9OHL

TRMT112-METTL5 bound to SAM and FWG-33B

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0001650	cellular_component	fibrillar center
C	0003676	molecular_function	nucleic acid binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005730	cellular_component	nucleolus
C	0005737	cellular_component	cytoplasm
C	0006364	biological_process	rRNA processing
C	0008168	molecular_function	methyltransferase activity
C	0008757	molecular_function	S-adenosylmethionine-dependent methyltransferase activity
C	0008988	molecular_function	rRNA (adenine-N6-)-methyltransferase activity
C	0016740	molecular_function	transferase activity
C	0031167	biological_process	rRNA methylation
C	0032259	biological_process	methylation
C	0036396	cellular_component	RNA N6-methyladenosine methyltransferase complex
C	0045727	biological_process	positive regulation of translation
C	0048863	biological_process	stem cell differentiation
C	0098793	cellular_component	presynapse
C	0098794	cellular_component	postsynapse
C	1904047	molecular_function	S-adenosyl-L-methionine binding
D	0000470	biological_process	maturation of LSU-rRNA
D	0001510	biological_process	RNA methylation
D	0002098	biological_process	tRNA wobble uridine modification
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006364	biological_process	rRNA processing
D	0008276	molecular_function	protein methyltransferase activity
D	0018364	biological_process	peptidyl-glutamine methylation
D	0030488	biological_process	tRNA methylation
D	0030490	biological_process	maturation of SSU-rRNA
D	0031167	biological_process	rRNA methylation
D	0032991	cellular_component	protein-containing complex
D	0034708	cellular_component	methyltransferase complex
D	0035097	cellular_component	histone methyltransferase complex
D	0036396	cellular_component	RNA N6-methyladenosine methyltransferase complex
D	0043527	cellular_component	tRNA methyltransferase complex
D	0043528	cellular_component	tRNA (m2G10) methyltransferase complex
D	0045815	biological_process	transcription initiation-coupled chromatin remodeling
D	0046982	molecular_function	protein heterodimerization activity
D	0048471	cellular_component	perinuclear region of cytoplasm
D	0070476	biological_process	rRNA (guanine-N7)-methylation
D	0141106	molecular_function	tRNA methyltransferase activator activity
D	2000234	biological_process	positive regulation of rRNA processing

Functional Information from PROSITE/UniProt

site_id	PS00092
Number of Residues	7
Details	N6_MTASE N-6 Adenine-specific DNA methylases signature. VIMNPPF

Chain	Residue	Details
C	VAL123-PHE129

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31328227","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6H2U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6H2V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31328227","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6H2U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31328227","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6H2V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	117
Details	Domain: {"description":"TRM112"}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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