9ON4

Crystal structure of Zn2+ bound Calprotectin variant I73K

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002523	biological_process	leukocyte migration involved in inflammatory response
A	0002544	biological_process	chronic inflammatory response
A	0005509	molecular_function	calcium ion binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0005886	cellular_component	plasma membrane
A	0006914	biological_process	autophagy
A	0006954	biological_process	inflammatory response
A	0008017	molecular_function	microtubule binding
A	0008270	molecular_function	zinc ion binding
A	0010043	biological_process	response to zinc ion
A	0018119	biological_process	peptidyl-cysteine S-nitrosylation
A	0030307	biological_process	positive regulation of cell growth
A	0030593	biological_process	neutrophil chemotaxis
A	0031012	cellular_component	extracellular matrix
A	0032496	biological_process	response to lipopolysaccharide
A	0034121	biological_process	regulation of toll-like receptor signaling pathway
A	0034774	cellular_component	secretory granule lumen
A	0035425	biological_process	autocrine signaling
A	0035662	molecular_function	Toll-like receptor 4 binding
A	0042742	biological_process	defense response to bacterium
A	0043542	biological_process	endothelial cell migration
A	0045111	cellular_component	intermediate filament cytoskeleton
A	0045471	biological_process	response to ethanol
A	0048306	molecular_function	calcium-dependent protein binding
A	0050544	molecular_function	arachidonate binding
A	0050729	biological_process	positive regulation of inflammatory response
A	0050786	molecular_function	RAGE receptor binding
A	0050832	biological_process	defense response to fungus
A	0051493	biological_process	regulation of cytoskeleton organization
A	0070062	cellular_component	extracellular exosome
A	0070488	biological_process	neutrophil aggregation
A	1990660	cellular_component	calprotectin complex
A	1990661	cellular_component	S100A8 complex
A	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
B	0002523	biological_process	leukocyte migration involved in inflammatory response
B	0002544	biological_process	chronic inflammatory response
B	0005509	molecular_function	calcium ion binding
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0005886	cellular_component	plasma membrane
B	0006914	biological_process	autophagy
B	0006954	biological_process	inflammatory response
B	0007267	biological_process	cell-cell signaling
B	0008017	molecular_function	microtubule binding
B	0008270	molecular_function	zinc ion binding
B	0010976	biological_process	positive regulation of neuron projection development
B	0014002	biological_process	astrocyte development
B	0030307	biological_process	positive regulation of cell growth
B	0030593	biological_process	neutrophil chemotaxis
B	0031012	cellular_component	extracellular matrix
B	0034121	biological_process	regulation of toll-like receptor signaling pathway
B	0034774	cellular_component	secretory granule lumen
B	0035425	biological_process	autocrine signaling
B	0035606	biological_process	peptidyl-cysteine S-trans-nitrosylation
B	0035662	molecular_function	Toll-like receptor 4 binding
B	0042742	biological_process	defense response to bacterium
B	0043542	biological_process	endothelial cell migration
B	0045111	cellular_component	intermediate filament cytoskeleton
B	0048306	molecular_function	calcium-dependent protein binding
B	0050544	molecular_function	arachidonate binding
B	0050729	biological_process	positive regulation of inflammatory response
B	0050786	molecular_function	RAGE receptor binding
B	0050832	biological_process	defense response to fungus
B	0051493	biological_process	regulation of cytoskeleton organization
B	0060264	biological_process	regulation of respiratory burst involved in inflammatory response
B	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
B	0070062	cellular_component	extracellular exosome
B	0070488	biological_process	neutrophil aggregation
B	1990660	cellular_component	calprotectin complex
B	1990662	cellular_component	S100A9 complex
B	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
C	0002523	biological_process	leukocyte migration involved in inflammatory response
C	0002544	biological_process	chronic inflammatory response
C	0005509	molecular_function	calcium ion binding
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005856	cellular_component	cytoskeleton
C	0005886	cellular_component	plasma membrane
C	0006914	biological_process	autophagy
C	0006954	biological_process	inflammatory response
