9LP9
The cryo-EM structure of retron Eco8 in a standby state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| B | 0005524 | molecular_function | ATP binding |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0016887 | molecular_function | ATP hydrolysis activity |
| F | 0003723 | molecular_function | RNA binding |
| F | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| F | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| I | 0005524 | molecular_function | ATP binding |
| I | 0016887 | molecular_function | ATP hydrolysis activity |
| J | 0003723 | molecular_function | RNA binding |
| J | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| J | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| M | 0005524 | molecular_function | ATP binding |
| M | 0016887 | molecular_function | ATP hydrolysis activity |
| N | 0003723 | molecular_function | RNA binding |
| N | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| N | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 688 |
| Details | Region: {"description":"ATPase domain N-terminus","evidences":[{"source":"UniProtKB","id":"E8PLM2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 516 |
| Details | Region: {"description":"ATPase domain C-terminus","evidences":[{"source":"UniProtKB","id":"E8PLM2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1252 |
| Details | Region: {"description":"Toprim domain","evidences":[{"source":"UniProtKB","id":"E8PLM2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 40 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"E8PLM2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 908 |
| Details | Domain: {"description":"Reverse transcriptase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00405","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00405","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
