9OB0
Human PU.1 ETS-Domain (165-270) Bound to d(5'-AATAAGCGIAAGTGGG-3') d(5'-TCCCACTTTCGCTTAT-3') with an IT mismatch
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 83 |
| Details | DNA binding: {"description":"ETS","evidences":[{"source":"PROSITE-ProRule","id":"PRU00237","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"forms a salt bridge with the phosphate backbone of the opposite strand downstream of the GGAA core sequence","evidences":[{"source":"UniProtKB","id":"P17433","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"contacts bases in the GGAA sequence in the major groove","evidences":[{"source":"UniProtKB","id":"P17433","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"contacts the phosphate backbone of the GGAA sequence in the minor groove upstream","evidences":[{"source":"UniProtKB","id":"P17433","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
