9LP9

The cryo-EM structure of retron Eco8 in a standby state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003964	molecular_function	RNA-directed DNA polymerase activity
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0046872	molecular_function	metal ion binding
A	0051607	biological_process	defense response to virus
B	0000166	molecular_function	nucleotide binding
B	0004518	molecular_function	nuclease activity
B	0005524	molecular_function	ATP binding
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
B	0051607	biological_process	defense response to virus
E	0000166	molecular_function	nucleotide binding
E	0004518	molecular_function	nuclease activity
E	0005524	molecular_function	ATP binding
E	0016787	molecular_function	hydrolase activity
E	0046872	molecular_function	metal ion binding
E	0051607	biological_process	defense response to virus
F	0003723	molecular_function	RNA binding
F	0003964	molecular_function	RNA-directed DNA polymerase activity
F	0016740	molecular_function	transferase activity
F	0016779	molecular_function	nucleotidyltransferase activity
F	0046872	molecular_function	metal ion binding
F	0051607	biological_process	defense response to virus
I	0000166	molecular_function	nucleotide binding
I	0004518	molecular_function	nuclease activity
I	0005524	molecular_function	ATP binding
I	0016787	molecular_function	hydrolase activity
I	0046872	molecular_function	metal ion binding
I	0051607	biological_process	defense response to virus
J	0003723	molecular_function	RNA binding
J	0003964	molecular_function	RNA-directed DNA polymerase activity
J	0016740	molecular_function	transferase activity
J	0016779	molecular_function	nucleotidyltransferase activity
J	0046872	molecular_function	metal ion binding
J	0051607	biological_process	defense response to virus
M	0000166	molecular_function	nucleotide binding
M	0004518	molecular_function	nuclease activity
M	0005524	molecular_function	ATP binding
M	0016787	molecular_function	hydrolase activity
M	0046872	molecular_function	metal ion binding
M	0051607	biological_process	defense response to virus
N	0003723	molecular_function	RNA binding
N	0003964	molecular_function	RNA-directed DNA polymerase activity
N	0016740	molecular_function	transferase activity
N	0016779	molecular_function	nucleotidyltransferase activity
N	0046872	molecular_function	metal ion binding
N	0051607	biological_process	defense response to virus

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	688
Details	Region: {"description":"ATPase domain N-terminus","evidences":[{"source":"UniProtKB","id":"E8PLM2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	516
Details	Region: {"description":"ATPase domain C-terminus","evidences":[{"source":"UniProtKB","id":"E8PLM2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1252
Details	Region: {"description":"Toprim domain","evidences":[{"source":"UniProtKB","id":"E8PLM2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	40
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"E8PLM2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	908
Details	Domain: {"description":"Reverse transcriptase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00405","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00405","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---