Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9NAV

CryoEM structure of human astrovirus 1 spike in complex with human neonatal Fc receptor

Functional Information from GO Data
ChainGOidnamespacecontents
H0000139cellular_componentGolgi membrane
H0002477biological_processantigen processing and presentation of exogenous peptide antigen via MHC class Ib
H0002502biological_processpeptide antigen assembly with MHC class I protein complex
H0002503biological_processpeptide antigen assembly with MHC class II protein complex
H0002715biological_processregulation of natural killer cell mediated immunity
H0002726biological_processpositive regulation of T cell cytokine production
H0005198molecular_functionstructural molecule activity
H0005515molecular_functionprotein binding
H0005576cellular_componentextracellular region
H0005765cellular_componentlysosomal membrane
H0005783cellular_componentendoplasmic reticulum
H0005788cellular_componentendoplasmic reticulum lumen
H0005794cellular_componentGolgi apparatus
H0005886cellular_componentplasma membrane
H0005925cellular_componentfocal adhesion
H0006879biological_processintracellular iron ion homeostasis
H0007608biological_processsensory perception of smell
H0007611biological_processlearning or memory
H0009897cellular_componentexternal side of plasma membrane
H0009986cellular_componentcell surface
H0010038biological_processresponse to metal ion
H0012507cellular_componentER to Golgi transport vesicle membrane
H0016020cellular_componentmembrane
H0019885biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I
H0019886biological_processantigen processing and presentation of exogenous peptide antigen via MHC class II
H0023026molecular_functionMHC class II protein complex binding
H0030670cellular_componentphagocytic vesicle membrane
H0031901cellular_componentearly endosome membrane
H0031902cellular_componentlate endosome membrane
H0031905cellular_componentearly endosome lumen
H0032398cellular_componentMHC class Ib protein complex
H0033572biological_processtransferrin transport
H0034756biological_processregulation of iron ion transport
H0034757biological_processnegative regulation of iron ion transport
H0035580cellular_componentspecific granule lumen
H0042605molecular_functionpeptide antigen binding
H0042612cellular_componentMHC class I protein complex
H0042613cellular_componentMHC class II protein complex
H0042802molecular_functionidentical protein binding
H0042803molecular_functionprotein homodimerization activity
H0042824cellular_componentMHC class I peptide loading complex
H0048260biological_processpositive regulation of receptor-mediated endocytosis
H0048261biological_processnegative regulation of receptor-mediated endocytosis
H0050680biological_processnegative regulation of epithelial cell proliferation
H0050768biological_processnegative regulation of neurogenesis
H0050778biological_processpositive regulation of immune response
H0050870biological_processpositive regulation of T cell activation
H0051289biological_processprotein homotetramerization
H0055038cellular_componentrecycling endosome membrane
H0070062cellular_componentextracellular exosome
H0071281biological_processcellular response to iron ion
H0071316biological_processcellular response to nicotine
H1904724cellular_componenttertiary granule lumen
H1990000biological_processamyloid fibril formation
H1990712cellular_componentHFE-transferrin receptor complex
H2000774biological_processpositive regulation of cellular senescence
H2000978biological_processnegative regulation of forebrain neuron differentiation
J0000139cellular_componentGolgi membrane
J0002477biological_processantigen processing and presentation of exogenous peptide antigen via MHC class Ib
J0002502biological_processpeptide antigen assembly with MHC class I protein complex
J0002503biological_processpeptide antigen assembly with MHC class II protein complex
J0002715biological_processregulation of natural killer cell mediated immunity
J0002726biological_processpositive regulation of T cell cytokine production
J0005198molecular_functionstructural molecule activity
J0005515molecular_functionprotein binding
J0005576cellular_componentextracellular region
J0005765cellular_componentlysosomal membrane
J0005783cellular_componentendoplasmic reticulum
J0005788cellular_componentendoplasmic reticulum lumen
J0005794cellular_componentGolgi apparatus
J0005886cellular_componentplasma membrane
J0005925cellular_componentfocal adhesion
J0006879biological_processintracellular iron ion homeostasis
J0007608biological_processsensory perception of smell
J0007611biological_processlearning or memory
J0009897cellular_componentexternal side of plasma membrane
J0009986cellular_componentcell surface
J0010038biological_processresponse to metal ion
J0012507cellular_componentER to Golgi transport vesicle membrane
J0016020cellular_componentmembrane
J0019885biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I
J0019886biological_processantigen processing and presentation of exogenous peptide antigen via MHC class II
J0023026molecular_functionMHC class II protein complex binding
J0030670cellular_componentphagocytic vesicle membrane
J0031901cellular_componentearly endosome membrane
J0031902cellular_componentlate endosome membrane
J0031905cellular_componentearly endosome lumen
J0032398cellular_componentMHC class Ib protein complex
J0033572biological_processtransferrin transport
J0034756biological_processregulation of iron ion transport
J0034757biological_processnegative regulation of iron ion transport
J0035580cellular_componentspecific granule lumen
J0042605molecular_functionpeptide antigen binding
J0042612cellular_componentMHC class I protein complex
J0042613cellular_componentMHC class II protein complex
J0042802molecular_functionidentical protein binding
J0042803molecular_functionprotein homodimerization activity
J0042824cellular_componentMHC class I peptide loading complex
J0048260biological_processpositive regulation of receptor-mediated endocytosis
J0048261biological_processnegative regulation of receptor-mediated endocytosis
J0050680biological_processnegative regulation of epithelial cell proliferation
J0050768biological_processnegative regulation of neurogenesis
J0050778biological_processpositive regulation of immune response
J0050870biological_processpositive regulation of T cell activation
J0051289biological_processprotein homotetramerization
J0055038cellular_componentrecycling endosome membrane
J0070062cellular_componentextracellular exosome
J0071281biological_processcellular response to iron ion
J0071316biological_processcellular response to nicotine
J1904724cellular_componenttertiary granule lumen
J1990000biological_processamyloid fibril formation
J1990712cellular_componentHFE-transferrin receptor complex
J2000774biological_processpositive regulation of cellular senescence
J2000978biological_processnegative regulation of forebrain neuron differentiation
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YCCIVQH
ChainResidueDetails
GTYR250-HIS256
HTYR78-HIS84
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues174
DetailsDomain: {"description":"Ig-like C1-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues172
DetailsRegion: {"description":"Alpha-1","evidences":[{"source":"PubMed","id":"10933786","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1EXU","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues178
DetailsRegion: {"description":"Alpha-2","evidences":[{"source":"PubMed","id":"10933786","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1EXU","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues178
DetailsRegion: {"description":"Alpha-3","evidences":[{"source":"PubMed","id":"10933786","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1EXU","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues176
DetailsDomain: {"description":"Ig-like C1-type"}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues2
DetailsModified residue: {"description":"Pyrrolidone carboxylic acid; in form pI 5.3","evidences":[{"source":"PubMed","id":"7554280","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis","evidences":[{"source":"PubMed","id":"7918443","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues12
DetailsGlycosylation: {"description":"N-linked (Glc) (glycation) lysine; in vitro","evidences":[{"source":"PubMed","id":"7918443","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues768
DetailsRegion: {"description":"Inner core","evidences":[{"source":"UniProtKB","id":"Q9IFX1","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

255900

PDB entries from 2026-07-01

PDB statisticsPDBj update infoContact PDBjnumon