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9MNA

Structure of the human mitochondrial promoter-initiated transcription elongation complex with TEFM, pEC9-TEFM

Functional Information from GO Data
ChainGOidnamespacecontents
A0002082biological_processregulation of oxidative phosphorylation
A0003711molecular_functiontranscription elongation factor activity
A0003723molecular_functionRNA binding
A0005515molecular_functionprotein binding
A0005739cellular_componentmitochondrion
A0005759cellular_componentmitochondrial matrix
A0006264biological_processmitochondrial DNA replication
A0006351biological_processDNA-templated transcription
A0008821molecular_functioncrossover junction DNA endonuclease activity
A0042645cellular_componentmitochondrial nucleoid
A1903109biological_processpositive regulation of mitochondrial transcription
A1990904cellular_componentribonucleoprotein complex
B0002082biological_processregulation of oxidative phosphorylation
B0003711molecular_functiontranscription elongation factor activity
B0003723molecular_functionRNA binding
B0005515molecular_functionprotein binding
B0005739cellular_componentmitochondrion
B0005759cellular_componentmitochondrial matrix
B0006264biological_processmitochondrial DNA replication
B0006351biological_processDNA-templated transcription
B0008821molecular_functioncrossover junction DNA endonuclease activity
B0042645cellular_componentmitochondrial nucleoid
B1903109biological_processpositive regulation of mitochondrial transcription
B1990904cellular_componentribonucleoprotein complex
E0000175molecular_function3'-5'-RNA exonuclease activity
E0000428cellular_componentDNA-directed RNA polymerase complex
E0001018molecular_functionmitochondrial promoter sequence-specific DNA binding
E0003723molecular_functionRNA binding
E0003899molecular_functionDNA-directed RNA polymerase activity
E0005515molecular_functionprotein binding
E0005739cellular_componentmitochondrion
E0005759cellular_componentmitochondrial matrix
E0006264biological_processmitochondrial DNA replication
E0006390biological_processmitochondrial transcription
E0006391biological_processtranscription initiation at mitochondrial promoter
E0016740molecular_functiontransferase activity
E0016779molecular_functionnucleotidyltransferase activity
E0032991cellular_componentprotein-containing complex
E0034062molecular_function5'-3' RNA polymerase activity
E0034245cellular_componentmitochondrial DNA-directed RNA polymerase complex
E0042645cellular_componentmitochondrial nucleoid
E0043565molecular_functionsequence-specific DNA binding
Functional Information from PROSITE/UniProt
site_idPS00489
Number of Residues15
DetailsRNA_POL_PHAGE_2 Bacteriophage-type RNA polymerase family active site signature 2. ItRkvvKqtVMTvvY
ChainResidueDetails
EILE985-TYR999

site_idPS00900
Number of Residues12
DetailsRNA_POL_PHAGE_1 Bacteriophage-type RNA polymerase family active site signature 1. PVhqDGSCNGLQ
ChainResidueDetails
EPRO918-GLN929

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsActive site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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