9O6S

Structure of the human prohibitin complex in the closed state

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000423	biological_process	mitophagy
A	0002639	biological_process	positive regulation of immunoglobulin production
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005741	cellular_component	mitochondrial outer membrane
A	0005743	cellular_component	mitochondrial inner membrane
A	0005886	cellular_component	plasma membrane
A	0006351	biological_process	DNA-templated transcription
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0006606	biological_process	protein import into nucleus
A	0007005	biological_process	mitochondrion organization
A	0007062	biological_process	sister chromatid cohesion
A	0009986	cellular_component	cell surface
A	0016020	cellular_component	membrane
A	0016363	cellular_component	nuclear matrix
A	0016477	biological_process	cell migration
A	0030331	molecular_function	nuclear estrogen receptor binding
A	0030449	biological_process	regulation of complement activation
A	0032991	cellular_component	protein-containing complex
A	0033218	molecular_function	amide binding
A	0035632	cellular_component	mitochondrial prohibitin complex
A	0039529	biological_process	RIG-I signaling pathway
A	0042113	biological_process	B cell activation
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0043066	biological_process	negative regulation of apoptotic process
A	0043410	biological_process	positive regulation of MAPK cascade
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0046625	molecular_function	sphingolipid binding
A	0046982	molecular_function	protein heterodimerization activity
A	0050821	biological_process	protein stabilization
A	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
A	0071944	cellular_component	cell periphery
A	0098800	cellular_component	inner mitochondrial membrane protein complex
A	0140374	biological_process	antiviral innate immune response
A	1900208	biological_process	regulation of cardiolipin metabolic process
A	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
B	0000122	biological_process	negative regulation of transcription by RNA polymerase II
B	0001649	biological_process	osteoblast differentiation
B	0001850	molecular_function	complement component C3a binding
B	0001851	molecular_function	complement component C3b binding
B	0002639	biological_process	positive regulation of immunoglobulin production
B	0003714	molecular_function	transcription corepressor activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005769	cellular_component	early endosome
B	0005886	cellular_component	plasma membrane
B	0006355	biological_process	regulation of DNA-templated transcription
B	0007005	biological_process	mitochondrion organization
B	0007165	biological_process	signal transduction
B	0008285	biological_process	negative regulation of cell population proliferation
B	0009986	cellular_component	cell surface
B	0010628	biological_process	positive regulation of gene expression
B	0010944	biological_process	negative regulation of transcription by competitive promoter binding
B	0016020	cellular_component	membrane
B	0019899	molecular_function	enzyme binding
B	0030308	biological_process	negative regulation of cell growth
B	0031871	molecular_function	proteinase activated receptor binding
B	0032740	biological_process	positive regulation of interleukin-17 production
B	0035632	cellular_component	mitochondrial prohibitin complex
B	0039529	biological_process	RIG-I signaling pathway
B	0040029	biological_process	epigenetic regulation of gene expression
B	0042113	biological_process	B cell activation
B	0042177	biological_process	negative regulation of protein catabolic process
B	0042826	molecular_function	histone deacetylase binding
B	0042981	biological_process	regulation of apoptotic process
B	0043525	biological_process	positive regulation of neuron apoptotic process
B	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
B	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0045893	biological_process	positive regulation of DNA-templated transcription
B	0045917	biological_process	positive regulation of complement activation
B	0046718	biological_process	symbiont entry into host cell
B	0046982	molecular_function	protein heterodimerization activity
B	0048661	biological_process	positive regulation of smooth muscle cell proliferation
B	0050821	biological_process	protein stabilization
B	0050847	biological_process	progesterone receptor signaling pathway
B	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
B	0060766	biological_process	negative regulation of androgen receptor signaling pathway
B	0070062	cellular_component	extracellular exosome
B	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
B	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
B	0071354	biological_process	cellular response to interleukin-6
B	0071897	biological_process	DNA biosynthetic process
B	0072538	biological_process	T-helper 17 type immune response
B	0140374	biological_process	antiviral innate immune response
B	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
B	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
C	0000423	biological_process	mitophagy
C	0002639	biological_process	positive regulation of immunoglobulin production
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005741	cellular_component	mitochondrial outer membrane
C	0005743	cellular_component	mitochondrial inner membrane
C	0005886	cellular_component	plasma membrane
C	0006351	biological_process	DNA-templated transcription
C	0006357	biological_process	regulation of transcription by RNA polymerase II
C	0006606	biological_process	protein import into nucleus
C	0007005	biological_process	mitochondrion organization
C	0007062	biological_process	sister chromatid cohesion
C	0009986	cellular_component	cell surface
C	0016020	cellular_component	membrane
C	0016363	cellular_component	nuclear matrix
C	0016477	biological_process	cell migration
C	0030331	molecular_function	nuclear estrogen receptor binding
C	0030449	biological_process	regulation of complement activation
C	0032991	cellular_component	protein-containing complex
C	0033218	molecular_function	amide binding
C	0035632	cellular_component	mitochondrial prohibitin complex
C	0039529	biological_process	RIG-I signaling pathway
C	0042113	biological_process	B cell activation
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0043066	biological_process	negative regulation of apoptotic process
C	0043410	biological_process	positive regulation of MAPK cascade
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0046625	molecular_function	sphingolipid binding
C	0046982	molecular_function	protein heterodimerization activity
C	0050821	biological_process	protein stabilization
C	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
C	0071944	cellular_component	cell periphery
C	0098800	cellular_component	inner mitochondrial membrane protein complex
C	0140374	biological_process	antiviral innate immune response
C	1900208	biological_process	regulation of cardiolipin metabolic process
C	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
D	0000122	biological_process	negative regulation of transcription by RNA polymerase II
D	0001649	biological_process	osteoblast differentiation
D	0001850	molecular_function	complement component C3a binding
D	0001851	molecular_function	complement component C3b binding
D	0002639	biological_process	positive regulation of immunoglobulin production
D	0003714	molecular_function	transcription corepressor activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005769	cellular_component	early endosome
D	0005886	cellular_component	plasma membrane
D	0006355	biological_process	regulation of DNA-templated transcription
D	0007005	biological_process	mitochondrion organization
D	0007165	biological_process	signal transduction
D	0008285	biological_process	negative regulation of cell population proliferation
D	0009986	cellular_component	cell surface
D	0010628	biological_process	positive regulation of gene expression
D	0010944	biological_process	negative regulation of transcription by competitive promoter binding
