9NNP
Composite structure of HSV-1 helicase-primase in complex with a forked DNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006260 | biological_process | DNA replication |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0039686 | biological_process | bidirectional double-stranded viral DNA replication |
| A | 0042025 | cellular_component | host cell nucleus |
| B | 0006260 | biological_process | DNA replication |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016740 | molecular_function | transferase activity |
| B | 0039686 | biological_process | bidirectional double-stranded viral DNA replication |
| B | 0042025 | cellular_component | host cell nucleus |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0006260 | biological_process | DNA replication |
| C | 0039686 | biological_process | bidirectional double-stranded viral DNA replication |
| C | 0042025 | cellular_component | host cell nucleus |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04030","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Zinc finger: {"description":"CHC2-type","evidences":[{"source":"HAMAP-Rule","id":"MF_04011","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8189507","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Essential for primase activity","evidences":[{"source":"HAMAP-Rule","id":"MF_04011","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