C	0008017	molecular_function	microtubule binding
C	0008270	molecular_function	zinc ion binding
C	0010043	biological_process	response to zinc ion
C	0018119	biological_process	peptidyl-cysteine S-nitrosylation
C	0030307	biological_process	positive regulation of cell growth
C	0030593	biological_process	neutrophil chemotaxis
C	0031012	cellular_component	extracellular matrix
C	0032496	biological_process	response to lipopolysaccharide
C	0034121	biological_process	regulation of toll-like receptor signaling pathway
C	0034774	cellular_component	secretory granule lumen
C	0035425	biological_process	autocrine signaling
C	0035662	molecular_function	Toll-like receptor 4 binding
C	0042742	biological_process	defense response to bacterium
C	0043542	biological_process	endothelial cell migration
C	0045111	cellular_component	intermediate filament cytoskeleton
C	0045471	biological_process	response to ethanol
C	0048306	molecular_function	calcium-dependent protein binding
C	0050544	molecular_function	arachidonate binding
C	0050729	biological_process	positive regulation of inflammatory response
C	0050786	molecular_function	RAGE receptor binding
C	0050832	biological_process	defense response to fungus
C	0051493	biological_process	regulation of cytoskeleton organization
C	0070062	cellular_component	extracellular exosome
C	0070488	biological_process	neutrophil aggregation
C	1990660	cellular_component	calprotectin complex
C	1990661	cellular_component	S100A8 complex
C	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
D	0002523	biological_process	leukocyte migration involved in inflammatory response
D	0002544	biological_process	chronic inflammatory response
D	0005509	molecular_function	calcium ion binding
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005856	cellular_component	cytoskeleton
D	0005886	cellular_component	plasma membrane
D	0006914	biological_process	autophagy
D	0006954	biological_process	inflammatory response
D	0007267	biological_process	cell-cell signaling
D	0008017	molecular_function	microtubule binding
D	0008270	molecular_function	zinc ion binding
D	0010976	biological_process	positive regulation of neuron projection development
D	0014002	biological_process	astrocyte development
D	0030307	biological_process	positive regulation of cell growth
D	0030593	biological_process	neutrophil chemotaxis
D	0031012	cellular_component	extracellular matrix
D	0034121	biological_process	regulation of toll-like receptor signaling pathway
D	0034774	cellular_component	secretory granule lumen
D	0035425	biological_process	autocrine signaling
D	0035606	biological_process	peptidyl-cysteine S-trans-nitrosylation
D	0035662	molecular_function	Toll-like receptor 4 binding
D	0042742	biological_process	defense response to bacterium
D	0043542	biological_process	endothelial cell migration
D	0045111	cellular_component	intermediate filament cytoskeleton
D	0048306	molecular_function	calcium-dependent protein binding
D	0050544	molecular_function	arachidonate binding
D	0050729	biological_process	positive regulation of inflammatory response
D	0050786	molecular_function	RAGE receptor binding
D	0050832	biological_process	defense response to fungus
D	0051493	biological_process	regulation of cytoskeleton organization
D	0060264	biological_process	regulation of respiratory burst involved in inflammatory response
D	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
D	0070062	cellular_component	extracellular exosome
D	0070488	biological_process	neutrophil aggregation
D	1990660	cellular_component	calprotectin complex
D	1990662	cellular_component	S100A9 complex
D	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
E	0002523	biological_process	leukocyte migration involved in inflammatory response
E	0002544	biological_process	chronic inflammatory response
E	0005509	molecular_function	calcium ion binding
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005856	cellular_component	cytoskeleton
E	0005886	cellular_component	plasma membrane
E	0006914	biological_process	autophagy
E	0006954	biological_process	inflammatory response
E	0008017	molecular_function	microtubule binding
E	0008270	molecular_function	zinc ion binding
E	0010043	biological_process	response to zinc ion
E	0018119	biological_process	peptidyl-cysteine S-nitrosylation
E	0030307	biological_process	positive regulation of cell growth
E	0030593	biological_process	neutrophil chemotaxis
E	0031012	cellular_component	extracellular matrix
