9OQ5
Structure of the human sweet receptor bound to advantame in the intermediate state, extracellular domain
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001582 | biological_process | detection of chemical stimulus involved in sensory perception of sweet taste |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0008527 | molecular_function | taste receptor activity |
| A | 0016020 | cellular_component | membrane |
| A | 0032467 | biological_process | positive regulation of cytokinesis |
| A | 0033041 | molecular_function | sweet taste receptor activity |
| A | 0038037 | cellular_component | G protein-coupled receptor dimeric complex |
| A | 0043235 | cellular_component | signaling receptor complex |
| A | 0050909 | biological_process | sensory perception of taste |
| A | 0050916 | biological_process | sensory perception of sweet taste |
| A | 1903767 | cellular_component | sweet taste receptor complex |
| B | 0001582 | biological_process | detection of chemical stimulus involved in sensory perception of sweet taste |
| B | 0004930 | molecular_function | G protein-coupled receptor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| B | 0008527 | molecular_function | taste receptor activity |
| B | 0016020 | cellular_component | membrane |
| B | 0033041 | molecular_function | sweet taste receptor activity |
| B | 0038037 | cellular_component | G protein-coupled receptor dimeric complex |
| B | 0050909 | biological_process | sensory perception of taste |
| B | 0050916 | biological_process | sensory perception of sweet taste |
| B | 0050917 | biological_process | sensory perception of umami taste |
| B | 1903767 | cellular_component | sweet taste receptor complex |
Functional Information from PROSITE/UniProt
| site_id | PS00980 |
| Number of Residues | 26 |
| Details | G_PROTEIN_RECEP_F3_2 G-protein coupled receptors family 3 signature 2. CCFeCidClpgtFlnhteDeyECqaC |
| Chain | Residue | Details |
| A | CYS513-CYS538 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 15 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"40339580","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9NOR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NOS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NOT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NOU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NOV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NOW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"40339580","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9NOR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NOS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NOT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Region: {"description":"Required for brazzein responsiveness","evidences":[{"source":"PubMed","id":"15299024","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