D	0016020	cellular_component	membrane
D	0019899	molecular_function	enzyme binding
D	0030308	biological_process	negative regulation of cell growth
D	0031871	molecular_function	proteinase activated receptor binding
D	0032740	biological_process	positive regulation of interleukin-17 production
D	0035632	cellular_component	mitochondrial prohibitin complex
D	0039529	biological_process	RIG-I signaling pathway
D	0040029	biological_process	epigenetic regulation of gene expression
D	0042113	biological_process	B cell activation
D	0042177	biological_process	negative regulation of protein catabolic process
D	0042826	molecular_function	histone deacetylase binding
D	0042981	biological_process	regulation of apoptotic process
D	0043525	biological_process	positive regulation of neuron apoptotic process
D	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
D	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0045893	biological_process	positive regulation of DNA-templated transcription
D	0045917	biological_process	positive regulation of complement activation
D	0046718	biological_process	symbiont entry into host cell
D	0046982	molecular_function	protein heterodimerization activity
D	0048661	biological_process	positive regulation of smooth muscle cell proliferation
D	0050821	biological_process	protein stabilization
D	0050847	biological_process	progesterone receptor signaling pathway
D	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
D	0060766	biological_process	negative regulation of androgen receptor signaling pathway
D	0070062	cellular_component	extracellular exosome
D	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
D	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
D	0071354	biological_process	cellular response to interleukin-6
D	0071897	biological_process	DNA biosynthetic process
D	0072538	biological_process	T-helper 17 type immune response
D	0140374	biological_process	antiviral innate immune response
D	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
D	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
E	0000423	biological_process	mitophagy
E	0002639	biological_process	positive regulation of immunoglobulin production
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005741	cellular_component	mitochondrial outer membrane
E	0005743	cellular_component	mitochondrial inner membrane
E	0005886	cellular_component	plasma membrane
E	0006351	biological_process	DNA-templated transcription
E	0006357	biological_process	regulation of transcription by RNA polymerase II
E	0006606	biological_process	protein import into nucleus
E	0007005	biological_process	mitochondrion organization
E	0007062	biological_process	sister chromatid cohesion
E	0009986	cellular_component	cell surface
E	0016020	cellular_component	membrane
E	0016363	cellular_component	nuclear matrix
E	0016477	biological_process	cell migration
E	0030331	molecular_function	nuclear estrogen receptor binding
E	0030449	biological_process	regulation of complement activation
E	0032991	cellular_component	protein-containing complex
E	0033218	molecular_function	amide binding
E	0035632	cellular_component	mitochondrial prohibitin complex
E	0039529	biological_process	RIG-I signaling pathway
E	0042113	biological_process	B cell activation
E	0042802	molecular_function	identical protein binding
E	0042803	molecular_function	protein homodimerization activity
E	0043066	biological_process	negative regulation of apoptotic process
E	0043410	biological_process	positive regulation of MAPK cascade
E	0045892	biological_process	negative regulation of DNA-templated transcription
E	0046625	molecular_function	sphingolipid binding
E	0046982	molecular_function	protein heterodimerization activity
E	0050821	biological_process	protein stabilization
E	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
E	0071944	cellular_component	cell periphery
E	0098800	cellular_component	inner mitochondrial membrane protein complex
E	0140374	biological_process	antiviral innate immune response
E	1900208	biological_process	regulation of cardiolipin metabolic process
E	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
F	0000122	biological_process	negative regulation of transcription by RNA polymerase II
F	0001649	biological_process	osteoblast differentiation
F	0001850	molecular_function	complement component C3a binding
F	0001851	molecular_function	complement component C3b binding
F	0002639	biological_process	positive regulation of immunoglobulin production
F	0003714	molecular_function	transcription corepressor activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005769	cellular_component	early endosome
F	0005886	cellular_component	plasma membrane
F	0006355	biological_process	regulation of DNA-templated transcription
F	0007005	biological_process	mitochondrion organization
F	0007165	biological_process	signal transduction
F	0008285	biological_process	negative regulation of cell population proliferation
F	0009986	cellular_component	cell surface
F	0010628	biological_process	positive regulation of gene expression
F	0010944	biological_process	negative regulation of transcription by competitive promoter binding
F	0016020	cellular_component	membrane
F	0019899	molecular_function	enzyme binding
F	0030308	biological_process	negative regulation of cell growth
F	0031871	molecular_function	proteinase activated receptor binding
F	0032740	biological_process	positive regulation of interleukin-17 production
F	0035632	cellular_component	mitochondrial prohibitin complex
F	0039529	biological_process	RIG-I signaling pathway
F	0040029	biological_process	epigenetic regulation of gene expression
F	0042113	biological_process	B cell activation
F	0042177	biological_process	negative regulation of protein catabolic process
F	0042826	molecular_function	histone deacetylase binding
F	0042981	biological_process	regulation of apoptotic process
F	0043525	biological_process	positive regulation of neuron apoptotic process
F	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
F	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
F	0045892	biological_process	negative regulation of DNA-templated transcription
F	0045893	biological_process	positive regulation of DNA-templated transcription
F	0045917	biological_process	positive regulation of complement activation
F	0046718	biological_process	symbiont entry into host cell
F	0046982	molecular_function	protein heterodimerization activity
F	0048661	biological_process	positive regulation of smooth muscle cell proliferation
F	0050821	biological_process	protein stabilization
F	0050847	biological_process	progesterone receptor signaling pathway
F	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
F	0060766	biological_process	negative regulation of androgen receptor signaling pathway
F	0070062	cellular_component	extracellular exosome
F	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
F	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
F	0071354	biological_process	cellular response to interleukin-6
F	0071897	biological_process	DNA biosynthetic process
F	0072538	biological_process	T-helper 17 type immune response
F	0140374	biological_process	antiviral innate immune response
F	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
F	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
G	0000423	biological_process	mitophagy
G	0002639	biological_process	positive regulation of immunoglobulin production
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005741	cellular_component	mitochondrial outer membrane
G	0005743	cellular_component	mitochondrial inner membrane
G	0005886	cellular_component	plasma membrane
G	0006351	biological_process	DNA-templated transcription
G	0006357	biological_process	regulation of transcription by RNA polymerase II
G	0006606	biological_process	protein import into nucleus
G	0007005	biological_process	mitochondrion organization
G	0007062	biological_process	sister chromatid cohesion
G	0009986	cellular_component	cell surface
G	0016020	cellular_component	membrane
G	0016363	cellular_component	nuclear matrix
G	0016477	biological_process	cell migration
G	0030331	molecular_function	nuclear estrogen receptor binding