E	0032496	biological_process	response to lipopolysaccharide
E	0034121	biological_process	regulation of toll-like receptor signaling pathway
E	0034774	cellular_component	secretory granule lumen
E	0035425	biological_process	autocrine signaling
E	0035662	molecular_function	Toll-like receptor 4 binding
E	0042742	biological_process	defense response to bacterium
E	0043542	biological_process	endothelial cell migration
E	0045111	cellular_component	intermediate filament cytoskeleton
E	0045471	biological_process	response to ethanol
E	0048306	molecular_function	calcium-dependent protein binding
E	0050544	molecular_function	arachidonate binding
E	0050729	biological_process	positive regulation of inflammatory response
E	0050786	molecular_function	RAGE receptor binding
E	0050832	biological_process	defense response to fungus
E	0051493	biological_process	regulation of cytoskeleton organization
E	0070062	cellular_component	extracellular exosome
E	0070488	biological_process	neutrophil aggregation
E	1990660	cellular_component	calprotectin complex
E	1990661	cellular_component	S100A8 complex
E	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
F	0002523	biological_process	leukocyte migration involved in inflammatory response
F	0002544	biological_process	chronic inflammatory response
F	0005509	molecular_function	calcium ion binding
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005856	cellular_component	cytoskeleton
F	0005886	cellular_component	plasma membrane
F	0006914	biological_process	autophagy
F	0006954	biological_process	inflammatory response
F	0007267	biological_process	cell-cell signaling
F	0008017	molecular_function	microtubule binding
F	0008270	molecular_function	zinc ion binding
F	0010976	biological_process	positive regulation of neuron projection development
F	0014002	biological_process	astrocyte development
F	0030307	biological_process	positive regulation of cell growth
F	0030593	biological_process	neutrophil chemotaxis
F	0031012	cellular_component	extracellular matrix
F	0034121	biological_process	regulation of toll-like receptor signaling pathway
F	0034774	cellular_component	secretory granule lumen
F	0035425	biological_process	autocrine signaling
F	0035606	biological_process	peptidyl-cysteine S-trans-nitrosylation
F	0035662	molecular_function	Toll-like receptor 4 binding
F	0042742	biological_process	defense response to bacterium
F	0043542	biological_process	endothelial cell migration
F	0045111	cellular_component	intermediate filament cytoskeleton
F	0048306	molecular_function	calcium-dependent protein binding
F	0050544	molecular_function	arachidonate binding
F	0050729	biological_process	positive regulation of inflammatory response
F	0050786	molecular_function	RAGE receptor binding
F	0050832	biological_process	defense response to fungus
F	0051493	biological_process	regulation of cytoskeleton organization
F	0060264	biological_process	regulation of respiratory burst involved in inflammatory response
F	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
F	0070062	cellular_component	extracellular exosome
F	0070488	biological_process	neutrophil aggregation
F	1990660	cellular_component	calprotectin complex
F	1990662	cellular_component	S100A9 complex
F	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
G	0002523	biological_process	leukocyte migration involved in inflammatory response
G	0002544	biological_process	chronic inflammatory response
G	0005509	molecular_function	calcium ion binding
G	0005515	molecular_function	protein binding
G	0005576	cellular_component	extracellular region
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005856	cellular_component	cytoskeleton
G	0005886	cellular_component	plasma membrane
G	0006914	biological_process	autophagy
G	0006954	biological_process	inflammatory response
G	0008017	molecular_function	microtubule binding
G	0008270	molecular_function	zinc ion binding
G	0010043	biological_process	response to zinc ion
G	0018119	biological_process	peptidyl-cysteine S-nitrosylation
G	0030307	biological_process	positive regulation of cell growth
G	0030593	biological_process	neutrophil chemotaxis
G	0031012	cellular_component	extracellular matrix
G	0032496	biological_process	response to lipopolysaccharide
G	0034121	biological_process	regulation of toll-like receptor signaling pathway
G	0034774	cellular_component	secretory granule lumen
G	0035425	biological_process	autocrine signaling
G	0035662	molecular_function	Toll-like receptor 4 binding
G	0042742	biological_process	defense response to bacterium
