Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9LSI

Cryo-EM structure of the S82C-S82C diabody complex (CitS-diabody #2-TLR3)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006101	biological_process	citrate metabolic process
A	0006811	biological_process	monoatomic ion transport
A	0006814	biological_process	sodium ion transport
A	0015293	molecular_function	symporter activity
A	0046872	molecular_function	metal ion binding
A	0055085	biological_process	transmembrane transport
B	0005886	cellular_component	plasma membrane
B	0006101	biological_process	citrate metabolic process
B	0006811	biological_process	monoatomic ion transport
B	0006814	biological_process	sodium ion transport
B	0015293	molecular_function	symporter activity
B	0046872	molecular_function	metal ion binding
B	0055085	biological_process	transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Transmembrane: {"description":"Helical; Name=TM 1","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	84
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=TM 2","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	48
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	28
Details	Transmembrane: {"description":"Helical; Name=TM 3","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	28
Details	Transmembrane: {"description":"Helical; Name=TM 4","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	58
Details	Transmembrane: {"description":"Helical; Name=TM 5","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	72
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"10825453","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	14
Details	Intramembrane: {"description":"Helical; Name=TM 6 (HP1)","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=TM 7","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	44
Details	Transmembrane: {"description":"Helical; Name=TM 8","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	30
Details	Transmembrane: {"description":"Helical; Name=TM 9","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	46
Details	Transmembrane: {"description":"Helical; Name=TM 10","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	42
Details	Transmembrane: {"description":"Helical; Name=TM 11","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	80
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"10825453","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	14
Details	Intramembrane: {"description":"Helical; Name=TM 12 (HP2)","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	42
Details	Transmembrane: {"description":"Helical; Name=TM 13","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	14
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8810332","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XAT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI20
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5X9R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XAT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI21
Number of Residues	21
Details	Repeat: {"description":"LRR 1"}

Chain

Residue

Details

site_id	SWS_FT_FI22
Number of Residues	21
Details	Repeat: {"description":"LRR 2"}

Chain

Residue

Details

site_id	SWS_FT_FI23
Number of Residues	21
Details	Repeat: {"description":"LRR 3"}

Chain

Residue

Details

site_id	SWS_FT_FI24
Number of Residues	21
Details	Repeat: {"description":"LRR 4"}

Chain

Residue

Details

site_id	SWS_FT_FI25
Number of Residues	20
Details	Repeat: {"description":"LRR 5"}

Chain

Residue

Details

site_id	SWS_FT_FI26
Number of Residues	21
Details	Repeat: {"description":"LRR 6"}

Chain

Residue

Details

site_id	SWS_FT_FI27
Number of Residues	21
Details	Repeat: {"description":"LRR 7"}

Chain

Residue

Details

site_id	SWS_FT_FI28
Number of Residues	22
Details	Repeat: {"description":"LRR 8"}

Chain

Residue

Details

site_id	SWS_FT_FI29
Number of Residues	21
Details	Repeat: {"description":"LRR 9"}

Chain

Residue

Details

site_id	SWS_FT_FI30
Number of Residues	21
Details	Repeat: {"description":"LRR 10"}

Chain

Residue

Details

site_id	SWS_FT_FI31
Number of Residues	21
Details	Repeat: {"description":"LRR 11"}

Chain

Residue

Details

site_id	SWS_FT_FI32
Number of Residues	21
Details	Repeat: {"description":"LRR 12"}

Chain

Residue

Details

site_id	SWS_FT_FI33
Number of Residues	21
Details	Repeat: {"description":"LRR 13"}

Chain

Residue

Details

site_id	SWS_FT_FI34
Number of Residues	20
Details	Repeat: {"description":"LRR 14"}

Chain

Residue

Details

site_id	SWS_FT_FI35
Number of Residues	21
Details	Repeat: {"description":"LRR 15"}

Chain

Residue

Details

site_id	SWS_FT_FI36
Number of Residues	22
Details	Repeat: {"description":"LRR 16"}

Chain

Residue

Details

site_id	SWS_FT_FI37
Number of Residues	21
Details	Repeat: {"description":"LRR 17"}

Chain

Residue

Details

site_id	SWS_FT_FI38
Number of Residues	21
Details	Repeat: {"description":"LRR 18"}

Chain

Residue

Details

site_id	SWS_FT_FI39
Number of Residues	21
Details	Repeat: {"description":"LRR 19"}

Chain

Residue

Details

site_id	SWS_FT_FI40
Number of Residues	21
Details	Repeat: {"description":"LRR 20"}

Chain

Residue

Details

site_id	SWS_FT_FI41
Number of Residues	21
Details	Repeat: {"description":"LRR 21"}

Chain

Residue

Details

site_id	SWS_FT_FI42
Number of Residues	21
Details	Repeat: {"description":"LRR 22"}

Chain

Residue

Details

site_id	SWS_FT_FI43
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16043704","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22579623","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI44
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI45
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16043704","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22579623","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI46
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15961631","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22579623","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI47
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16043704","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI48
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22579623","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI49
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15961631","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16043704","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22579623","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI50
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)