Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9OFA

The structure of a Fungal Cyanide Hydratase from Gloeocercospora sorghi

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000257	molecular_function	nitrilase activity
A	0016836	molecular_function	hydro-lyase activity
A	0019500	biological_process	cyanide catabolic process
A	0030196	molecular_function	cyanide hydratase activity
B	0000257	molecular_function	nitrilase activity
B	0016836	molecular_function	hydro-lyase activity
B	0019500	biological_process	cyanide catabolic process
B	0030196	molecular_function	cyanide hydratase activity
C	0000257	molecular_function	nitrilase activity
C	0016836	molecular_function	hydro-lyase activity
C	0019500	biological_process	cyanide catabolic process
C	0030196	molecular_function	cyanide hydratase activity
D	0000257	molecular_function	nitrilase activity
D	0016836	molecular_function	hydro-lyase activity
D	0019500	biological_process	cyanide catabolic process
D	0030196	molecular_function	cyanide hydratase activity
E	0000257	molecular_function	nitrilase activity
E	0016836	molecular_function	hydro-lyase activity
E	0019500	biological_process	cyanide catabolic process
E	0030196	molecular_function	cyanide hydratase activity
F	0000257	molecular_function	nitrilase activity
F	0016836	molecular_function	hydro-lyase activity
F	0019500	biological_process	cyanide catabolic process
F	0030196	molecular_function	cyanide hydratase activity
G	0000257	molecular_function	nitrilase activity
G	0016836	molecular_function	hydro-lyase activity
G	0019500	biological_process	cyanide catabolic process
G	0030196	molecular_function	cyanide hydratase activity
H	0000257	molecular_function	nitrilase activity
H	0016836	molecular_function	hydro-lyase activity
H	0019500	biological_process	cyanide catabolic process
H	0030196	molecular_function	cyanide hydratase activity
I	0000257	molecular_function	nitrilase activity
I	0016836	molecular_function	hydro-lyase activity
I	0019500	biological_process	cyanide catabolic process
I	0030196	molecular_function	cyanide hydratase activity
J	0000257	molecular_function	nitrilase activity
J	0016836	molecular_function	hydro-lyase activity
J	0019500	biological_process	cyanide catabolic process
J	0030196	molecular_function	cyanide hydratase activity
K	0000257	molecular_function	nitrilase activity
K	0016836	molecular_function	hydro-lyase activity
K	0019500	biological_process	cyanide catabolic process
K	0030196	molecular_function	cyanide hydratase activity
L	0000257	molecular_function	nitrilase activity
L	0016836	molecular_function	hydro-lyase activity
L	0019500	biological_process	cyanide catabolic process
L	0030196	molecular_function	cyanide hydratase activity
M	0000257	molecular_function	nitrilase activity
M	0016836	molecular_function	hydro-lyase activity
M	0019500	biological_process	cyanide catabolic process
M	0030196	molecular_function	cyanide hydratase activity
N	0000257	molecular_function	nitrilase activity
N	0016836	molecular_function	hydro-lyase activity
N	0019500	biological_process	cyanide catabolic process
N	0030196	molecular_function	cyanide hydratase activity
O	0000257	molecular_function	nitrilase activity
O	0016836	molecular_function	hydro-lyase activity
O	0019500	biological_process	cyanide catabolic process
O	0030196	molecular_function	cyanide hydratase activity
P	0000257	molecular_function	nitrilase activity
P	0016836	molecular_function	hydro-lyase activity
P	0019500	biological_process	cyanide catabolic process
P	0030196	molecular_function	cyanide hydratase activity
Q	0000257	molecular_function	nitrilase activity
Q	0016836	molecular_function	hydro-lyase activity
Q	0019500	biological_process	cyanide catabolic process
Q	0030196	molecular_function	cyanide hydratase activity
R	0000257	molecular_function	nitrilase activity
R	0016836	molecular_function	hydro-lyase activity
R	0019500	biological_process	cyanide catabolic process
R	0030196	molecular_function	cyanide hydratase activity
S	0000257	molecular_function	nitrilase activity
S	0016836	molecular_function	hydro-lyase activity
S	0019500	biological_process	cyanide catabolic process
S	0030196	molecular_function	cyanide hydratase activity
T	0000257	molecular_function	nitrilase activity
T	0016836	molecular_function	hydro-lyase activity
T	0019500	biological_process	cyanide catabolic process
T	0030196	molecular_function	cyanide hydratase activity

Functional Information from PROSITE/UniProt

site_id	PS00920
Number of Residues	16
Details	NITRIL_CHT_1 Nitrilases / cyanide hydratase signature 1. GckLIaFpEvwIpGYP

Chain	Residue	Details
O	GLY38-PRO53

site_id	PS00921
Number of Residues	14
Details	NITRIL_CHT_2 Nitrilases / cyanide hydratase active site signature. GQlnCWENmnPFlK

Chain	Residue	Details
O	GLY159-LYS172

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5580
Details	Domain: {"description":"CN hydrolase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00054","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	40
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_03224","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"41709456","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	20
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"41709456","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	20
Details	Active site: {"description":"Nucleophile; alpha-thiohemiaminal intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_03224","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10587474","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)