Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9ODT

The structure of a Bacterial Cyanide Dihydratase from Bacillus safensis PER-URP-08

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000257	molecular_function	nitrilase activity
A	0004328	molecular_function	formamidase activity
A	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
A	0018822	molecular_function	nitrile hydratase activity
A	0019500	biological_process	cyanide catabolic process
A	0030196	molecular_function	cyanide hydratase activity
A	0051410	biological_process	detoxification of nitrogen compound
B	0000257	molecular_function	nitrilase activity
B	0004328	molecular_function	formamidase activity
B	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
B	0018822	molecular_function	nitrile hydratase activity
B	0019500	biological_process	cyanide catabolic process
B	0030196	molecular_function	cyanide hydratase activity
B	0051410	biological_process	detoxification of nitrogen compound
C	0000257	molecular_function	nitrilase activity
C	0004328	molecular_function	formamidase activity
C	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
C	0018822	molecular_function	nitrile hydratase activity
C	0019500	biological_process	cyanide catabolic process
C	0030196	molecular_function	cyanide hydratase activity
C	0051410	biological_process	detoxification of nitrogen compound
D	0000257	molecular_function	nitrilase activity
D	0004328	molecular_function	formamidase activity
D	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
D	0018822	molecular_function	nitrile hydratase activity
D	0019500	biological_process	cyanide catabolic process
D	0030196	molecular_function	cyanide hydratase activity
D	0051410	biological_process	detoxification of nitrogen compound
E	0000257	molecular_function	nitrilase activity
E	0004328	molecular_function	formamidase activity
E	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
E	0018822	molecular_function	nitrile hydratase activity
E	0019500	biological_process	cyanide catabolic process
E	0030196	molecular_function	cyanide hydratase activity
E	0051410	biological_process	detoxification of nitrogen compound
F	0000257	molecular_function	nitrilase activity
F	0004328	molecular_function	formamidase activity
F	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
F	0018822	molecular_function	nitrile hydratase activity
F	0019500	biological_process	cyanide catabolic process
F	0030196	molecular_function	cyanide hydratase activity
F	0051410	biological_process	detoxification of nitrogen compound
G	0000257	molecular_function	nitrilase activity
G	0004328	molecular_function	formamidase activity
G	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
G	0018822	molecular_function	nitrile hydratase activity
G	0019500	biological_process	cyanide catabolic process
G	0030196	molecular_function	cyanide hydratase activity
G	0051410	biological_process	detoxification of nitrogen compound
H	0000257	molecular_function	nitrilase activity
H	0004328	molecular_function	formamidase activity
H	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
H	0018822	molecular_function	nitrile hydratase activity
H	0019500	biological_process	cyanide catabolic process
H	0030196	molecular_function	cyanide hydratase activity
H	0051410	biological_process	detoxification of nitrogen compound
I	0000257	molecular_function	nitrilase activity
I	0004328	molecular_function	formamidase activity
I	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
I	0018822	molecular_function	nitrile hydratase activity
I	0019500	biological_process	cyanide catabolic process
I	0030196	molecular_function	cyanide hydratase activity
I	0051410	biological_process	detoxification of nitrogen compound
J	0000257	molecular_function	nitrilase activity
J	0004328	molecular_function	formamidase activity
J	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
J	0018822	molecular_function	nitrile hydratase activity
J	0019500	biological_process	cyanide catabolic process
J	0030196	molecular_function	cyanide hydratase activity
J	0051410	biological_process	detoxification of nitrogen compound
K	0000257	molecular_function	nitrilase activity
K	0004328	molecular_function	formamidase activity
K	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
K	0018822	molecular_function	nitrile hydratase activity
K	0019500	biological_process	cyanide catabolic process
K	0030196	molecular_function	cyanide hydratase activity
K	0051410	biological_process	detoxification of nitrogen compound
L	0000257	molecular_function	nitrilase activity
L	0004328	molecular_function	formamidase activity
L	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
L	0018822	molecular_function	nitrile hydratase activity
L	0019500	biological_process	cyanide catabolic process
L	0030196	molecular_function	cyanide hydratase activity
L	0051410	biological_process	detoxification of nitrogen compound
M	0000257	molecular_function	nitrilase activity
M	0004328	molecular_function	formamidase activity
M	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
M	0018822	molecular_function	nitrile hydratase activity
M	0019500	biological_process	cyanide catabolic process
M	0030196	molecular_function	cyanide hydratase activity
M	0051410	biological_process	detoxification of nitrogen compound
N	0000257	molecular_function	nitrilase activity
N	0004328	molecular_function	formamidase activity
N	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
N	0018822	molecular_function	nitrile hydratase activity
N	0019500	biological_process	cyanide catabolic process
N	0030196	molecular_function	cyanide hydratase activity
N	0051410	biological_process	detoxification of nitrogen compound
O	0000257	molecular_function	nitrilase activity
O	0004328	molecular_function	formamidase activity
O	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
O	0018822	molecular_function	nitrile hydratase activity
O	0019500	biological_process	cyanide catabolic process
O	0030196	molecular_function	cyanide hydratase activity
O	0051410	biological_process	detoxification of nitrogen compound
P	0000257	molecular_function	nitrilase activity
P	0004328	molecular_function	formamidase activity
P	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
P	0018822	molecular_function	nitrile hydratase activity
P	0019500	biological_process	cyanide catabolic process
P	0030196	molecular_function	cyanide hydratase activity
P	0051410	biological_process	detoxification of nitrogen compound
Q	0000257	molecular_function	nitrilase activity
Q	0004328	molecular_function	formamidase activity
Q	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Q	0018822	molecular_function	nitrile hydratase activity
Q	0019500	biological_process	cyanide catabolic process
Q	0030196	molecular_function	cyanide hydratase activity
Q	0051410	biological_process	detoxification of nitrogen compound
R	0000257	molecular_function	nitrilase activity
R	0004328	molecular_function	formamidase activity
R	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
R	0018822	molecular_function	nitrile hydratase activity
R	0019500	biological_process	cyanide catabolic process
R	0030196	molecular_function	cyanide hydratase activity
R	0051410	biological_process	detoxification of nitrogen compound

Functional Information from PROSITE/UniProt

site_id	PS00920
Number of Residues	16
Details	NITRIL_CHT_1 Nitrilases / cyanide hydratase signature 1. GakLVaFpEafLpGYP

Chain	Residue	Details
B	GLY40-PRO55

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4716
Details	Domain: {"description":"CN hydrolase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00054","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	36
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00054","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"41709456","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	18
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"41709456","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	18
Details	Active site: {"description":"Nucleophile; alpha-thiohemiaminal intermediate","evidences":[{"source":"PubMed","id":"41709456","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)