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9NNJ

Crystal structure of CYP46A1 with 3-chloro-N-[(3M)-3-(1,3-oxazol-5-yl)phenyl]-N-(propan-2-yl)benzene-1-sulfonamide (compound 2)

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0004497molecular_functionmonooxygenase activity
A0005783cellular_componentendoplasmic reticulum
A0005789cellular_componentendoplasmic reticulum membrane
A0006629biological_processlipid metabolic process
A0006699biological_processbile acid biosynthetic process
A0006707biological_processcholesterol catabolic process
A0006805biological_processxenobiotic metabolic process
A0007399biological_processnervous system development
A0008202biological_processsteroid metabolic process
A0008203biological_processcholesterol metabolic process
A0008207biological_processC21-steroid hormone metabolic process
A0008395molecular_functionsteroid hydroxylase activity
A0016020cellular_componentmembrane
A0016125biological_processsterol metabolic process
A0016491molecular_functionoxidoreductase activity
A0020037molecular_functionheme binding
A0030425cellular_componentdendrite
A0033781molecular_functioncholesterol 24-hydroxylase activity
A0042448biological_processprogesterone metabolic process
A0042995cellular_componentcell projection
A0045202cellular_componentsynapse
A0046872molecular_functionmetal ion binding
A0050649molecular_functiontestosterone 6-beta-hydroxylase activity
A0062184molecular_functiontestosterone 16-beta-hydroxylase activity
A0065008biological_processregulation of biological quality
A0098793cellular_componentpresynapse
A0098794cellular_componentpostsynapse
A1900271biological_processregulation of long-term synaptic potentiation
A1903044biological_processprotein localization to membrane raft
Functional Information from PROSITE/UniProt
site_idPS00086
Number of Residues10
DetailsCYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FSlGHRSCIG
ChainResidueDetails
APHE430-GLY439

Functional Information from SwissProt/UniProt

236620

PDB entries from 2025-05-28

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