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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9MU9

Structure of a native Drosophila melanogaster Nucleosome Elongation Complex (Pol II EC-nucleosome). Composite map

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003899molecular_functionDNA-directed RNA polymerase activity
A0006351biological_processDNA-templated transcription
B0000428cellular_componentDNA-directed RNA polymerase complex
B0003677molecular_functionDNA binding
B0003899molecular_functionDNA-directed RNA polymerase activity
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005665cellular_componentRNA polymerase II, core complex
B0006351biological_processDNA-templated transcription
B0006354biological_processDNA-templated transcription elongation
B0006366biological_processtranscription by RNA polymerase II
B0006367biological_processtranscription initiation at RNA polymerase II promoter
B0008270molecular_functionzinc ion binding
B0016740molecular_functiontransferase activity
B0016779molecular_functionnucleotidyltransferase activity
B0032549molecular_functionribonucleoside binding
B0034062molecular_function5'-3' RNA polymerase activity
B0046872molecular_functionmetal ion binding
C0000428cellular_componentDNA-directed RNA polymerase complex
C0003677molecular_functionDNA binding
C0003899molecular_functionDNA-directed RNA polymerase activity
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005665cellular_componentRNA polymerase II, core complex
C0005700cellular_componentpolytene chromosome
C0005703cellular_componentpolytene chromosome puff
C0005737cellular_componentcytoplasm
C0006351biological_processDNA-templated transcription
C0006366biological_processtranscription by RNA polymerase II
C0006367biological_processtranscription initiation at RNA polymerase II promoter
C0016740molecular_functiontransferase activity
C0016779molecular_functionnucleotidyltransferase activity
C0034605biological_processcellular response to heat
C0046872molecular_functionmetal ion binding
C0046983molecular_functionprotein dimerization activity
E0000428cellular_componentDNA-directed RNA polymerase complex
E0003677molecular_functionDNA binding
E0003899molecular_functionDNA-directed RNA polymerase activity
E0005634cellular_componentnucleus
E0005654cellular_componentnucleoplasm
E0005665cellular_componentRNA polymerase II, core complex
E0005666cellular_componentRNA polymerase III complex
E0005736cellular_componentRNA polymerase I complex
E0006351biological_processDNA-templated transcription
E0006360biological_processtranscription by RNA polymerase I
E0006361biological_processtranscription initiation at RNA polymerase I promoter
E0006362biological_processtranscription elongation by RNA polymerase I
E0006366biological_processtranscription by RNA polymerase II
E0006367biological_processtranscription initiation at RNA polymerase II promoter
E0006383biological_processtranscription by RNA polymerase III
E0006384biological_processtranscription initiation at RNA polymerase III promoter
E0006386biological_processtermination of RNA polymerase III transcription
E0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
E0042797biological_processtRNA transcription by RNA polymerase III
F0003677molecular_functionDNA binding
F0003899molecular_functionDNA-directed RNA polymerase activity
F0005634cellular_componentnucleus
F0005665cellular_componentRNA polymerase II, core complex
F0006351biological_processDNA-templated transcription
H0000428cellular_componentDNA-directed RNA polymerase complex
H0003899molecular_functionDNA-directed RNA polymerase activity
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005665cellular_componentRNA polymerase II, core complex
H0005666cellular_componentRNA polymerase III complex
H0005736cellular_componentRNA polymerase I complex
H0006351biological_processDNA-templated transcription
H0006360biological_processtranscription by RNA polymerase I
H0006361biological_processtranscription initiation at RNA polymerase I promoter
H0006362biological_processtranscription elongation by RNA polymerase I
H0006366biological_processtranscription by RNA polymerase II
H0006367biological_processtranscription initiation at RNA polymerase II promoter
H0006383biological_processtranscription by RNA polymerase III
H0006384biological_processtranscription initiation at RNA polymerase III promoter
H0006386biological_processtermination of RNA polymerase III transcription
H0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
H0042797biological_processtRNA transcription by RNA polymerase III
I0000278biological_processmitotic cell cycle
I0000428cellular_componentDNA-directed RNA polymerase complex
I0001193biological_processmaintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
I0003676molecular_functionnucleic acid binding
I0003899molecular_functionDNA-directed RNA polymerase activity
I0005634cellular_componentnucleus
I0005654cellular_componentnucleoplasm
I0005665cellular_componentRNA polymerase II, core complex
I0005730cellular_componentnucleolus
I0006283biological_processtranscription-coupled nucleotide-excision repair
I0006351biological_processDNA-templated transcription
I0006366biological_processtranscription by RNA polymerase II
I0006367biological_processtranscription initiation at RNA polymerase II promoter
I0008270molecular_functionzinc ion binding
I0046872molecular_functionmetal ion binding
J0000428cellular_componentDNA-directed RNA polymerase complex
J0003677molecular_functionDNA binding
J0003899molecular_functionDNA-directed RNA polymerase activity
J0005634cellular_componentnucleus
J0005665cellular_componentRNA polymerase II, core complex
J0005666cellular_componentRNA polymerase III complex
J0005736cellular_componentRNA polymerase I complex
J0006351biological_processDNA-templated transcription
J0006360biological_processtranscription by RNA polymerase I
J0006361biological_processtranscription initiation at RNA polymerase I promoter
J0006362biological_processtranscription elongation by RNA polymerase I
J0006366biological_processtranscription by RNA polymerase II
J0006367biological_processtranscription initiation at RNA polymerase II promoter
J0006383biological_processtranscription by RNA polymerase III
J0006384biological_processtranscription initiation at RNA polymerase III promoter
J0006386biological_processtermination of RNA polymerase III transcription
J0008270molecular_functionzinc ion binding