G	0030449	biological_process	regulation of complement activation
G	0032991	cellular_component	protein-containing complex
G	0033218	molecular_function	amide binding
G	0035632	cellular_component	mitochondrial prohibitin complex
G	0039529	biological_process	RIG-I signaling pathway
G	0042113	biological_process	B cell activation
G	0042802	molecular_function	identical protein binding
G	0042803	molecular_function	protein homodimerization activity
G	0043066	biological_process	negative regulation of apoptotic process
G	0043410	biological_process	positive regulation of MAPK cascade
G	0045892	biological_process	negative regulation of DNA-templated transcription
G	0046625	molecular_function	sphingolipid binding
G	0046982	molecular_function	protein heterodimerization activity
G	0050821	biological_process	protein stabilization
G	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
G	0071944	cellular_component	cell periphery
G	0098800	cellular_component	inner mitochondrial membrane protein complex
G	0140374	biological_process	antiviral innate immune response
G	1900208	biological_process	regulation of cardiolipin metabolic process
G	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
H	0000122	biological_process	negative regulation of transcription by RNA polymerase II
H	0001649	biological_process	osteoblast differentiation
H	0001850	molecular_function	complement component C3a binding
H	0001851	molecular_function	complement component C3b binding
H	0002639	biological_process	positive regulation of immunoglobulin production
H	0003714	molecular_function	transcription corepressor activity
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0005769	cellular_component	early endosome
H	0005886	cellular_component	plasma membrane
H	0006355	biological_process	regulation of DNA-templated transcription
H	0007005	biological_process	mitochondrion organization
H	0007165	biological_process	signal transduction
H	0008285	biological_process	negative regulation of cell population proliferation
H	0009986	cellular_component	cell surface
H	0010628	biological_process	positive regulation of gene expression
H	0010944	biological_process	negative regulation of transcription by competitive promoter binding
H	0016020	cellular_component	membrane
H	0019899	molecular_function	enzyme binding
H	0030308	biological_process	negative regulation of cell growth
H	0031871	molecular_function	proteinase activated receptor binding
H	0032740	biological_process	positive regulation of interleukin-17 production
H	0035632	cellular_component	mitochondrial prohibitin complex
H	0039529	biological_process	RIG-I signaling pathway
H	0040029	biological_process	epigenetic regulation of gene expression
H	0042113	biological_process	B cell activation
H	0042177	biological_process	negative regulation of protein catabolic process
H	0042826	molecular_function	histone deacetylase binding
H	0042981	biological_process	regulation of apoptotic process
H	0043525	biological_process	positive regulation of neuron apoptotic process
H	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
H	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
H	0045892	biological_process	negative regulation of DNA-templated transcription
H	0045893	biological_process	positive regulation of DNA-templated transcription
H	0045917	biological_process	positive regulation of complement activation
H	0046718	biological_process	symbiont entry into host cell
H	0046982	molecular_function	protein heterodimerization activity
H	0048661	biological_process	positive regulation of smooth muscle cell proliferation
H	0050821	biological_process	protein stabilization
H	0050847	biological_process	progesterone receptor signaling pathway
H	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
H	0060766	biological_process	negative regulation of androgen receptor signaling pathway
H	0070062	cellular_component	extracellular exosome
H	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
H	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
H	0071354	biological_process	cellular response to interleukin-6
H	0071897	biological_process	DNA biosynthetic process
H	0072538	biological_process	T-helper 17 type immune response
H	0140374	biological_process	antiviral innate immune response
H	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
H	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
I	0000423	biological_process	mitophagy
I	0002639	biological_process	positive regulation of immunoglobulin production
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005741	cellular_component	mitochondrial outer membrane
I	0005743	cellular_component	mitochondrial inner membrane
I	0005886	cellular_component	plasma membrane
I	0006351	biological_process	DNA-templated transcription
I	0006357	biological_process	regulation of transcription by RNA polymerase II
I	0006606	biological_process	protein import into nucleus
I	0007005	biological_process	mitochondrion organization
I	0007062	biological_process	sister chromatid cohesion
I	0009986	cellular_component	cell surface
I	0016020	cellular_component	membrane
I	0016363	cellular_component	nuclear matrix
I	0016477	biological_process	cell migration
I	0030331	molecular_function	nuclear estrogen receptor binding
I	0030449	biological_process	regulation of complement activation
I	0032991	cellular_component	protein-containing complex
I	0033218	molecular_function	amide binding
I	0035632	cellular_component	mitochondrial prohibitin complex
I	0039529	biological_process	RIG-I signaling pathway
I	0042113	biological_process	B cell activation
I	0042802	molecular_function	identical protein binding
I	0042803	molecular_function	protein homodimerization activity
I	0043066	biological_process	negative regulation of apoptotic process
I	0043410	biological_process	positive regulation of MAPK cascade
I	0045892	biological_process	negative regulation of DNA-templated transcription
I	0046625	molecular_function	sphingolipid binding
I	0046982	molecular_function	protein heterodimerization activity
I	0050821	biological_process	protein stabilization
I	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
I	0071944	cellular_component	cell periphery
I	0098800	cellular_component	inner mitochondrial membrane protein complex
I	0140374	biological_process	antiviral innate immune response
I	1900208	biological_process	regulation of cardiolipin metabolic process
I	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
J	0000122	biological_process	negative regulation of transcription by RNA polymerase II
J	0001649	biological_process	osteoblast differentiation
J	0001850	molecular_function	complement component C3a binding
J	0001851	molecular_function	complement component C3b binding
J	0002639	biological_process	positive regulation of immunoglobulin production
J	0003714	molecular_function	transcription corepressor activity
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0005769	cellular_component	early endosome
J	0005886	cellular_component	plasma membrane
J	0006355	biological_process	regulation of DNA-templated transcription
J	0007005	biological_process	mitochondrion organization
J	0007165	biological_process	signal transduction
J	0008285	biological_process	negative regulation of cell population proliferation
J	0009986	cellular_component	cell surface
J	0010628	biological_process	positive regulation of gene expression
J	0010944	biological_process	negative regulation of transcription by competitive promoter binding
J	0016020	cellular_component	membrane
J	0019899	molecular_function	enzyme binding
J	0030308	biological_process	negative regulation of cell growth
J	0031871	molecular_function	proteinase activated receptor binding
J	0032740	biological_process	positive regulation of interleukin-17 production
J	0035632	cellular_component	mitochondrial prohibitin complex
J	0039529	biological_process	RIG-I signaling pathway
J	0040029	biological_process	epigenetic regulation of gene expression
J	0042113	biological_process	B cell activation
J	0042177	biological_process	negative regulation of protein catabolic process
J	0042826	molecular_function	histone deacetylase binding
