

site_id	MCSA2
Number of Residues	6
Details	M-CSA 642

Chain

Residue

Details

---

site_id	MCSA3
Number of Residues	6
Details	M-CSA 642

Chain

Residue

Details

---

site_id	MCSA4
Number of Residues	6
Details	M-CSA 642

Chain

Residue

Details

---

site_id	MCSA5
Number of Residues	6
Details	M-CSA 642

Chain

Residue

Details

---

site_id	MCSA6
Number of Residues	6
Details	M-CSA 642

Chain

Residue

Details

---