J0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
J0042797biological_processtRNA transcription by RNA polymerase III
J0046872molecular_functionmetal ion binding
K0000428cellular_componentDNA-directed RNA polymerase complex
K0003677molecular_functionDNA binding
K0003899molecular_functionDNA-directed RNA polymerase activity
K0005515molecular_functionprotein binding
K0005634cellular_componentnucleus
K0005665cellular_componentRNA polymerase II, core complex
K0006351biological_processDNA-templated transcription
K0006366biological_processtranscription by RNA polymerase II
K0006367biological_processtranscription initiation at RNA polymerase II promoter
K0046983molecular_functionprotein dimerization activity
L0003677molecular_functionDNA binding
L0003899molecular_functionDNA-directed RNA polymerase activity
L0006351biological_processDNA-templated transcription
L0008270molecular_functionzinc ion binding
a0000786cellular_componentnucleosome
a0003677molecular_functionDNA binding
a0030527molecular_functionstructural constituent of chromatin
a0046982molecular_functionprotein heterodimerization activity
b0003677molecular_functionDNA binding
b0030527molecular_functionstructural constituent of chromatin
b0046982molecular_functionprotein heterodimerization activity
c0000786cellular_componentnucleosome
c0003677molecular_functionDNA binding
c0030527molecular_functionstructural constituent of chromatin
c0046982molecular_functionprotein heterodimerization activity
d0000786cellular_componentnucleosome
d0003677molecular_functionDNA binding
d0030527molecular_functionstructural constituent of chromatin
d0046982molecular_functionprotein heterodimerization activity
e0000786cellular_componentnucleosome
e0003677molecular_functionDNA binding
e0030527molecular_functionstructural constituent of chromatin
e0046982molecular_functionprotein heterodimerization activity
f0003677molecular_functionDNA binding
f0030527molecular_functionstructural constituent of chromatin
f0046982molecular_functionprotein heterodimerization activity
g0000786cellular_componentnucleosome
g0003677molecular_functionDNA binding
g0030527molecular_functionstructural constituent of chromatin
g0046982molecular_functionprotein heterodimerization activity
h0000786cellular_componentnucleosome
h0003677molecular_functionDNA binding
h0030527molecular_functionstructural constituent of chromatin
h0046982molecular_functionprotein heterodimerization activity
Functional Information from PROSITE/UniProt
site_idPS00046
Number of Residues7
DetailsHISTONE_H2A Histone H2A signature. AGLqFPV
ChainResidueDetails
gALA21-VAL27
site_idPS00357
Number of Residues23
DetailsHISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG
ChainResidueDetails
hARG90-GLY112
site_idPS00446
Number of Residues41
DetailsRNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSLRRvfiaetptlAidwVqleaNsTvlsDEfLAhRIGLIP
ChainResidueDetails
CASN32-PRO72
site_idPS00466
Number of Residues38
DetailsZF_TFIIS_1 Zinc finger TFIIS-type signature. CpkCshreavffqAQTRRaEEEmrlyyvCtnqn.CthrW
ChainResidueDetails
ICYS90-TRP127
site_idPS00959
Number of Residues9
DetailsHISTONE_H3_2 Histone H3 signature 2. PFqRLVREI
ChainResidueDetails
ePRO67-ILE75
site_idPS01030
Number of Residues27
DetailsRNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCQECNNMLypkedkenkillyaCrnC
ChainResidueDetails
IPHE20-CYS46
site_idPS01110
Number of Residues14
DetailsRNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPEHvvMtvEE
ChainResidueDetails
EHIS142-GLU155
site_idPS01111
Number of Residues15
DetailsRNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARvLGtRAlQ
ChainResidueDetails
FTHR61-GLN75
site_idPS01112
Number of Residues10
DetailsRNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IIPIrCFTCG
ChainResidueDetails
JILE2-GLY11
site_idPS01154
Number of Residues32
DetailsRNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. InkEdHTLgNmIrnqLlkdpnVlfagYkvpHP
ChainResidueDetails
KILE35-PRO66
site_idPS01166
Number of Residues13
DetailsRNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT
ChainResidueDetails
BGLY934-THR946
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues18
DetailsModified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"22389435","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues2
DetailsModified residue: {"description":"N5-methylglutamine","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues2
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"15386022","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues2
DetailsGlycosylation: {"description":"O-linked (GlcNAc) serine","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues4
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"21764853","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18188155","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues2
DetailsModified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"22389435","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues2
DetailsModified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"14732680","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues4
DetailsModified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18327897","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues22
DetailsRegion: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues12
DetailsRegion: {"description":"Bridging helix"}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues11
DetailsBinding site: {"evidences":[{"source":"UniProtKB","id":"P04050","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues2
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P04050","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI13
Number of Residues21
DetailsZinc finger: {"description":"C4-type"}
ChainResidueDetails
site_idSWS_FT_FI14
Number of Residues9
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI16
Number of Residues25
DetailsZinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI17
Number of Residues42
DetailsZinc finger: {"description":"TFIIS-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00472","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI18
Number of Residues4
DetailsBinding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10145","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI19
Number of Residues4
DetailsBinding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00472","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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