G	0043542	biological_process	endothelial cell migration
G	0045111	cellular_component	intermediate filament cytoskeleton
G	0045471	biological_process	response to ethanol
G	0048306	molecular_function	calcium-dependent protein binding
G	0050544	molecular_function	arachidonate binding
G	0050729	biological_process	positive regulation of inflammatory response
G	0050786	molecular_function	RAGE receptor binding
G	0050832	biological_process	defense response to fungus
G	0051493	biological_process	regulation of cytoskeleton organization
G	0070062	cellular_component	extracellular exosome
G	0070488	biological_process	neutrophil aggregation
G	1990660	cellular_component	calprotectin complex
G	1990661	cellular_component	S100A8 complex
G	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
H	0002523	biological_process	leukocyte migration involved in inflammatory response
H	0002544	biological_process	chronic inflammatory response
H	0005509	molecular_function	calcium ion binding
H	0005515	molecular_function	protein binding
H	0005576	cellular_component	extracellular region
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005856	cellular_component	cytoskeleton
H	0005886	cellular_component	plasma membrane
H	0006914	biological_process	autophagy
H	0006954	biological_process	inflammatory response
H	0007267	biological_process	cell-cell signaling
H	0008017	molecular_function	microtubule binding
H	0008270	molecular_function	zinc ion binding
H	0010976	biological_process	positive regulation of neuron projection development
H	0014002	biological_process	astrocyte development
H	0030307	biological_process	positive regulation of cell growth
H	0030593	biological_process	neutrophil chemotaxis
H	0031012	cellular_component	extracellular matrix
H	0034121	biological_process	regulation of toll-like receptor signaling pathway
H	0034774	cellular_component	secretory granule lumen
H	0035425	biological_process	autocrine signaling
H	0035606	biological_process	peptidyl-cysteine S-trans-nitrosylation
H	0035662	molecular_function	Toll-like receptor 4 binding
H	0042742	biological_process	defense response to bacterium
H	0043542	biological_process	endothelial cell migration
H	0045111	cellular_component	intermediate filament cytoskeleton
H	0048306	molecular_function	calcium-dependent protein binding
H	0050544	molecular_function	arachidonate binding
H	0050729	biological_process	positive regulation of inflammatory response
H	0050786	molecular_function	RAGE receptor binding
H	0050832	biological_process	defense response to fungus
H	0051493	biological_process	regulation of cytoskeleton organization
H	0060264	biological_process	regulation of respiratory burst involved in inflammatory response
H	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
H	0070062	cellular_component	extracellular exosome
H	0070488	biological_process	neutrophil aggregation
H	1990660	cellular_component	calprotectin complex
H	1990662	cellular_component	S100A9 complex
H	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
IA	0002523	biological_process	leukocyte migration involved in inflammatory response
IA	0002544	biological_process	chronic inflammatory response
IA	0005509	molecular_function	calcium ion binding
IA	0005515	molecular_function	protein binding
IA	0005576	cellular_component	extracellular region
IA	0005634	cellular_component	nucleus
IA	0005737	cellular_component	cytoplasm
IA	0005829	cellular_component	cytosol
IA	0005856	cellular_component	cytoskeleton
IA	0005886	cellular_component	plasma membrane
IA	0006914	biological_process	autophagy
IA	0006954	biological_process	inflammatory response
IA	0008017	molecular_function	microtubule binding
IA	0008270	molecular_function	zinc ion binding
IA	0010043	biological_process	response to zinc ion
IA	0018119	biological_process	peptidyl-cysteine S-nitrosylation
IA	0030307	biological_process	positive regulation of cell growth
IA	0030593	biological_process	neutrophil chemotaxis
IA	0031012	cellular_component	extracellular matrix
IA	0032496	biological_process	response to lipopolysaccharide
IA	0034121	biological_process	regulation of toll-like receptor signaling pathway
IA	0034774	cellular_component	secretory granule lumen
IA	0035425	biological_process	autocrine signaling
IA	0035662	molecular_function	Toll-like receptor 4 binding
IA	0042742	biological_process	defense response to bacterium
IA	0043542	biological_process	endothelial cell migration
IA	0045111	cellular_component	intermediate filament cytoskeleton