J	0042981	biological_process	regulation of apoptotic process
J	0043525	biological_process	positive regulation of neuron apoptotic process
J	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
J	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
J	0045892	biological_process	negative regulation of DNA-templated transcription
J	0045893	biological_process	positive regulation of DNA-templated transcription
J	0045917	biological_process	positive regulation of complement activation
J	0046718	biological_process	symbiont entry into host cell
J	0046982	molecular_function	protein heterodimerization activity
J	0048661	biological_process	positive regulation of smooth muscle cell proliferation
J	0050821	biological_process	protein stabilization
J	0050847	biological_process	progesterone receptor signaling pathway
J	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
J	0060766	biological_process	negative regulation of androgen receptor signaling pathway
J	0070062	cellular_component	extracellular exosome
J	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
J	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
J	0071354	biological_process	cellular response to interleukin-6
J	0071897	biological_process	DNA biosynthetic process
J	0072538	biological_process	T-helper 17 type immune response
J	0140374	biological_process	antiviral innate immune response
J	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
J	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
K	0000423	biological_process	mitophagy
K	0002639	biological_process	positive regulation of immunoglobulin production
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005741	cellular_component	mitochondrial outer membrane
K	0005743	cellular_component	mitochondrial inner membrane
K	0005886	cellular_component	plasma membrane
K	0006351	biological_process	DNA-templated transcription
K	0006357	biological_process	regulation of transcription by RNA polymerase II
K	0006606	biological_process	protein import into nucleus
K	0007005	biological_process	mitochondrion organization
K	0007062	biological_process	sister chromatid cohesion
K	0009986	cellular_component	cell surface
K	0016020	cellular_component	membrane
K	0016363	cellular_component	nuclear matrix
K	0016477	biological_process	cell migration
K	0030331	molecular_function	nuclear estrogen receptor binding
K	0030449	biological_process	regulation of complement activation
K	0032991	cellular_component	protein-containing complex
K	0033218	molecular_function	amide binding
K	0035632	cellular_component	mitochondrial prohibitin complex
K	0039529	biological_process	RIG-I signaling pathway
K	0042113	biological_process	B cell activation
K	0042802	molecular_function	identical protein binding
K	0042803	molecular_function	protein homodimerization activity
K	0043066	biological_process	negative regulation of apoptotic process
K	0043410	biological_process	positive regulation of MAPK cascade
K	0045892	biological_process	negative regulation of DNA-templated transcription
K	0046625	molecular_function	sphingolipid binding
K	0046982	molecular_function	protein heterodimerization activity
K	0050821	biological_process	protein stabilization
K	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
K	0071944	cellular_component	cell periphery
K	0098800	cellular_component	inner mitochondrial membrane protein complex
K	0140374	biological_process	antiviral innate immune response
K	1900208	biological_process	regulation of cardiolipin metabolic process
K	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
L	0000122	biological_process	negative regulation of transcription by RNA polymerase II
L	0001649	biological_process	osteoblast differentiation
L	0001850	molecular_function	complement component C3a binding
L	0001851	molecular_function	complement component C3b binding
L	0002639	biological_process	positive regulation of immunoglobulin production
L	0003714	molecular_function	transcription corepressor activity
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0005769	cellular_component	early endosome
L	0005886	cellular_component	plasma membrane
L	0006355	biological_process	regulation of DNA-templated transcription
L	0007005	biological_process	mitochondrion organization
L	0007165	biological_process	signal transduction
L	0008285	biological_process	negative regulation of cell population proliferation
L	0009986	cellular_component	cell surface
L	0010628	biological_process	positive regulation of gene expression
L	0010944	biological_process	negative regulation of transcription by competitive promoter binding
L	0016020	cellular_component	membrane
L	0019899	molecular_function	enzyme binding
L	0030308	biological_process	negative regulation of cell growth
L	0031871	molecular_function	proteinase activated receptor binding
L	0032740	biological_process	positive regulation of interleukin-17 production
L	0035632	cellular_component	mitochondrial prohibitin complex
L	0039529	biological_process	RIG-I signaling pathway
L	0040029	biological_process	epigenetic regulation of gene expression
L	0042113	biological_process	B cell activation
L	0042177	biological_process	negative regulation of protein catabolic process
L	0042826	molecular_function	histone deacetylase binding
L	0042981	biological_process	regulation of apoptotic process
L	0043525	biological_process	positive regulation of neuron apoptotic process
L	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
L	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
L	0045892	biological_process	negative regulation of DNA-templated transcription
L	0045893	biological_process	positive regulation of DNA-templated transcription
L	0045917	biological_process	positive regulation of complement activation
L	0046718	biological_process	symbiont entry into host cell
L	0046982	molecular_function	protein heterodimerization activity
L	0048661	biological_process	positive regulation of smooth muscle cell proliferation
L	0050821	biological_process	protein stabilization
L	0050847	biological_process	progesterone receptor signaling pathway
L	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
L	0060766	biological_process	negative regulation of androgen receptor signaling pathway
L	0070062	cellular_component	extracellular exosome
L	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
L	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
L	0071354	biological_process	cellular response to interleukin-6
L	0071897	biological_process	DNA biosynthetic process
L	0072538	biological_process	T-helper 17 type immune response
L	0140374	biological_process	antiviral innate immune response
L	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
L	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
M	0000423	biological_process	mitophagy
M	0002639	biological_process	positive regulation of immunoglobulin production
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005737	cellular_component	cytoplasm
M	0005739	cellular_component	mitochondrion
M	0005741	cellular_component	mitochondrial outer membrane
M	0005743	cellular_component	mitochondrial inner membrane
M	0005886	cellular_component	plasma membrane
M	0006351	biological_process	DNA-templated transcription
M	0006357	biological_process	regulation of transcription by RNA polymerase II
M	0006606	biological_process	protein import into nucleus
M	0007005	biological_process	mitochondrion organization
M	0007062	biological_process	sister chromatid cohesion
M	0009986	cellular_component	cell surface
M	0016020	cellular_component	membrane
M	0016363	cellular_component	nuclear matrix
M	0016477	biological_process	cell migration
M	0030331	molecular_function	nuclear estrogen receptor binding
M	0030449	biological_process	regulation of complement activation
M	0032991	cellular_component	protein-containing complex
M	0033218	molecular_function	amide binding
M	0035632	cellular_component	mitochondrial prohibitin complex
M	0039529	biological_process	RIG-I signaling pathway
M	0042113	biological_process	B cell activation
M	0042802	molecular_function	identical protein binding
M	0042803	molecular_function	protein homodimerization activity
