9OOO
Human delta 2 receptor with R710W Cerebellar Ataxia mutation in the apo closed state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0038023 | molecular_function | signaling receptor activity |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
| B | 0038023 | molecular_function | signaling receptor activity |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| C | 0016020 | cellular_component | membrane |
| C | 0038023 | molecular_function | signaling receptor activity |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| D | 0016020 | cellular_component | membrane |
| D | 0038023 | molecular_function | signaling receptor activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 80 |
| Details | Transmembrane: {"description":"Helical; Name=M1","evidences":[{"source":"PubMed","id":"40957579","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9NWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OOO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 92 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"40957579","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9NWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OOO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 44 |
| Details | Intramembrane: {"description":"Helical; Name=M2","evidences":[{"source":"PubMed","id":"40957579","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9NWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OOO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 112 |
| Details | Transmembrane: {"description":"Helical; Name=M3","evidences":[{"source":"PubMed","id":"40957579","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9NWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OOO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 704 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"40957579","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9NWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OOO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 80 |
| Details | Transmembrane: {"description":"Helical; Name=M4","evidences":[{"source":"PubMed","id":"40957579","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9NWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9NWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9OOO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 44 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"40957579","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9NWP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9ULK0","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | Site: {"description":"Essential for dimerization","evidences":[{"source":"PubMed","id":"27418511","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 16 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
