9MC2
Cryo-EM structure of dopaminated Tau fibril
Functional Information from PROSITE/UniProt
| site_id | PS00229 |
| Number of Residues | 13 |
| Details | TAU_MAP_1 Tau and MAP proteins tubulin-binding repeat signature. GSteNlkHqPGGG |
| Chain | Residue | Details |
| A | GLY230-GLY242 | |
| A | GLY261-GLY273 | |
| A | GLY323-GLY335 | |
| A | GLY355-GLY367 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Site: {"description":"Not glycated","evidences":[{"source":"PubMed","id":"9326300","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphoserine; by PHK","evidences":[{"source":"PubMed","id":"7706316","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8999860","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P10637","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); in PHF-tau","evidences":[{"source":"PubMed","id":"16443603","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
