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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9OHS

Crystal structure of human FTO in complex with Ga(III) and ascorbate

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues11
DetailsRegion: {"description":"Loop L1; predicted to block binding of double-stranded DNA or RNA","evidences":[{"source":"PubMed","id":"20376003","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues6
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"20376003","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3LFM","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"20376003","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25452335","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3LFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4QKN","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"20376003","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25452335","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23547775","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25452335","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"26457839","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"28553460","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3LFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CXW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CXX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CXY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IDZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IE0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IE4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IE5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IE6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4QKN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZS2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZS3","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues2
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"20376003","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23547775","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25452335","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"26457839","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"28553460","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3LFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CXW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CXX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CXY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IDZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IE0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IE4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IE5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IE6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4QKN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZS2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZS3","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues3
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"20376003","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25452335","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26457839","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3LFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4QKN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZS2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZS3","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"20376003","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25452335","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26457839","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3LFM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4QKN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZS2","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues1
DetailsModified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

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PDB entries from 2026-03-04

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