9LOU

LGP2:dsRNA complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002753	biological_process	cytoplasmic pattern recognition receptor signaling pathway
A	0003724	molecular_function	RNA helicase activity
A	0003725	molecular_function	double-stranded RNA binding
A	0003727	molecular_function	single-stranded RNA binding
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0005829	cellular_component	cytosol
A	0008270	molecular_function	zinc ion binding
A	0009615	biological_process	response to virus
A	0016887	molecular_function	ATP hydrolysis activity
A	0032480	biological_process	negative regulation of type I interferon production
A	0032481	biological_process	positive regulation of type I interferon production
A	0039534	biological_process	negative regulation of MDA-5 signaling pathway
A	0039536	biological_process	negative regulation of RIG-I signaling pathway
A	0045088	biological_process	regulation of innate immune response
A	0045824	biological_process	negative regulation of innate immune response
A	0140374	biological_process	antiviral innate immune response
A	1900245	biological_process	positive regulation of MDA-5 signaling pathway
A	1900246	biological_process	positive regulation of RIG-I signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	177
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	130
Details	Domain: {"description":"RLR CTR","evidences":[{"source":"PROSITE-ProRule","id":"PRU01125","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	83
Details	Region: {"description":"RNA-binding"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	3
Details	Motif: {"description":"DECH box"}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01125","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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