9NQJ

Cryo-EM structure of a bacterial prototype ATP-binding cassette transporter MalFGK2.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0015423	molecular_function	ABC-type maltose transporter activity
A	0015768	biological_process	maltose transport
A	0016020	cellular_component	membrane
A	0034763	biological_process	negative regulation of transmembrane transport
A	0042956	biological_process	maltodextrin transmembrane transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0140297	molecular_function	DNA-binding transcription factor binding
A	0140359	molecular_function	ABC-type transporter activity
A	1902344	biological_process	negative regulation of maltose transport
A	1904981	biological_process	maltose transmembrane transport
A	1990060	cellular_component	maltose transport complex
A	1990154	cellular_component	enzyme IIA-maltose transporter complex
B	0000166	molecular_function	nucleotide binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0015423	molecular_function	ABC-type maltose transporter activity
B	0015768	biological_process	maltose transport
B	0016020	cellular_component	membrane
B	0034763	biological_process	negative regulation of transmembrane transport
B	0042956	biological_process	maltodextrin transmembrane transport
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0140297	molecular_function	DNA-binding transcription factor binding
B	0140359	molecular_function	ABC-type transporter activity
B	1902344	biological_process	negative regulation of maltose transport
B	1904981	biological_process	maltose transmembrane transport
B	1990060	cellular_component	maltose transport complex
B	1990154	cellular_component	enzyme IIA-maltose transporter complex
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0006974	biological_process	DNA damage response
F	0015423	molecular_function	ABC-type maltose transporter activity
F	0015768	biological_process	maltose transport
F	0016020	cellular_component	membrane
F	0034763	biological_process	negative regulation of transmembrane transport
F	0042956	biological_process	maltodextrin transmembrane transport
F	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
F	1902344	biological_process	negative regulation of maltose transport
F	1904981	biological_process	maltose transmembrane transport
F	1990060	cellular_component	maltose transport complex
F	1990154	cellular_component	enzyme IIA-maltose transporter complex
G	0005515	molecular_function	protein binding
G	0005886	cellular_component	plasma membrane
G	0015423	molecular_function	ABC-type maltose transporter activity
G	0015768	biological_process	maltose transport
G	0016020	cellular_component	membrane
G	0034763	biological_process	negative regulation of transmembrane transport
G	0042956	biological_process	maltodextrin transmembrane transport
G	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
G	1902344	biological_process	negative regulation of maltose transport
G	1904981	biological_process	maltose transmembrane transport
G	1990060	cellular_component	maltose transport complex
G	1990154	cellular_component	enzyme IIA-maltose transporter complex

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQRQRVAIGRTL

Chain	Residue	Details
A	LEU134-LEU148

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	460
Details	Domain: {"description":"ABC transporter","evidences":[{"source":"HAMAP-Rule","id":"MF_01709","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01709","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	70
Details	Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	258
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	117
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	196
Details	Domain: {"description":"ABC transmembrane type-1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00441","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---