9O5S

minibinder-antigen complex BXMart1-3-MART1-HLA*A02

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000139	cellular_component	Golgi membrane
B	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
B	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
B	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
B	0002715	biological_process	regulation of natural killer cell mediated immunity
B	0002726	biological_process	positive regulation of T cell cytokine production
B	0005198	molecular_function	structural molecule activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005765	cellular_component	lysosomal membrane
B	0005783	cellular_component	endoplasmic reticulum
B	0005788	cellular_component	endoplasmic reticulum lumen
B	0005794	cellular_component	Golgi apparatus
B	0005886	cellular_component	plasma membrane
B	0005925	cellular_component	focal adhesion
B	0006879	biological_process	intracellular iron ion homeostasis
B	0006955	biological_process	immune response
B	0007608	biological_process	sensory perception of smell
B	0007611	biological_process	learning or memory
B	0009897	cellular_component	external side of plasma membrane
B	0009986	cellular_component	cell surface
B	0010038	biological_process	response to metal ion
B	0012507	cellular_component	ER to Golgi transport vesicle membrane
B	0016020	cellular_component	membrane
B	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
B	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
B	0023026	molecular_function	MHC class II protein complex binding
B	0030670	cellular_component	phagocytic vesicle membrane
B	0031901	cellular_component	early endosome membrane
B	0031902	cellular_component	late endosome membrane
B	0031905	cellular_component	early endosome lumen
B	0033572	biological_process	transferrin transport
B	0034756	biological_process	regulation of iron ion transport
B	0034757	biological_process	negative regulation of iron ion transport
B	0035580	cellular_component	specific granule lumen
B	0042605	molecular_function	peptide antigen binding
B	0042612	cellular_component	MHC class I protein complex
B	0042613	cellular_component	MHC class II protein complex
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0042824	cellular_component	MHC class I peptide loading complex
B	0048260	biological_process	positive regulation of receptor-mediated endocytosis
B	0048261	biological_process	negative regulation of receptor-mediated endocytosis
B	0050680	biological_process	negative regulation of epithelial cell proliferation
B	0050768	biological_process	negative regulation of neurogenesis
B	0050778	biological_process	positive regulation of immune response
B	0050870	biological_process	positive regulation of T cell activation
B	0051289	biological_process	protein homotetramerization
B	0055038	cellular_component	recycling endosome membrane
B	0070062	cellular_component	extracellular exosome
B	0071281	biological_process	cellular response to iron ion
B	0071316	biological_process	cellular response to nicotine
B	1904724	cellular_component	tertiary granule lumen
B	1990000	biological_process	amyloid fibril formation
B	1990712	cellular_component	HFE-transferrin receptor complex
B	2000774	biological_process	positive regulation of cellular senescence
B	2000978	biological_process	negative regulation of forebrain neuron differentiation
D	0000139	cellular_component	Golgi membrane
D	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
D	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
D	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
D	0002715	biological_process	regulation of natural killer cell mediated immunity
D	0002726	biological_process	positive regulation of T cell cytokine production
D	0005198	molecular_function	structural molecule activity
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005765	cellular_component	lysosomal membrane
D	0005783	cellular_component	endoplasmic reticulum
D	0005788	cellular_component	endoplasmic reticulum lumen
D	0005794	cellular_component	Golgi apparatus
D	0005886	cellular_component	plasma membrane
D	0005925	cellular_component	focal adhesion
D	0006879	biological_process	intracellular iron ion homeostasis
D	0006955	biological_process	immune response
D	0007608	biological_process	sensory perception of smell
D	0007611	biological_process	learning or memory
D	0009897	cellular_component	external side of plasma membrane
D	0009986	cellular_component	cell surface
D	0010038	biological_process	response to metal ion
D	0012507	cellular_component	ER to Golgi transport vesicle membrane
D	0016020	cellular_component	membrane
D	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