IA	0045471	biological_process	response to ethanol
IA	0048306	molecular_function	calcium-dependent protein binding
IA	0050544	molecular_function	arachidonate binding
IA	0050729	biological_process	positive regulation of inflammatory response
IA	0050786	molecular_function	RAGE receptor binding
IA	0050832	biological_process	defense response to fungus
IA	0051493	biological_process	regulation of cytoskeleton organization
IA	0070062	cellular_component	extracellular exosome
IA	0070488	biological_process	neutrophil aggregation
IA	1990660	cellular_component	calprotectin complex
IA	1990661	cellular_component	S100A8 complex
IA	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
JA	0002523	biological_process	leukocyte migration involved in inflammatory response
JA	0002544	biological_process	chronic inflammatory response
JA	0005509	molecular_function	calcium ion binding
JA	0005515	molecular_function	protein binding
JA	0005576	cellular_component	extracellular region
JA	0005634	cellular_component	nucleus
JA	0005737	cellular_component	cytoplasm
JA	0005829	cellular_component	cytosol
JA	0005856	cellular_component	cytoskeleton
JA	0005886	cellular_component	plasma membrane
JA	0006914	biological_process	autophagy
JA	0006954	biological_process	inflammatory response
JA	0007267	biological_process	cell-cell signaling
JA	0008017	molecular_function	microtubule binding
JA	0008270	molecular_function	zinc ion binding
JA	0010976	biological_process	positive regulation of neuron projection development
JA	0014002	biological_process	astrocyte development
JA	0030307	biological_process	positive regulation of cell growth
JA	0030593	biological_process	neutrophil chemotaxis
JA	0031012	cellular_component	extracellular matrix
JA	0034121	biological_process	regulation of toll-like receptor signaling pathway
JA	0034774	cellular_component	secretory granule lumen
JA	0035425	biological_process	autocrine signaling
JA	0035606	biological_process	peptidyl-cysteine S-trans-nitrosylation
JA	0035662	molecular_function	Toll-like receptor 4 binding
JA	0042742	biological_process	defense response to bacterium
JA	0043542	biological_process	endothelial cell migration
JA	0045111	cellular_component	intermediate filament cytoskeleton
JA	0048306	molecular_function	calcium-dependent protein binding
JA	0050544	molecular_function	arachidonate binding
JA	0050729	biological_process	positive regulation of inflammatory response
JA	0050786	molecular_function	RAGE receptor binding
JA	0050832	biological_process	defense response to fungus
JA	0051493	biological_process	regulation of cytoskeleton organization
JA	0060264	biological_process	regulation of respiratory burst involved in inflammatory response
JA	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
JA	0070062	cellular_component	extracellular exosome
JA	0070488	biological_process	neutrophil aggregation
JA	1990660	cellular_component	calprotectin complex
JA	1990662	cellular_component	S100A9 complex
JA	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
KA	0002523	biological_process	leukocyte migration involved in inflammatory response
KA	0002544	biological_process	chronic inflammatory response
KA	0005509	molecular_function	calcium ion binding
KA	0005515	molecular_function	protein binding
KA	0005576	cellular_component	extracellular region
KA	0005634	cellular_component	nucleus
KA	0005737	cellular_component	cytoplasm
KA	0005829	cellular_component	cytosol
KA	0005856	cellular_component	cytoskeleton
KA	0005886	cellular_component	plasma membrane
KA	0006914	biological_process	autophagy
KA	0006954	biological_process	inflammatory response
KA	0008017	molecular_function	microtubule binding
KA	0008270	molecular_function	zinc ion binding
KA	0010043	biological_process	response to zinc ion
KA	0018119	biological_process	peptidyl-cysteine S-nitrosylation
KA	0030307	biological_process	positive regulation of cell growth
KA	0030593	biological_process	neutrophil chemotaxis
KA	0031012	cellular_component	extracellular matrix
KA	0032496	biological_process	response to lipopolysaccharide
KA	0034121	biological_process	regulation of toll-like receptor signaling pathway
KA	0034774	cellular_component	secretory granule lumen
KA	0035425	biological_process	autocrine signaling
KA	0035662	molecular_function	Toll-like receptor 4 binding
KA	0042742	biological_process	defense response to bacterium
KA	0043542	biological_process	endothelial cell migration
KA	0045111	cellular_component	intermediate filament cytoskeleton
KA	0045471	biological_process	response to ethanol