M	0043066	biological_process	negative regulation of apoptotic process
M	0043410	biological_process	positive regulation of MAPK cascade
M	0045892	biological_process	negative regulation of DNA-templated transcription
M	0046625	molecular_function	sphingolipid binding
M	0046982	molecular_function	protein heterodimerization activity
M	0050821	biological_process	protein stabilization
M	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
M	0071944	cellular_component	cell periphery
M	0098800	cellular_component	inner mitochondrial membrane protein complex
M	0140374	biological_process	antiviral innate immune response
M	1900208	biological_process	regulation of cardiolipin metabolic process
M	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
N	0000122	biological_process	negative regulation of transcription by RNA polymerase II
N	0001649	biological_process	osteoblast differentiation
N	0001850	molecular_function	complement component C3a binding
N	0001851	molecular_function	complement component C3b binding
N	0002639	biological_process	positive regulation of immunoglobulin production
N	0003714	molecular_function	transcription corepressor activity
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005737	cellular_component	cytoplasm
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0005769	cellular_component	early endosome
N	0005886	cellular_component	plasma membrane
N	0006355	biological_process	regulation of DNA-templated transcription
N	0007005	biological_process	mitochondrion organization
N	0007165	biological_process	signal transduction
N	0008285	biological_process	negative regulation of cell population proliferation
N	0009986	cellular_component	cell surface
N	0010628	biological_process	positive regulation of gene expression
N	0010944	biological_process	negative regulation of transcription by competitive promoter binding
N	0016020	cellular_component	membrane
N	0019899	molecular_function	enzyme binding
N	0030308	biological_process	negative regulation of cell growth
N	0031871	molecular_function	proteinase activated receptor binding
N	0032740	biological_process	positive regulation of interleukin-17 production
N	0035632	cellular_component	mitochondrial prohibitin complex
N	0039529	biological_process	RIG-I signaling pathway
N	0040029	biological_process	epigenetic regulation of gene expression
N	0042113	biological_process	B cell activation
N	0042177	biological_process	negative regulation of protein catabolic process
N	0042826	molecular_function	histone deacetylase binding
N	0042981	biological_process	regulation of apoptotic process
N	0043525	biological_process	positive regulation of neuron apoptotic process
N	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
N	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
N	0045892	biological_process	negative regulation of DNA-templated transcription
N	0045893	biological_process	positive regulation of DNA-templated transcription
N	0045917	biological_process	positive regulation of complement activation
N	0046718	biological_process	symbiont entry into host cell
N	0046982	molecular_function	protein heterodimerization activity
N	0048661	biological_process	positive regulation of smooth muscle cell proliferation
N	0050821	biological_process	protein stabilization
N	0050847	biological_process	progesterone receptor signaling pathway
N	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
N	0060766	biological_process	negative regulation of androgen receptor signaling pathway
N	0070062	cellular_component	extracellular exosome
N	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
N	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
N	0071354	biological_process	cellular response to interleukin-6
N	0071897	biological_process	DNA biosynthetic process
N	0072538	biological_process	T-helper 17 type immune response
N	0140374	biological_process	antiviral innate immune response
N	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
N	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
O	0000423	biological_process	mitophagy
O	0002639	biological_process	positive regulation of immunoglobulin production
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005737	cellular_component	cytoplasm
O	0005739	cellular_component	mitochondrion
O	0005741	cellular_component	mitochondrial outer membrane
O	0005743	cellular_component	mitochondrial inner membrane
O	0005886	cellular_component	plasma membrane
O	0006351	biological_process	DNA-templated transcription
O	0006357	biological_process	regulation of transcription by RNA polymerase II
O	0006606	biological_process	protein import into nucleus
O	0007005	biological_process	mitochondrion organization
O	0007062	biological_process	sister chromatid cohesion
O	0009986	cellular_component	cell surface
O	0016020	cellular_component	membrane
O	0016363	cellular_component	nuclear matrix
O	0016477	biological_process	cell migration
O	0030331	molecular_function	nuclear estrogen receptor binding
O	0030449	biological_process	regulation of complement activation
O	0032991	cellular_component	protein-containing complex
O	0033218	molecular_function	amide binding
O	0035632	cellular_component	mitochondrial prohibitin complex
O	0039529	biological_process	RIG-I signaling pathway
O	0042113	biological_process	B cell activation
O	0042802	molecular_function	identical protein binding
O	0042803	molecular_function	protein homodimerization activity
O	0043066	biological_process	negative regulation of apoptotic process
O	0043410	biological_process	positive regulation of MAPK cascade
O	0045892	biological_process	negative regulation of DNA-templated transcription
O	0046625	molecular_function	sphingolipid binding
O	0046982	molecular_function	protein heterodimerization activity
O	0050821	biological_process	protein stabilization
O	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
O	0071944	cellular_component	cell periphery
O	0098800	cellular_component	inner mitochondrial membrane protein complex
O	0140374	biological_process	antiviral innate immune response
O	1900208	biological_process	regulation of cardiolipin metabolic process
O	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
P	0000122	biological_process	negative regulation of transcription by RNA polymerase II
P	0001649	biological_process	osteoblast differentiation
P	0001850	molecular_function	complement component C3a binding
P	0001851	molecular_function	complement component C3b binding
P	0002639	biological_process	positive regulation of immunoglobulin production
P	0003714	molecular_function	transcription corepressor activity
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0005769	cellular_component	early endosome
P	0005886	cellular_component	plasma membrane
P	0006355	biological_process	regulation of DNA-templated transcription
P	0007005	biological_process	mitochondrion organization
P	0007165	biological_process	signal transduction
P	0008285	biological_process	negative regulation of cell population proliferation
P	0009986	cellular_component	cell surface
P	0010628	biological_process	positive regulation of gene expression
P	0010944	biological_process	negative regulation of transcription by competitive promoter binding
P	0016020	cellular_component	membrane
P	0019899	molecular_function	enzyme binding
P	0030308	biological_process	negative regulation of cell growth
P	0031871	molecular_function	proteinase activated receptor binding
P	0032740	biological_process	positive regulation of interleukin-17 production
P	0035632	cellular_component	mitochondrial prohibitin complex
P	0039529	biological_process	RIG-I signaling pathway
P	0040029	biological_process	epigenetic regulation of gene expression
P	0042113	biological_process	B cell activation
P	0042177	biological_process	negative regulation of protein catabolic process
P	0042826	molecular_function	histone deacetylase binding
P	0042981	biological_process	regulation of apoptotic process
P	0043525	biological_process	positive regulation of neuron apoptotic process
P	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
P	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
P	0045892	biological_process	negative regulation of DNA-templated transcription
