9O9T
Structure of human MPC IMS-open
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005743 | cellular_component | mitochondrial inner membrane |
| A | 0006850 | biological_process | pyruvate import into mitochondria |
| A | 0050833 | molecular_function | pyruvate transmembrane transporter activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005743 | cellular_component | mitochondrial inner membrane |
| B | 0006850 | biological_process | pyruvate import into mitochondria |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0050833 | molecular_function | pyruvate transmembrane transporter activity |
| B | 7770001 | cellular_component | mitochondrial pyruvate carrier complex |
Functional Information from PROSITE/UniProt
| site_id | PS01037 |
| Number of Residues | 18 |
| Details | SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN |
| Chain | Residue | Details |
| A | PRO229-ASN246 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 37 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"40044865","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"40101766","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8YW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YW8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YW9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MO0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Topological domain: {"description":"Mitochondrial intermembrane","evidences":[{"source":"PubMed","id":"40044865","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"40101766","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27317664","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"8YW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YW8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YW9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MO0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"40044865","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"40101766","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8YW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YW8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YW9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MO0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Topological domain: {"description":"Mitochondrial matrix","evidences":[{"source":"PubMed","id":"40044865","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"40101766","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27317664","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"8YW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YW8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YW9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MO0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"40044865","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"40101766","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8YW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YW8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YW9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MO0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"40044865","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9MNY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 9 |
| Details | Topological domain: {"description":"Mitochondrial matrix","evidences":[{"source":"PubMed","id":"40044865","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"40101766","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8YW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YW8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YW9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9KNY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MNZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9MO0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P63030","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