KA	0048306	molecular_function	calcium-dependent protein binding
KA	0050544	molecular_function	arachidonate binding
KA	0050729	biological_process	positive regulation of inflammatory response
KA	0050786	molecular_function	RAGE receptor binding
KA	0050832	biological_process	defense response to fungus
KA	0051493	biological_process	regulation of cytoskeleton organization
KA	0070062	cellular_component	extracellular exosome
KA	0070488	biological_process	neutrophil aggregation
KA	1990660	cellular_component	calprotectin complex
KA	1990661	cellular_component	S100A8 complex
KA	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
LA	0002523	biological_process	leukocyte migration involved in inflammatory response
LA	0002544	biological_process	chronic inflammatory response
LA	0005509	molecular_function	calcium ion binding
LA	0005515	molecular_function	protein binding
LA	0005576	cellular_component	extracellular region
LA	0005634	cellular_component	nucleus
LA	0005737	cellular_component	cytoplasm
LA	0005829	cellular_component	cytosol
LA	0005856	cellular_component	cytoskeleton
LA	0005886	cellular_component	plasma membrane
LA	0006914	biological_process	autophagy
LA	0006954	biological_process	inflammatory response
LA	0007267	biological_process	cell-cell signaling
LA	0008017	molecular_function	microtubule binding
LA	0008270	molecular_function	zinc ion binding
LA	0010976	biological_process	positive regulation of neuron projection development
LA	0014002	biological_process	astrocyte development
LA	0030307	biological_process	positive regulation of cell growth
LA	0030593	biological_process	neutrophil chemotaxis
LA	0031012	cellular_component	extracellular matrix
LA	0034121	biological_process	regulation of toll-like receptor signaling pathway
LA	0034774	cellular_component	secretory granule lumen
LA	0035425	biological_process	autocrine signaling
LA	0035606	biological_process	peptidyl-cysteine S-trans-nitrosylation
LA	0035662	molecular_function	Toll-like receptor 4 binding
LA	0042742	biological_process	defense response to bacterium
LA	0043542	biological_process	endothelial cell migration
LA	0045111	cellular_component	intermediate filament cytoskeleton
LA	0048306	molecular_function	calcium-dependent protein binding
LA	0050544	molecular_function	arachidonate binding
LA	0050729	biological_process	positive regulation of inflammatory response
LA	0050786	molecular_function	RAGE receptor binding
LA	0050832	biological_process	defense response to fungus
LA	0051493	biological_process	regulation of cytoskeleton organization
LA	0060264	biological_process	regulation of respiratory burst involved in inflammatory response
LA	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
LA	0070062	cellular_component	extracellular exosome
LA	0070488	biological_process	neutrophil aggregation
LA	1990660	cellular_component	calprotectin complex
LA	1990662	cellular_component	S100A9 complex
LA	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
MA	0002523	biological_process	leukocyte migration involved in inflammatory response
MA	0002544	biological_process	chronic inflammatory response
MA	0005509	molecular_function	calcium ion binding
MA	0005515	molecular_function	protein binding
MA	0005576	cellular_component	extracellular region
MA	0005634	cellular_component	nucleus
MA	0005737	cellular_component	cytoplasm
MA	0005829	cellular_component	cytosol
MA	0005856	cellular_component	cytoskeleton
MA	0005886	cellular_component	plasma membrane
MA	0006914	biological_process	autophagy
MA	0006954	biological_process	inflammatory response
MA	0008017	molecular_function	microtubule binding
MA	0008270	molecular_function	zinc ion binding
MA	0010043	biological_process	response to zinc ion
MA	0018119	biological_process	peptidyl-cysteine S-nitrosylation
MA	0030307	biological_process	positive regulation of cell growth
MA	0030593	biological_process	neutrophil chemotaxis
MA	0031012	cellular_component	extracellular matrix
MA	0032496	biological_process	response to lipopolysaccharide
MA	0034121	biological_process	regulation of toll-like receptor signaling pathway
MA	0034774	cellular_component	secretory granule lumen
MA	0035425	biological_process	autocrine signaling
MA	0035662	molecular_function	Toll-like receptor 4 binding
MA	0042742	biological_process	defense response to bacterium
MA	0043542	biological_process	endothelial cell migration
MA	0045111	cellular_component	intermediate filament cytoskeleton
MA	0045471	biological_process	response to ethanol