P	0045893	biological_process	positive regulation of DNA-templated transcription
P	0045917	biological_process	positive regulation of complement activation
P	0046718	biological_process	symbiont entry into host cell
P	0046982	molecular_function	protein heterodimerization activity
P	0048661	biological_process	positive regulation of smooth muscle cell proliferation
P	0050821	biological_process	protein stabilization
P	0050847	biological_process	progesterone receptor signaling pathway
P	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
P	0060766	biological_process	negative regulation of androgen receptor signaling pathway
P	0070062	cellular_component	extracellular exosome
P	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
P	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
P	0071354	biological_process	cellular response to interleukin-6
P	0071897	biological_process	DNA biosynthetic process
P	0072538	biological_process	T-helper 17 type immune response
P	0140374	biological_process	antiviral innate immune response
P	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
P	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
Q	0000423	biological_process	mitophagy
Q	0002639	biological_process	positive regulation of immunoglobulin production
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005737	cellular_component	cytoplasm
Q	0005739	cellular_component	mitochondrion
Q	0005741	cellular_component	mitochondrial outer membrane
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0005886	cellular_component	plasma membrane
Q	0006351	biological_process	DNA-templated transcription
Q	0006357	biological_process	regulation of transcription by RNA polymerase II
Q	0006606	biological_process	protein import into nucleus
Q	0007005	biological_process	mitochondrion organization
Q	0007062	biological_process	sister chromatid cohesion
Q	0009986	cellular_component	cell surface
Q	0016020	cellular_component	membrane
Q	0016363	cellular_component	nuclear matrix
Q	0016477	biological_process	cell migration
Q	0030331	molecular_function	nuclear estrogen receptor binding
Q	0030449	biological_process	regulation of complement activation
Q	0032991	cellular_component	protein-containing complex
Q	0033218	molecular_function	amide binding
Q	0035632	cellular_component	mitochondrial prohibitin complex
Q	0039529	biological_process	RIG-I signaling pathway
Q	0042113	biological_process	B cell activation
Q	0042802	molecular_function	identical protein binding
Q	0042803	molecular_function	protein homodimerization activity
Q	0043066	biological_process	negative regulation of apoptotic process
Q	0043410	biological_process	positive regulation of MAPK cascade
Q	0045892	biological_process	negative regulation of DNA-templated transcription
Q	0046625	molecular_function	sphingolipid binding
Q	0046982	molecular_function	protein heterodimerization activity
Q	0050821	biological_process	protein stabilization
Q	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
Q	0071944	cellular_component	cell periphery
Q	0098800	cellular_component	inner mitochondrial membrane protein complex
Q	0140374	biological_process	antiviral innate immune response
Q	1900208	biological_process	regulation of cardiolipin metabolic process
Q	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
R	0000122	biological_process	negative regulation of transcription by RNA polymerase II
R	0001649	biological_process	osteoblast differentiation
R	0001850	molecular_function	complement component C3a binding
R	0001851	molecular_function	complement component C3b binding
R	0002639	biological_process	positive regulation of immunoglobulin production
R	0003714	molecular_function	transcription corepressor activity
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0005739	cellular_component	mitochondrion
R	0005743	cellular_component	mitochondrial inner membrane
R	0005769	cellular_component	early endosome
R	0005886	cellular_component	plasma membrane
R	0006355	biological_process	regulation of DNA-templated transcription
R	0007005	biological_process	mitochondrion organization
R	0007165	biological_process	signal transduction
R	0008285	biological_process	negative regulation of cell population proliferation
R	0009986	cellular_component	cell surface
R	0010628	biological_process	positive regulation of gene expression
R	0010944	biological_process	negative regulation of transcription by competitive promoter binding
R	0016020	cellular_component	membrane
R	0019899	molecular_function	enzyme binding
R	0030308	biological_process	negative regulation of cell growth
R	0031871	molecular_function	proteinase activated receptor binding
R	0032740	biological_process	positive regulation of interleukin-17 production
R	0035632	cellular_component	mitochondrial prohibitin complex
R	0039529	biological_process	RIG-I signaling pathway
R	0040029	biological_process	epigenetic regulation of gene expression
R	0042113	biological_process	B cell activation
R	0042177	biological_process	negative regulation of protein catabolic process
R	0042826	molecular_function	histone deacetylase binding
R	0042981	biological_process	regulation of apoptotic process
R	0043525	biological_process	positive regulation of neuron apoptotic process
R	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
R	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
R	0045892	biological_process	negative regulation of DNA-templated transcription
R	0045893	biological_process	positive regulation of DNA-templated transcription
R	0045917	biological_process	positive regulation of complement activation
R	0046718	biological_process	symbiont entry into host cell
R	0046982	molecular_function	protein heterodimerization activity
R	0048661	biological_process	positive regulation of smooth muscle cell proliferation
R	0050821	biological_process	protein stabilization
R	0050847	biological_process	progesterone receptor signaling pathway
R	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
R	0060766	biological_process	negative regulation of androgen receptor signaling pathway
R	0070062	cellular_component	extracellular exosome
R	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
R	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
R	0071354	biological_process	cellular response to interleukin-6
R	0071897	biological_process	DNA biosynthetic process
R	0072538	biological_process	T-helper 17 type immune response
R	0140374	biological_process	antiviral innate immune response
R	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
R	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
S	0000423	biological_process	mitophagy
S	0002639	biological_process	positive regulation of immunoglobulin production
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005737	cellular_component	cytoplasm
S	0005739	cellular_component	mitochondrion
S	0005741	cellular_component	mitochondrial outer membrane
S	0005743	cellular_component	mitochondrial inner membrane
S	0005886	cellular_component	plasma membrane
S	0006351	biological_process	DNA-templated transcription
S	0006357	biological_process	regulation of transcription by RNA polymerase II
S	0006606	biological_process	protein import into nucleus
S	0007005	biological_process	mitochondrion organization
S	0007062	biological_process	sister chromatid cohesion
S	0009986	cellular_component	cell surface
S	0016020	cellular_component	membrane
S	0016363	cellular_component	nuclear matrix
S	0016477	biological_process	cell migration
S	0030331	molecular_function	nuclear estrogen receptor binding
S	0030449	biological_process	regulation of complement activation
S	0032991	cellular_component	protein-containing complex
S	0033218	molecular_function	amide binding
S	0035632	cellular_component	mitochondrial prohibitin complex
S	0039529	biological_process	RIG-I signaling pathway
S	0042113	biological_process	B cell activation
S	0042802	molecular_function	identical protein binding
S	0042803	molecular_function	protein homodimerization activity
S	0043066	biological_process	negative regulation of apoptotic process
S	0043410	biological_process	positive regulation of MAPK cascade
