Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9LRW

Cryo-EM structure of Fission yeast centromeric nucleosome Class 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000775	cellular_component	chromosome, centromeric region
A	0000776	cellular_component	kinetochore
A	0000779	cellular_component	condensed chromosome, centromeric region
A	0000785	cellular_component	chromatin
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0006325	biological_process	chromatin organization
A	0007080	biological_process	mitotic metaphase chromosome alignment
A	0019237	molecular_function	centromeric DNA binding
A	0030527	molecular_function	structural constituent of chromatin
A	0031492	molecular_function	nucleosomal DNA binding
A	0031507	biological_process	heterochromatin formation
A	0034080	biological_process	CENP-A containing chromatin assembly
A	0034506	cellular_component	chromosome, centromeric core domain
A	0043505	cellular_component	CENP-A containing nucleosome
A	0051382	biological_process	kinetochore assembly
A	0061638	cellular_component	CENP-A containing chromatin
B	0000786	cellular_component	nucleosome
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005694	cellular_component	chromosome
B	0006334	biological_process	nucleosome assembly
B	0006338	biological_process	chromatin remodeling
B	0030527	molecular_function	structural constituent of chromatin
B	0140463	molecular_function	chromatin-protein adaptor activity
C	0000786	cellular_component	nucleosome
C	0003677	molecular_function	DNA binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005694	cellular_component	chromosome
C	0005721	cellular_component	pericentric heterochromatin
C	0006302	biological_process	double-strand break repair
C	0007076	biological_process	mitotic chromosome condensation
C	0007095	biological_process	mitotic G2 DNA damage checkpoint signaling
C	0030527	molecular_function	structural constituent of chromatin
C	0031507	biological_process	heterochromatin formation
C	0031934	cellular_component	mating-type region heterochromatin
C	0033553	cellular_component	rDNA heterochromatin
C	0044773	biological_process	mitotic DNA damage checkpoint signaling
C	0045143	biological_process	homologous chromosome segregation
C	0099115	cellular_component	chromosome, subtelomeric region
C	0140463	molecular_function	chromatin-protein adaptor activity
D	0000724	biological_process	double-strand break repair via homologous recombination
D	0000786	cellular_component	nucleosome
D	0003677	molecular_function	DNA binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005694	cellular_component	chromosome
D	0006325	biological_process	chromatin organization
D	0006338	biological_process	chromatin remodeling
D	0030527	molecular_function	structural constituent of chromatin
D	0035861	cellular_component	site of double-strand break
D	0140463	molecular_function	chromatin-protein adaptor activity
E	0000775	cellular_component	chromosome, centromeric region
E	0000776	cellular_component	kinetochore
E	0000779	cellular_component	condensed chromosome, centromeric region
E	0000785	cellular_component	chromatin
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0006325	biological_process	chromatin organization
E	0007080	biological_process	mitotic metaphase chromosome alignment
E	0019237	molecular_function	centromeric DNA binding
E	0030527	molecular_function	structural constituent of chromatin
E	0031492	molecular_function	nucleosomal DNA binding
E	0031507	biological_process	heterochromatin formation
E	0034080	biological_process	CENP-A containing chromatin assembly
E	0034506	cellular_component	chromosome, centromeric core domain
E	0043505	cellular_component	CENP-A containing nucleosome
E	0051382	biological_process	kinetochore assembly
E	0061638	cellular_component	CENP-A containing chromatin
F	0000786	cellular_component	nucleosome
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005694	cellular_component	chromosome
F	0006334	biological_process	nucleosome assembly
F	0006338	biological_process	chromatin remodeling
F	0030527	molecular_function	structural constituent of chromatin
F	0140463	molecular_function	chromatin-protein adaptor activity
G	0000786	cellular_component	nucleosome
G	0003677	molecular_function	DNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005694	cellular_component	chromosome
G	0005721	cellular_component	pericentric heterochromatin
G	0006302	biological_process	double-strand break repair
G	0007076	biological_process	mitotic chromosome condensation
G	0007095	biological_process	mitotic G2 DNA damage checkpoint signaling
G	0030527	molecular_function	structural constituent of chromatin
G	0031507	biological_process	heterochromatin formation
G	0031934	cellular_component	mating-type region heterochromatin
G	0033553	cellular_component	rDNA heterochromatin
G	0044773	biological_process	mitotic DNA damage checkpoint signaling
G	0045143	biological_process	homologous chromosome segregation
G	0099115	cellular_component	chromosome, subtelomeric region
G	0140463	molecular_function	chromatin-protein adaptor activity
H	0000724	biological_process	double-strand break repair via homologous recombination
H	0000786	cellular_component	nucleosome
H	0003677	molecular_function	DNA binding
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005694	cellular_component	chromosome
H	0006325	biological_process	chromatin organization
H	0006338	biological_process	chromatin remodeling
H	0030527	molecular_function	structural constituent of chromatin
H	0035861	cellular_component	site of double-strand break
H	0140463	molecular_function	chromatin-protein adaptor activity

Functional Information from PROSITE/UniProt

site_id	PS00014
Number of Residues	4
Details	ER_TARGET Endoplasmic reticulum targeting sequence. SQEL

Chain	Residue	Details
C	SER129-LEU132

site_id	PS00046
Number of Residues	7
Details	HISTONE_H2A Histone H2A signature. AGLaFPV

Chain	Residue	Details
C	ALA23-VAL29

site_id	PS00047
Number of Residues	5
Details	HISTONE_H4 Histone H4 signature. GAKRH

Chain	Residue	Details
B	GLY15-HIS19

site_id	PS00357
Number of Residues	23
Details	HISTONE_H2B Histone H2B signature. REIQTavRlILpGELaKHAVTEG

Chain	Residue	Details
D	ARG92-GLY114

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18257517","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N6-glutaryllysine","evidences":[{"source":"UniProtKB","id":"P02309","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"N5-methylglutamine","evidences":[{"source":"UniProtKB","id":"P04911","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"16688222","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)