9LKX
local refinement of FEM1B bound with PLD6
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| J | 0000151 | cellular_component | ubiquitin ligase complex |
| J | 0005123 | molecular_function | death receptor binding |
| J | 0005515 | molecular_function | protein binding |
| J | 0005634 | cellular_component | nucleus |
| J | 0005654 | cellular_component | nucleoplasm |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0005739 | cellular_component | mitochondrion |
| J | 0005829 | cellular_component | cytosol |
| J | 0006915 | biological_process | apoptotic process |
| J | 0016567 | biological_process | protein ubiquitination |
| J | 0031462 | cellular_component | Cul2-RING ubiquitin ligase complex |
| J | 0043161 | biological_process | proteasome-mediated ubiquitin-dependent protein catabolic process |
| J | 0046872 | molecular_function | metal ion binding |
| J | 0140627 | biological_process | ubiquitin-dependent protein catabolic process via the C-end degron rule pathway |
| J | 1902041 | biological_process | regulation of extrinsic apoptotic signaling pathway via death domain receptors |
| J | 1990756 | molecular_function | ubiquitin-like ligase-substrate adaptor activity |
| J | 2000001 | biological_process | regulation of DNA damage checkpoint |
| K | 0003824 | molecular_function | catalytic activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 29 |
| Details | Repeat: {"description":"ANK 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 29 |
| Details | Repeat: {"description":"ANK 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 29 |
| Details | Repeat: {"description":"ANK 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 29 |
| Details | Repeat: {"description":"ANK 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 29 |
| Details | Repeat: {"description":"ANK 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 30 |
| Details | Repeat: {"description":"ANK 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 33 |
| Details | Repeat: {"description":"TPR"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 44 |
| Details | Repeat: {"description":"ANK 7"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 37 |
| Details | Repeat: {"description":"ANK 8"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9Z2G0","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by a caspase-3-like protease","evidences":[{"source":"PubMed","id":"10542291","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