D	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
D	0023026	molecular_function	MHC class II protein complex binding
D	0030670	cellular_component	phagocytic vesicle membrane
D	0031901	cellular_component	early endosome membrane
D	0031902	cellular_component	late endosome membrane
D	0031905	cellular_component	early endosome lumen
D	0033572	biological_process	transferrin transport
D	0034756	biological_process	regulation of iron ion transport
D	0034757	biological_process	negative regulation of iron ion transport
D	0035580	cellular_component	specific granule lumen
D	0042605	molecular_function	peptide antigen binding
D	0042612	cellular_component	MHC class I protein complex
D	0042613	cellular_component	MHC class II protein complex
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0042824	cellular_component	MHC class I peptide loading complex
D	0048260	biological_process	positive regulation of receptor-mediated endocytosis
D	0048261	biological_process	negative regulation of receptor-mediated endocytosis
D	0050680	biological_process	negative regulation of epithelial cell proliferation
D	0050768	biological_process	negative regulation of neurogenesis
D	0050778	biological_process	positive regulation of immune response
D	0050870	biological_process	positive regulation of T cell activation
D	0051289	biological_process	protein homotetramerization
D	0055038	cellular_component	recycling endosome membrane
D	0070062	cellular_component	extracellular exosome
D	0071281	biological_process	cellular response to iron ion
D	0071316	biological_process	cellular response to nicotine
D	1904724	cellular_component	tertiary granule lumen
D	1990000	biological_process	amyloid fibril formation
D	1990712	cellular_component	HFE-transferrin receptor complex
D	2000774	biological_process	positive regulation of cellular senescence
D	2000978	biological_process	negative regulation of forebrain neuron differentiation
I	0000139	cellular_component	Golgi membrane
I	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
I	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
I	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
I	0002715	biological_process	regulation of natural killer cell mediated immunity
I	0002726	biological_process	positive regulation of T cell cytokine production
I	0005198	molecular_function	structural molecule activity
I	0005515	molecular_function	protein binding
I	0005576	cellular_component	extracellular region
I	0005765	cellular_component	lysosomal membrane
I	0005783	cellular_component	endoplasmic reticulum
I	0005788	cellular_component	endoplasmic reticulum lumen
I	0005794	cellular_component	Golgi apparatus
I	0005886	cellular_component	plasma membrane
I	0005925	cellular_component	focal adhesion
I	0006879	biological_process	intracellular iron ion homeostasis
I	0006955	biological_process	immune response
I	0007608	biological_process	sensory perception of smell
I	0007611	biological_process	learning or memory
I	0009897	cellular_component	external side of plasma membrane
I	0009986	cellular_component	cell surface
I	0010038	biological_process	response to metal ion
I	0012507	cellular_component	ER to Golgi transport vesicle membrane
I	0016020	cellular_component	membrane
I	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
I	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
I	0023026	molecular_function	MHC class II protein complex binding
I	0030670	cellular_component	phagocytic vesicle membrane
I	0031901	cellular_component	early endosome membrane
I	0031902	cellular_component	late endosome membrane
I	0031905	cellular_component	early endosome lumen
I	0033572	biological_process	transferrin transport
I	0034756	biological_process	regulation of iron ion transport
I	0034757	biological_process	negative regulation of iron ion transport
I	0035580	cellular_component	specific granule lumen
I	0042605	molecular_function	peptide antigen binding
I	0042612	cellular_component	MHC class I protein complex
I	0042613	cellular_component	MHC class II protein complex
I	0042802	molecular_function	identical protein binding
I	0042803	molecular_function	protein homodimerization activity
I	0042824	cellular_component	MHC class I peptide loading complex
I	0048260	biological_process	positive regulation of receptor-mediated endocytosis
I	0048261	biological_process	negative regulation of receptor-mediated endocytosis
I	0050680	biological_process	negative regulation of epithelial cell proliferation
I	0050768	biological_process	negative regulation of neurogenesis
I	0050778	biological_process	positive regulation of immune response
I	0050870	biological_process	positive regulation of T cell activation
