9MQZ

Structure of mycobacterial NDH2 (type II NADH:quinone oxidoreductase) with 2-mercapto-quinazolinone inhibitor.

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003954	molecular_function	NADH dehydrogenase activity
A	0003955	molecular_function	NAD(P)H dehydrogenase (quinone) activity
A	0005886	cellular_component	plasma membrane
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0019646	biological_process	aerobic electron transport chain
A	0050136	molecular_function	NADH dehydrogenase (quinone) (non-electrogenic) activity
B	0003954	molecular_function	NADH dehydrogenase activity
B	0003955	molecular_function	NAD(P)H dehydrogenase (quinone) activity
B	0005886	cellular_component	plasma membrane
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0019646	biological_process	aerobic electron transport chain
B	0050136	molecular_function	NADH dehydrogenase (quinone) (non-electrogenic) activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	PHE384-PHE404
B	PHE384-PHE404

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:Q2FZV7

Chain	Residue	Details
A	GLU181
B	GLU181

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q2FZV7

Chain	Residue	Details
A	GLY18
A	VAL86
A	ASP319
A	ALA330
B	GLY18
B	VAL86
B	ASP319
B	ALA330

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