9OTQ

Human glutamine synthetase filament apo

Functional Information from PROSITE/UniProt

site_id	PS00180
Number of Residues	18
Details	GLNA_1 Glutamine synthetase signature 1. FDGSStlqsegs.NSDmyL

Chain	Residue	Details
L	PHE62-LEU79

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site_id	PS00181
Number of Residues	17
Details	GLNA_ATP Glutamine synthetase putative ATP-binding region signature. KPIpgnw.NGAGcHtnfS

Chain	Residue	Details
L	LYS241-SER257

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1640
Details	Domain: {"description":"GS beta-grasp","evidences":[{"source":"PROSITE-ProRule","id":"PRU01330","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	460
Details	Region: {"description":"Required for glutamine-induced ubiquitination by CRL4(CRBN) and proteasomal degradation","evidences":[{"source":"PubMed","id":"26990986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38579670","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	120
Details	Binding site: {"evidences":[{"source":"PDB","id":"2QC8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	200
Details	Binding site: {"evidences":[{"source":"PDB","id":"2OJW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QC8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P9WN39","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	20
Details	Modified residue: {"description":"N-acetylthreonine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	40
Details	Modified residue: {"description":"N6-acetyllysine; by EP300","evidences":[{"source":"PubMed","id":"26990986","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI8
Number of Residues	20
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P15105","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI9
Number of Residues	20
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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