I	0051289	biological_process	protein homotetramerization
I	0055038	cellular_component	recycling endosome membrane
I	0070062	cellular_component	extracellular exosome
I	0071281	biological_process	cellular response to iron ion
I	0071316	biological_process	cellular response to nicotine
I	1904724	cellular_component	tertiary granule lumen
I	1990000	biological_process	amyloid fibril formation
I	1990712	cellular_component	HFE-transferrin receptor complex
I	2000774	biological_process	positive regulation of cellular senescence
I	2000978	biological_process	negative regulation of forebrain neuron differentiation
M	0000139	cellular_component	Golgi membrane
M	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
M	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
M	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
M	0002715	biological_process	regulation of natural killer cell mediated immunity
M	0002726	biological_process	positive regulation of T cell cytokine production
M	0005198	molecular_function	structural molecule activity
M	0005515	molecular_function	protein binding
M	0005576	cellular_component	extracellular region
M	0005765	cellular_component	lysosomal membrane
M	0005783	cellular_component	endoplasmic reticulum
M	0005788	cellular_component	endoplasmic reticulum lumen
M	0005794	cellular_component	Golgi apparatus
M	0005886	cellular_component	plasma membrane
M	0005925	cellular_component	focal adhesion
M	0006879	biological_process	intracellular iron ion homeostasis
M	0006955	biological_process	immune response
M	0007608	biological_process	sensory perception of smell
M	0007611	biological_process	learning or memory
M	0009897	cellular_component	external side of plasma membrane
M	0009986	cellular_component	cell surface
M	0010038	biological_process	response to metal ion
M	0012507	cellular_component	ER to Golgi transport vesicle membrane
M	0016020	cellular_component	membrane
M	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
M	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
M	0023026	molecular_function	MHC class II protein complex binding
M	0030670	cellular_component	phagocytic vesicle membrane
M	0031901	cellular_component	early endosome membrane
M	0031902	cellular_component	late endosome membrane
M	0031905	cellular_component	early endosome lumen
M	0033572	biological_process	transferrin transport
M	0034756	biological_process	regulation of iron ion transport
M	0034757	biological_process	negative regulation of iron ion transport
M	0035580	cellular_component	specific granule lumen
M	0042605	molecular_function	peptide antigen binding
M	0042612	cellular_component	MHC class I protein complex
M	0042613	cellular_component	MHC class II protein complex
M	0042802	molecular_function	identical protein binding
M	0042803	molecular_function	protein homodimerization activity
M	0042824	cellular_component	MHC class I peptide loading complex
M	0048260	biological_process	positive regulation of receptor-mediated endocytosis
M	0048261	biological_process	negative regulation of receptor-mediated endocytosis
M	0050680	biological_process	negative regulation of epithelial cell proliferation
M	0050768	biological_process	negative regulation of neurogenesis
M	0050778	biological_process	positive regulation of immune response
M	0050870	biological_process	positive regulation of T cell activation
M	0051289	biological_process	protein homotetramerization
M	0055038	cellular_component	recycling endosome membrane
M	0070062	cellular_component	extracellular exosome
M	0071281	biological_process	cellular response to iron ion
M	0071316	biological_process	cellular response to nicotine
M	1904724	cellular_component	tertiary granule lumen
M	1990000	biological_process	amyloid fibril formation
M	1990712	cellular_component	HFE-transferrin receptor complex
M	2000774	biological_process	positive regulation of cellular senescence
M	2000978	biological_process	negative regulation of forebrain neuron differentiation

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH

Chain	Residue	Details
B	TYR78-HIS84
A	TYR257-HIS263

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	352
Details	Domain: {"description":"Ig-like C1-type"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"Pyrrolidone carboxylic acid; in form pI 5.3","evidences":[{"source":"PubMed","id":"7554280","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis","evidences":[{"source":"PubMed","id":"7918443","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	24
Details	Glycosylation: {"description":"N-linked (Glc) (glycation) lysine; in vitro","evidences":[{"source":"PubMed","id":"7918443","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---