9LFL
Cryo-EM structure of linker-extended biparatopic antibody BA1-GP4 in complex with TNFR2
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| B | TYR200-HIS206 | |
| E | TYR191-HIS197 | |
| D | TYR199-HIS205 | |
| C | TYR192-HIS198 |
| site_id | PS00652 |
| Number of Residues | 36 |
| Details | TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Crlrey.Ydqtaqm....C..Csk.Cspgqhakvf..Ctkts..DTVC |
| Chain | Residue | Details |
| A | CYS18-CYS53 | |
| A | CYS56-CYS96 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 37 |
| Details | Repeat: {"description":"TNFR-Cys 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 41 |
| Details | Repeat: {"description":"TNFR-Cys 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 43 |
| Details | Repeat: {"description":"TNFR-Cys 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"O-linked (GalNAc...) threonine","evidences":[{"source":"PubMed","id":"25456591","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
