9NUC

CryoEM analysis of Phosphoglucose isomerase from P. aeruginosa reveals potential clinically relevant features

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004347	molecular_function	glucose-6-phosphate isomerase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006094	biological_process	gluconeogenesis
A	0006096	biological_process	glycolytic process
A	0048029	molecular_function	monosaccharide binding
A	0051156	biological_process	glucose 6-phosphate metabolic process
B	0004347	molecular_function	glucose-6-phosphate isomerase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006094	biological_process	gluconeogenesis
B	0006096	biological_process	glycolytic process
B	0048029	molecular_function	monosaccharide binding
B	0051156	biological_process	glucose 6-phosphate metabolic process
C	0004347	molecular_function	glucose-6-phosphate isomerase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006094	biological_process	gluconeogenesis
C	0006096	biological_process	glycolytic process
C	0048029	molecular_function	monosaccharide binding
C	0051156	biological_process	glucose 6-phosphate metabolic process
D	0004347	molecular_function	glucose-6-phosphate isomerase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006094	biological_process	gluconeogenesis
D	0006096	biological_process	glycolytic process
D	0048029	molecular_function	monosaccharide binding
D	0051156	biological_process	glucose 6-phosphate metabolic process
E	0004347	molecular_function	glucose-6-phosphate isomerase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006094	biological_process	gluconeogenesis
E	0006096	biological_process	glycolytic process
E	0048029	molecular_function	monosaccharide binding
E	0051156	biological_process	glucose 6-phosphate metabolic process
F	0004347	molecular_function	glucose-6-phosphate isomerase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006094	biological_process	gluconeogenesis
F	0006096	biological_process	glycolytic process
F	0048029	molecular_function	monosaccharide binding
F	0051156	biological_process	glucose 6-phosphate metabolic process
G	0004347	molecular_function	glucose-6-phosphate isomerase activity
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006094	biological_process	gluconeogenesis
G	0006096	biological_process	glycolytic process
G	0048029	molecular_function	monosaccharide binding
G	0051156	biological_process	glucose 6-phosphate metabolic process
H	0004347	molecular_function	glucose-6-phosphate isomerase activity
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006094	biological_process	gluconeogenesis
H	0006096	biological_process	glycolytic process
H	0048029	molecular_function	monosaccharide binding
H	0051156	biological_process	glucose 6-phosphate metabolic process
I	0004347	molecular_function	glucose-6-phosphate isomerase activity
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006094	biological_process	gluconeogenesis
I	0006096	biological_process	glycolytic process
I	0048029	molecular_function	monosaccharide binding
I	0051156	biological_process	glucose 6-phosphate metabolic process
J	0004347	molecular_function	glucose-6-phosphate isomerase activity
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006094	biological_process	gluconeogenesis
J	0006096	biological_process	glycolytic process
J	0048029	molecular_function	monosaccharide binding
J	0051156	biological_process	glucose 6-phosphate metabolic process

Functional Information from PROSITE/UniProt

site_id	PS00174
Number of Residues	18
Details	P_GLUCOSE_ISOMERASE_2 Phosphoglucose isomerase signature 2. SiLWginaFDQwGVElgK

Chain	Residue	Details
A	SER501-LYS518

---

site_id	PS00765
Number of Residues	14
Details	P_GLUCOSE_ISOMERASE_1 Phosphoglucose isomerase signature 1. DwVGGRYSLwSAIG

Chain	Residue	Details
A	ASP269-GLY282

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00473","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	20
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00473","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---