S	0045892	biological_process	negative regulation of DNA-templated transcription
S	0046625	molecular_function	sphingolipid binding
S	0046982	molecular_function	protein heterodimerization activity
S	0050821	biological_process	protein stabilization
S	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
S	0071944	cellular_component	cell periphery
S	0098800	cellular_component	inner mitochondrial membrane protein complex
S	0140374	biological_process	antiviral innate immune response
S	1900208	biological_process	regulation of cardiolipin metabolic process
S	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
T	0000122	biological_process	negative regulation of transcription by RNA polymerase II
T	0001649	biological_process	osteoblast differentiation
T	0001850	molecular_function	complement component C3a binding
T	0001851	molecular_function	complement component C3b binding
T	0002639	biological_process	positive regulation of immunoglobulin production
T	0003714	molecular_function	transcription corepressor activity
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005737	cellular_component	cytoplasm
T	0005739	cellular_component	mitochondrion
T	0005743	cellular_component	mitochondrial inner membrane
T	0005769	cellular_component	early endosome
T	0005886	cellular_component	plasma membrane
T	0006355	biological_process	regulation of DNA-templated transcription
T	0007005	biological_process	mitochondrion organization
T	0007165	biological_process	signal transduction
T	0008285	biological_process	negative regulation of cell population proliferation
T	0009986	cellular_component	cell surface
T	0010628	biological_process	positive regulation of gene expression
T	0010944	biological_process	negative regulation of transcription by competitive promoter binding
T	0016020	cellular_component	membrane
T	0019899	molecular_function	enzyme binding
T	0030308	biological_process	negative regulation of cell growth
T	0031871	molecular_function	proteinase activated receptor binding
T	0032740	biological_process	positive regulation of interleukin-17 production
T	0035632	cellular_component	mitochondrial prohibitin complex
T	0039529	biological_process	RIG-I signaling pathway
T	0040029	biological_process	epigenetic regulation of gene expression
T	0042113	biological_process	B cell activation
T	0042177	biological_process	negative regulation of protein catabolic process
T	0042826	molecular_function	histone deacetylase binding
T	0042981	biological_process	regulation of apoptotic process
T	0043525	biological_process	positive regulation of neuron apoptotic process
T	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
T	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
T	0045892	biological_process	negative regulation of DNA-templated transcription
T	0045893	biological_process	positive regulation of DNA-templated transcription
T	0045917	biological_process	positive regulation of complement activation
T	0046718	biological_process	symbiont entry into host cell
T	0046982	molecular_function	protein heterodimerization activity
T	0048661	biological_process	positive regulation of smooth muscle cell proliferation
T	0050821	biological_process	protein stabilization
T	0050847	biological_process	progesterone receptor signaling pathway
T	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
T	0060766	biological_process	negative regulation of androgen receptor signaling pathway
T	0070062	cellular_component	extracellular exosome
T	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
T	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
T	0071354	biological_process	cellular response to interleukin-6
T	0071897	biological_process	DNA biosynthetic process
T	0072538	biological_process	T-helper 17 type immune response
T	0140374	biological_process	antiviral innate immune response
T	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
T	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
U	0000423	biological_process	mitophagy
U	0002639	biological_process	positive regulation of immunoglobulin production
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005737	cellular_component	cytoplasm
U	0005739	cellular_component	mitochondrion
U	0005741	cellular_component	mitochondrial outer membrane
U	0005743	cellular_component	mitochondrial inner membrane
U	0005886	cellular_component	plasma membrane
U	0006351	biological_process	DNA-templated transcription
U	0006357	biological_process	regulation of transcription by RNA polymerase II
U	0006606	biological_process	protein import into nucleus
U	0007005	biological_process	mitochondrion organization
U	0007062	biological_process	sister chromatid cohesion
U	0009986	cellular_component	cell surface
U	0016020	cellular_component	membrane
U	0016363	cellular_component	nuclear matrix
U	0016477	biological_process	cell migration
U	0030331	molecular_function	nuclear estrogen receptor binding
U	0030449	biological_process	regulation of complement activation
U	0032991	cellular_component	protein-containing complex
U	0033218	molecular_function	amide binding
U	0035632	cellular_component	mitochondrial prohibitin complex
U	0039529	biological_process	RIG-I signaling pathway
U	0042113	biological_process	B cell activation
U	0042802	molecular_function	identical protein binding
U	0042803	molecular_function	protein homodimerization activity
U	0043066	biological_process	negative regulation of apoptotic process
U	0043410	biological_process	positive regulation of MAPK cascade
U	0045892	biological_process	negative regulation of DNA-templated transcription
U	0046625	molecular_function	sphingolipid binding
U	0046982	molecular_function	protein heterodimerization activity
U	0050821	biological_process	protein stabilization
U	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
U	0071944	cellular_component	cell periphery
U	0098800	cellular_component	inner mitochondrial membrane protein complex
U	0140374	biological_process	antiviral innate immune response
U	1900208	biological_process	regulation of cardiolipin metabolic process
U	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
V	0000122	biological_process	negative regulation of transcription by RNA polymerase II
V	0001649	biological_process	osteoblast differentiation
V	0001850	molecular_function	complement component C3a binding
V	0001851	molecular_function	complement component C3b binding
V	0002639	biological_process	positive regulation of immunoglobulin production
V	0003714	molecular_function	transcription corepressor activity
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005737	cellular_component	cytoplasm
V	0005739	cellular_component	mitochondrion
V	0005743	cellular_component	mitochondrial inner membrane
V	0005769	cellular_component	early endosome
V	0005886	cellular_component	plasma membrane
V	0006355	biological_process	regulation of DNA-templated transcription
V	0007005	biological_process	mitochondrion organization
V	0007165	biological_process	signal transduction
V	0008285	biological_process	negative regulation of cell population proliferation
V	0009986	cellular_component	cell surface
V	0010628	biological_process	positive regulation of gene expression
V	0010944	biological_process	negative regulation of transcription by competitive promoter binding
V	0016020	cellular_component	membrane
V	0019899	molecular_function	enzyme binding
V	0030308	biological_process	negative regulation of cell growth
V	0031871	molecular_function	proteinase activated receptor binding
V	0032740	biological_process	positive regulation of interleukin-17 production
V	0035632	cellular_component	mitochondrial prohibitin complex
V	0039529	biological_process	RIG-I signaling pathway
V	0040029	biological_process	epigenetic regulation of gene expression
V	0042113	biological_process	B cell activation
V	0042177	biological_process	negative regulation of protein catabolic process
V	0042826	molecular_function	histone deacetylase binding
V	0042981	biological_process	regulation of apoptotic process
V	0043525	biological_process	positive regulation of neuron apoptotic process
V	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
V	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