MA	0048306	molecular_function	calcium-dependent protein binding
MA	0050544	molecular_function	arachidonate binding
MA	0050729	biological_process	positive regulation of inflammatory response
MA	0050786	molecular_function	RAGE receptor binding
MA	0050832	biological_process	defense response to fungus
MA	0051493	biological_process	regulation of cytoskeleton organization
MA	0070062	cellular_component	extracellular exosome
MA	0070488	biological_process	neutrophil aggregation
MA	1990660	cellular_component	calprotectin complex
MA	1990661	cellular_component	S100A8 complex
MA	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
NA	0002523	biological_process	leukocyte migration involved in inflammatory response
NA	0002544	biological_process	chronic inflammatory response
NA	0005509	molecular_function	calcium ion binding
NA	0005515	molecular_function	protein binding
NA	0005576	cellular_component	extracellular region
NA	0005634	cellular_component	nucleus
NA	0005737	cellular_component	cytoplasm
NA	0005829	cellular_component	cytosol
NA	0005856	cellular_component	cytoskeleton
NA	0005886	cellular_component	plasma membrane
NA	0006914	biological_process	autophagy
NA	0006954	biological_process	inflammatory response
NA	0007267	biological_process	cell-cell signaling
NA	0008017	molecular_function	microtubule binding
NA	0008270	molecular_function	zinc ion binding
NA	0010976	biological_process	positive regulation of neuron projection development
NA	0014002	biological_process	astrocyte development
NA	0030307	biological_process	positive regulation of cell growth
NA	0030593	biological_process	neutrophil chemotaxis
NA	0031012	cellular_component	extracellular matrix
NA	0034121	biological_process	regulation of toll-like receptor signaling pathway
NA	0034774	cellular_component	secretory granule lumen
NA	0035425	biological_process	autocrine signaling
NA	0035606	biological_process	peptidyl-cysteine S-trans-nitrosylation
NA	0035662	molecular_function	Toll-like receptor 4 binding
NA	0042742	biological_process	defense response to bacterium
NA	0043542	biological_process	endothelial cell migration
NA	0045111	cellular_component	intermediate filament cytoskeleton
NA	0048306	molecular_function	calcium-dependent protein binding
NA	0050544	molecular_function	arachidonate binding
NA	0050729	biological_process	positive regulation of inflammatory response
NA	0050786	molecular_function	RAGE receptor binding
NA	0050832	biological_process	defense response to fungus
NA	0051493	biological_process	regulation of cytoskeleton organization
NA	0060264	biological_process	regulation of respiratory burst involved in inflammatory response
NA	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
NA	0070062	cellular_component	extracellular exosome
NA	0070488	biological_process	neutrophil aggregation
NA	1990660	cellular_component	calprotectin complex
NA	1990662	cellular_component	S100A9 complex
NA	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
OA	0002523	biological_process	leukocyte migration involved in inflammatory response
OA	0002544	biological_process	chronic inflammatory response
OA	0005509	molecular_function	calcium ion binding
OA	0005515	molecular_function	protein binding
OA	0005576	cellular_component	extracellular region
OA	0005634	cellular_component	nucleus
OA	0005737	cellular_component	cytoplasm
OA	0005829	cellular_component	cytosol
OA	0005856	cellular_component	cytoskeleton
OA	0005886	cellular_component	plasma membrane
OA	0006914	biological_process	autophagy
OA	0006954	biological_process	inflammatory response
OA	0007267	biological_process	cell-cell signaling
OA	0008017	molecular_function	microtubule binding
OA	0008270	molecular_function	zinc ion binding
OA	0010976	biological_process	positive regulation of neuron projection development
OA	0014002	biological_process	astrocyte development
OA	0030307	biological_process	positive regulation of cell growth
OA	0030593	biological_process	neutrophil chemotaxis
OA	0031012	cellular_component	extracellular matrix
OA	0034121	biological_process	regulation of toll-like receptor signaling pathway
OA	0034774	cellular_component	secretory granule lumen
OA	0035425	biological_process	autocrine signaling
OA	0035606	biological_process	peptidyl-cysteine S-trans-nitrosylation
OA	0035662	molecular_function	Toll-like receptor 4 binding
OA	0042742	biological_process	defense response to bacterium
OA	0043542	biological_process	endothelial cell migration
OA	0045111	cellular_component	intermediate filament cytoskeleton
OA	0048306	molecular_function	calcium-dependent protein binding
OA	0050544	molecular_function	arachidonate binding
OA	0050729	biological_process	positive regulation of inflammatory response
OA	0050786	molecular_function	RAGE receptor binding
OA	0050832	biological_process	defense response to fungus
OA	0051493	biological_process	regulation of cytoskeleton organization
OA	0060264	biological_process	regulation of respiratory burst involved in inflammatory response
OA	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
OA	0070062	cellular_component	extracellular exosome
OA	0070488	biological_process	neutrophil aggregation
OA	1990660	cellular_component	calprotectin complex
OA	1990662	cellular_component	S100A9 complex
OA	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
PA	0002523	biological_process	leukocyte migration involved in inflammatory response
PA	0002544	biological_process	chronic inflammatory response
PA	0005509	molecular_function	calcium ion binding
PA	0005515	molecular_function	protein binding
PA	0005576	cellular_component	extracellular region
PA	0005634	cellular_component	nucleus
PA	0005737	cellular_component	cytoplasm
PA	0005829	cellular_component	cytosol
PA	0005856	cellular_component	cytoskeleton
PA	0005886	cellular_component	plasma membrane
PA	0006914	biological_process	autophagy
PA	0006954	biological_process	inflammatory response
PA	0008017	molecular_function	microtubule binding
PA	0008270	molecular_function	zinc ion binding
PA	0010043	biological_process	response to zinc ion
PA	0018119	biological_process	peptidyl-cysteine S-nitrosylation
PA	0030307	biological_process	positive regulation of cell growth
PA	0030593	biological_process	neutrophil chemotaxis
PA	0031012	cellular_component	extracellular matrix
PA	0032496	biological_process	response to lipopolysaccharide
PA	0034121	biological_process	regulation of toll-like receptor signaling pathway
PA	0034774	cellular_component	secretory granule lumen
PA	0035425	biological_process	autocrine signaling
PA	0035662	molecular_function	Toll-like receptor 4 binding
PA	0042742	biological_process	defense response to bacterium
PA	0043542	biological_process	endothelial cell migration
PA	0045111	cellular_component	intermediate filament cytoskeleton
PA	0045471	biological_process	response to ethanol
PA	0048306	molecular_function	calcium-dependent protein binding
PA	0050544	molecular_function	arachidonate binding
PA	0050729	biological_process	positive regulation of inflammatory response
PA	0050786	molecular_function	RAGE receptor binding
PA	0050832	biological_process	defense response to fungus
PA	0051493	biological_process	regulation of cytoskeleton organization
PA	0070062	cellular_component	extracellular exosome
PA	0070488	biological_process	neutrophil aggregation
PA	1990660	cellular_component	calprotectin complex
PA	1990661	cellular_component	S100A8 complex
PA	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DINTDGAVNfqEF

Chain	Residue	Details
A	ASP59-PHE71
B	ASP67-PHE79

---

site_id	PS00303
Number of Residues	22
Details	S100_CABP S-100/ICaBP type calcium binding protein signature. WFkeLDintDgavNFqEFlkLV

Chain	Residue	Details
A	TRP54-VAL75
B	ILE62-MET83

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	560
Details	Domain: {"description":"EF-hand 1","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	560
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	38
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Modified residue: {"description":"S-nitrosocysteine","evidences":[{"source":"PubMed","id":"18832721","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	72
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17553524","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	40
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11851337","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17553524","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IRJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XK4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	40
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11851337","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17553524","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IRJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XK4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	8
Details	Modified residue: {"description":"Pros-methylhistidine","evidences":[{"source":"UniProtKB","id":"P50116","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---