V	0045892	biological_process	negative regulation of DNA-templated transcription
V	0045893	biological_process	positive regulation of DNA-templated transcription
V	0045917	biological_process	positive regulation of complement activation
V	0046718	biological_process	symbiont entry into host cell
V	0046982	molecular_function	protein heterodimerization activity
V	0048661	biological_process	positive regulation of smooth muscle cell proliferation
V	0050821	biological_process	protein stabilization
V	0050847	biological_process	progesterone receptor signaling pathway
V	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
V	0060766	biological_process	negative regulation of androgen receptor signaling pathway
V	0070062	cellular_component	extracellular exosome
V	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
V	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
V	0071354	biological_process	cellular response to interleukin-6
V	0071897	biological_process	DNA biosynthetic process
V	0072538	biological_process	T-helper 17 type immune response
V	0140374	biological_process	antiviral innate immune response
V	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
V	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
W	0000423	biological_process	mitophagy
W	0002639	biological_process	positive regulation of immunoglobulin production
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005737	cellular_component	cytoplasm
W	0005739	cellular_component	mitochondrion
W	0005741	cellular_component	mitochondrial outer membrane
W	0005743	cellular_component	mitochondrial inner membrane
W	0005886	cellular_component	plasma membrane
W	0006351	biological_process	DNA-templated transcription
W	0006357	biological_process	regulation of transcription by RNA polymerase II
W	0006606	biological_process	protein import into nucleus
W	0007005	biological_process	mitochondrion organization
W	0007062	biological_process	sister chromatid cohesion
W	0009986	cellular_component	cell surface
W	0016020	cellular_component	membrane
W	0016363	cellular_component	nuclear matrix
W	0016477	biological_process	cell migration
W	0030331	molecular_function	nuclear estrogen receptor binding
W	0030449	biological_process	regulation of complement activation
W	0032991	cellular_component	protein-containing complex
W	0033218	molecular_function	amide binding
W	0035632	cellular_component	mitochondrial prohibitin complex
W	0039529	biological_process	RIG-I signaling pathway
W	0042113	biological_process	B cell activation
W	0042802	molecular_function	identical protein binding
W	0042803	molecular_function	protein homodimerization activity
W	0043066	biological_process	negative regulation of apoptotic process
W	0043410	biological_process	positive regulation of MAPK cascade
W	0045892	biological_process	negative regulation of DNA-templated transcription
W	0046625	molecular_function	sphingolipid binding
W	0046982	molecular_function	protein heterodimerization activity
W	0050821	biological_process	protein stabilization
W	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
W	0071944	cellular_component	cell periphery
W	0098800	cellular_component	inner mitochondrial membrane protein complex
W	0140374	biological_process	antiviral innate immune response
W	1900208	biological_process	regulation of cardiolipin metabolic process
W	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
X	0000122	biological_process	negative regulation of transcription by RNA polymerase II
X	0001649	biological_process	osteoblast differentiation
X	0001850	molecular_function	complement component C3a binding
X	0001851	molecular_function	complement component C3b binding
X	0002639	biological_process	positive regulation of immunoglobulin production
X	0003714	molecular_function	transcription corepressor activity
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005737	cellular_component	cytoplasm
X	0005739	cellular_component	mitochondrion
X	0005743	cellular_component	mitochondrial inner membrane
X	0005769	cellular_component	early endosome
X	0005886	cellular_component	plasma membrane
X	0006355	biological_process	regulation of DNA-templated transcription
X	0007005	biological_process	mitochondrion organization
X	0007165	biological_process	signal transduction
X	0008285	biological_process	negative regulation of cell population proliferation
X	0009986	cellular_component	cell surface
X	0010628	biological_process	positive regulation of gene expression
X	0010944	biological_process	negative regulation of transcription by competitive promoter binding
X	0016020	cellular_component	membrane
X	0019899	molecular_function	enzyme binding
X	0030308	biological_process	negative regulation of cell growth
X	0031871	molecular_function	proteinase activated receptor binding
X	0032740	biological_process	positive regulation of interleukin-17 production
X	0035632	cellular_component	mitochondrial prohibitin complex
X	0039529	biological_process	RIG-I signaling pathway
X	0040029	biological_process	epigenetic regulation of gene expression
X	0042113	biological_process	B cell activation
X	0042177	biological_process	negative regulation of protein catabolic process
X	0042826	molecular_function	histone deacetylase binding
X	0042981	biological_process	regulation of apoptotic process
X	0043525	biological_process	positive regulation of neuron apoptotic process
X	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
X	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
X	0045892	biological_process	negative regulation of DNA-templated transcription
X	0045893	biological_process	positive regulation of DNA-templated transcription
X	0045917	biological_process	positive regulation of complement activation
X	0046718	biological_process	symbiont entry into host cell
X	0046982	molecular_function	protein heterodimerization activity
X	0048661	biological_process	positive regulation of smooth muscle cell proliferation
X	0050821	biological_process	protein stabilization
X	0050847	biological_process	progesterone receptor signaling pathway
X	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
X	0060766	biological_process	negative regulation of androgen receptor signaling pathway
X	0070062	cellular_component	extracellular exosome
X	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
X	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
X	0071354	biological_process	cellular response to interleukin-6
X	0071897	biological_process	DNA biosynthetic process
X	0072538	biological_process	T-helper 17 type immune response
X	0140374	biological_process	antiviral innate immune response
X	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
X	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	648
Details	Region: {"description":"Necessary for transcriptional repression","evidences":[{"source":"PubMed","id":"10359819","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	36
Details	Region: {"description":"LC3-interaction region","evidences":[{"source":"PubMed","id":"28017329","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	576
Details	Coiled coil: {"evidences":[{"source":"PubMed","id":"28017329","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6IQE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	12
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAR-2009","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Lilla S.","Zebisch A.","Kolch W."]}},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	12
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	48
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"O35129","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	12
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	408
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	12
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	12
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	24
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P67778","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	12
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P67778","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	12
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---